UniProtKB - G1KKH5 (G1KKH5_ANOCA)
Protein
Submitted name:
Uncharacterized protein
Gene
C9orf72
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- guanyl-nucleotide exchange factor activity Source: InterPro
- Rab GTPase binding Source: Ensembl
GO - Biological processi
- autophagy Source: GO_Central
- axon extension Source: Ensembl
- endocytosis Source: GO_Central
- late endosome to lysosome transport Source: Ensembl
- negative regulation of GTP binding Source: Ensembl
- negative regulation of protein phosphorylation Source: Ensembl
- regulation of actin filament organization Source: Ensembl
- regulation of autophagy Source: Ensembl
- regulation of TORC1 signaling Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:C9orf72Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Endosome
- endosome Source: GO_Central
Extracellular region or secreted
- extracellular space Source: Ensembl
Nucleus
- nucleus Source: Ensembl
Other locations
- autophagosome Source: GO_Central
- neuron projection Source: Ensembl
- perikaryon Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000010697, Expressed in brain and 14 other tissues |
Interactioni
GO - Molecular functioni
- guanyl-nucleotide exchange factor activity Source: InterPro
- Rab GTPase binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000010554 |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502QSST, Eukaryota |
GeneTreei | ENSGT00390000005644 |
HOGENOMi | CLU_047573_0_0_1 |
InParanoidi | G1KKH5 |
OMAi | KTHSVPE |
OrthoDBi | 1434762at2759 |
TreeFami | TF313315 |
Family and domain databases
InterProi | View protein in InterPro IPR027819, C9orf72 |
PANTHERi | PTHR31855, PTHR31855, 1 hit |
Pfami | View protein in Pfam PF15019, C9orf72-like, 1 hit |
PROSITEi | View protein in PROSITE PS51835, DENN_C9ORF72, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KKH5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSALCPPPSP AVAKTEIALS GESPLLAATF AYWDNILGPR VRHIWAPKAE
60 70 80 90 100
QQLLSDGEII FLANHTLNGE ILRNAESGAI DVKFFVLAEK GVIIVSLIFD
110 120 130 140 150
GNWNGDRSTY GLSIILPQSE LSFYLPLHRV CVDRLTHIIR KGRIWMHKER
160 170 180 190 200
QEHFQKAVME GTERMEDQGQ SIIPMLTGEV IPVMELLSSM KSHSVPEEID
210 220 230 240 250
ICDTVLSDDD IGDSCHEGFL LKAISSHLQT CGCSVIVGSS AEKVNKIVRT
260 270 280 290 300
LCLFLTSAER KCSRLCRNET SFKYESGLFV QGLLKDVTGS FVLPFRQVMY
310 320 330 340 350
APYPTTHIDV DVNTVKQMPP CHEHIYNQRR YMRSELTAFW RATSDEDVVQ
360 370 380 390 400
DTVIHTDESF TPDLNVFQDV LHQDTLVKAF LDQVFHLKPG LSLRSVFLAQ
410 420 430 440 450
FLLVLHRKAL TLIKYIEDDT QKGKKPFKSL RSLKIDLDLT AEGDLNIVMA
460 470 480
LAEKIKPGLH SFLFGRPFYT SVQEHDVLMA F
Sequence databases
RefSeqi | XP_003216675.1, XM_003216627.2 XP_008101710.1, XM_008103503.2 |
Genome annotation databases
Ensembli | ENSACAT00000010772; ENSACAP00000010554; ENSACAG00000010697 |
GeneIDi | 100564635 |
KEGGi | acs:100564635 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003216675.1, XM_003216627.2 XP_008101710.1, XM_008103503.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000010554 |
Genome annotation databases
Ensembli | ENSACAT00000010772; ENSACAP00000010554; ENSACAG00000010697 |
GeneIDi | 100564635 |
KEGGi | acs:100564635 |
Organism-specific databases
CTDi | 203228 |
Phylogenomic databases
eggNOGi | ENOG502QSST, Eukaryota |
GeneTreei | ENSGT00390000005644 |
HOGENOMi | CLU_047573_0_0_1 |
InParanoidi | G1KKH5 |
OMAi | KTHSVPE |
OrthoDBi | 1434762at2759 |
TreeFami | TF313315 |
Gene expression databases
Bgeei | ENSACAG00000010697, Expressed in brain and 14 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR027819, C9orf72 |
PANTHERi | PTHR31855, PTHR31855, 1 hit |
Pfami | View protein in Pfam PF15019, C9orf72-like, 1 hit |
PROSITEi | View protein in PROSITE PS51835, DENN_C9ORF72, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KKH5_ANOCA | |
Accessioni | G1KKH5Primary (citable) accession number: G1KKH5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | February 10, 2021 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |