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Entry version 62 (12 Aug 2020)
Sequence version 1 (19 Oct 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000010529, Expressed in hemipenis and 14 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini12 – 83KRABInterPro annotationAdd BLAST72
Domaini150 – 177C2H2-typeInterPro annotationAdd BLAST28
Domaini178 – 205C2H2-typeInterPro annotationAdd BLAST28
Domaini206 – 233C2H2-typeInterPro annotationAdd BLAST28
Domaini234 – 261C2H2-typeInterPro annotationAdd BLAST28
Domaini262 – 289C2H2-typeInterPro annotationAdd BLAST28
Domaini290 – 317C2H2-typeInterPro annotationAdd BLAST28
Domaini318 – 345C2H2-typeInterPro annotationAdd BLAST28
Domaini346 – 373C2H2-typeInterPro annotationAdd BLAST28
Domaini374 – 401C2H2-typeInterPro annotationAdd BLAST28
Domaini402 – 429C2H2-typeInterPro annotationAdd BLAST28
Domaini430 – 457C2H2-typeInterPro annotationAdd BLAST28
Domaini458 – 485C2H2-typeInterPro annotationAdd BLAST28
Domaini486 – 513C2H2-typeInterPro annotationAdd BLAST28
Domaini514 – 541C2H2-typeInterPro annotationAdd BLAST28
Domaini542 – 569C2H2-typeInterPro annotationAdd BLAST28
Domaini570 – 597C2H2-typeInterPro annotationAdd BLAST28
Domaini598 – 625C2H2-typeInterPro annotationAdd BLAST28
Domaini626 – 653C2H2-typeInterPro annotationAdd BLAST28
Domaini654 – 681C2H2-typeInterPro annotationAdd BLAST28
Domaini682 – 709C2H2-typeInterPro annotationAdd BLAST28
Domaini710 – 737C2H2-typeInterPro annotationAdd BLAST28
Domaini738 – 766C2H2-typeInterPro annotationAdd BLAST29
Domaini767 – 794C2H2-typeInterPro annotationAdd BLAST28
Domaini795 – 822C2H2-typeInterPro annotationAdd BLAST28
Domaini823 – 850C2H2-typeInterPro annotationAdd BLAST28
Domaini852 – 879C2H2-typeInterPro annotationAdd BLAST28
Domaini880 – 907C2H2-typeInterPro annotationAdd BLAST28
Domaini908 – 935C2H2-typeInterPro annotationAdd BLAST28
Domaini936 – 963C2H2-typeInterPro annotationAdd BLAST28
Domaini964 – 992C2H2-typeInterPro annotationAdd BLAST29
Domaini993 – 1020C2H2-typeInterPro annotationAdd BLAST28
Domaini1021 – 1048C2H2-typeInterPro annotationAdd BLAST28
Domaini1049 – 1076C2H2-typeInterPro annotationAdd BLAST28
Domaini1077 – 1104C2H2-typeInterPro annotationAdd BLAST28
Domaini1105 – 1132C2H2-typeInterPro annotationAdd BLAST28
Domaini1133 – 1156C2H2-typeInterPro annotationAdd BLAST24

Keywords - Domaini

RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT01000000214429

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_17_1_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
G1KK75

Identification of Orthologs from Complete Genome Data

More...
OMAi
GKCFARH

TreeFam database of animal gene trees

More...
TreeFami
TF343410

Family and domain databases

Conserved Domains Database

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CDDi
cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 31 hits

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 36 hits

Superfamily database of structural and functional annotation

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SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 18 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 36 hits
PS50157, ZINC_FINGER_C2H2_2, 36 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KK75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LKGETGSFQR PLTFKDVAVY FTEGQGSLLD PDQKALYKEV MMENYENVAS
60 70 80 90 100
LGLLLSKPTL IFHLEQGEEP WLPDTRPFRN SYSVVYDHIK QTDSHIKQII
110 120 130 140 150
SGNMKKVAIS NIHQYNLLFK GQFSIGLALC HRGGYRKKHA CRKCGKSFAQ
160 170 180 190 200
KCLECAKHFV HHSELMKHQR VHTGERPFWC LECGKCFSRQ SVLVNHHRIH
210 220 230 240 250
TGEKPYKCLE CVKCFTQRSQ LVRHLRVHTG EKPYECLECG KCFARHSVLI
260 270 280 290 300
NHQRVHTGEK PYKCLECAKC FARQSVLVNH QRVHTGEKPY KCQECGKRFA
310 320 330 340 350
HQSNLVNHQR VHTGEKPYKC LKCGKCFAQQ SDVVNHQRVH TGEKPHKCLE
360 370 380 390 400
CGKCFSQRSA LVSHQRIHTG EKPYKCVECE KCFAQLSNLV KHQRVHTGEK
410 420 430 440 450
PYECLECGKA FQQKSELVMH RIIHPGEKPF KCLECAKDFN HHSELVKHQR
460 470 480 490 500
IHTGERPFQC LECGKCFSRQ SVLMNHHRIH TGEKPYKCLE CAKCFTERSQ
510 520 530 540 550
LVRHLKVHTG EKPYECLECG KCFARHEVFV NHQRVHTGEK PYKCMECSRC
560 570 580 590 600
FGRQSVLVSH QRVHTGEKPY KCQECGKCFA HQSNLVNHHR VHTGEKPYEC
610 620 630 640 650
LKCGKCFAQQ SDLVKHRRIH TVEKPYKCLV CGKCFAVHSD VVNHQQIHTG
660 670 680 690 700
ERPHKCSECG KCFAQHSALV SHQRVHTAEK PHKCQECGKC FAQRSTLVSH
710 720 730 740 750
QRIHTGEKPY KCAVCGKTFA ELSNLGKHQK VHTGEKRYAC LECGKRFARH
760 770 780 790 800
AHLQVHHRVH HKGQRSYKCL ECGESFKRHS LFVRHWRVHT GENPYECQEC
810 820 830 840 850
GRSYLRPSAL VSHWMVHTGE QPYECLECGK GFPRPSALVK HSRVHSTKKP
860 870 880 890 900
KNVCLECGKH FAREVNLLAH QVTHVRDRRR KCLQCGEDFA NYLAYLRHQK
910 920 930 940 950
IHKKKRSYKC LECGECFEYR YHMVVHQKVH METNPFKCSE CGECFDEHSA
960 970 980 990 1000
LVSHWMVHTG EQPYECRECG KGFPRPSELV LHCRVHTTGE KPYKCLECGK
1010 1020 1030 1040 1050
GFNQNSSLTA HVRIHTGEKP YKCLTCGKSF CRSSHLTSHR RTHTGEKPHK
1060 1070 1080 1090 1100
CAECGKSFSQ RSHLTSHQRT HTGEKPYKCT ECGKGFSQCS SLTSHQRTHL
1110 1120 1130 1140 1150
GEKPYNCGDC GKNFNTKSSL TVHQRTHTGE KPYSCTVCGK TFSDGGTLIK

HQRTHT
Length:1,156
Mass (Da):133,375
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i74C0B9950739315A
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000010535; ENSACAP00000010323; ENSACAG00000010529

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSACAT00000010535; ENSACAP00000010323; ENSACAG00000010529

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT01000000214429
HOGENOMiCLU_002678_17_1_1
InParanoidiG1KK75
OMAiGKCFARH
TreeFamiTF343410

Gene expression databases

BgeeiENSACAG00000010529, Expressed in hemipenis and 14 other tissues

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 31 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 36 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 18 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 36 hits
PS50157, ZINC_FINGER_C2H2_2, 36 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KK75_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KK75
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: August 12, 2020
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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