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Entry version 44 (12 Aug 2020)
Sequence version 1 (19 Oct 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene

xirp1

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:xirp1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000009771, Expressed in skeletal muscle tissue and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000009563

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati115 – 130XinPROSITE-ProRule annotationAdd BLAST16
Repeati181 – 196XinPROSITE-ProRule annotationAdd BLAST16
Repeati220 – 235XinPROSITE-ProRule annotationAdd BLAST16
Repeati260 – 275XinPROSITE-ProRule annotationAdd BLAST16
Repeati298 – 313XinPROSITE-ProRule annotationAdd BLAST16
Repeati336 – 351XinPROSITE-ProRule annotationAdd BLAST16
Repeati373 – 388XinPROSITE-ProRule annotationAdd BLAST16
Repeati407 – 422XinPROSITE-ProRule annotationAdd BLAST16
Repeati444 – 459XinPROSITE-ProRule annotationAdd BLAST16
Repeati480 – 495XinPROSITE-ProRule annotationAdd BLAST16
Repeati515 – 530XinPROSITE-ProRule annotationAdd BLAST16
Repeati554 – 569XinPROSITE-ProRule annotationAdd BLAST16
Repeati592 – 607XinPROSITE-ProRule annotationAdd BLAST16
Repeati630 – 645XinPROSITE-ProRule annotationAdd BLAST16
Repeati664 – 679XinPROSITE-ProRule annotationAdd BLAST16
Repeati703 – 718XinPROSITE-ProRule annotationAdd BLAST16
Repeati742 – 757XinPROSITE-ProRule annotationAdd BLAST16
Repeati780 – 795XinPROSITE-ProRule annotationAdd BLAST16
Repeati816 – 831XinPROSITE-ProRule annotationAdd BLAST16
Repeati853 – 868XinPROSITE-ProRule annotationAdd BLAST16
Repeati891 – 906XinPROSITE-ProRule annotationAdd BLAST16
Repeati928 – 943XinPROSITE-ProRule annotationAdd BLAST16
Repeati962 – 977XinPROSITE-ProRule annotationAdd BLAST16
Repeati993 – 1008XinPROSITE-ProRule annotationAdd BLAST16
Repeati1031 – 1046XinPROSITE-ProRule annotationAdd BLAST16
Repeati1066 – 1081XinPROSITE-ProRule annotationAdd BLAST16

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 56DisorderedSequence analysisAdd BLAST56
Regioni1531 – 1554DisorderedSequence analysisAdd BLAST24
Regioni1699 – 1785DisorderedSequence analysisAdd BLAST87
Regioni1803 – 1822DisorderedSequence analysisAdd BLAST20
Regioni1888 – 1916DisorderedSequence analysisAdd BLAST29

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1157 – 1177Sequence analysisAdd BLAST21
Coiled coili1465 – 1485Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1531 – 1546PolarSequence analysisAdd BLAST16
Compositional biasi1764 – 1785Pro-richSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Xin repeats bind F-actin.PROSITE-ProRule annotation

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Xin family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QTAC, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063779

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_245717_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1KJB0

Identification of Orthologs from Complete Genome Data

More...
OMAi
KNYKWMF

TreeFam database of animal gene trees

More...
TreeFami
TF330745

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012510, Actin-binding_Xin_repeat
IPR030072, XIRP1/XIRP2

The PANTHER Classification System

More...
PANTHERi
PTHR22591, PTHR22591, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08043, Xin, 14 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51389, XIN, 26 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KJB0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEAQNDRNP TSNIRKIDEN LPPPPPPPSQ DSAPGAASIA RSQNSSPLPP
60 70 80 90 100
PPPKETFSKF YQQRQVNELK RLYRHMHPEL RKNLEEAVTE DLAEMLSTDD
110 120 130 140 150
PNAQASMSLD AVLPGEVQSM RWIFENWTLD SIGEHQAAKK LAEEEAIPSG
160 170 180 190 200
DVKNRSMRFE SPLPNGNGPS AKVSETEQTK GDVRTARWLF ETQPLDALNK
210 220 230 240 250
MYLDETDLQE AVLKEPVEKG DVKGAAQLFE THSLDALGRC CSVEEQSILQ
260 270 280 290 300
LKSEIQEHKG DVKKTIKLFQ TEPLCAIRDQ TGHIHEIKSV CREEIQSNAV
310 320 330 340 350
KTARWLFETQ PLDTINKDTS KVQVIRGISL EEAAKGNVSG AKWLFETQPL
360 370 380 390 400
DAIREITVEE SDFKASPDLI QGADVSKQCL LFETQPLDAL KGESSNSIPT
410 420 430 440 450
REEVVKGDVK SSLWLFETQP METLRDSYEV GHLMKVELTD EEKGAVKQTK
460 470 480 490 500
HVFETCPLGS IAKSPAGDIS TTNIQEVEKG DVKAFKSLFE TLPLDSIRQV
510 520 530 540 550
SSEEMVEKSE EIPPGNVKAN QILFETTPLY AIKDCFGNFH KVTSVSREEE
560 570 580 590 600
VTGGDVKNYK WMFETKPLDQ FDDSTQKVAL VKGITKQEVV AGDVKTAKWL
610 620 630 640 650
FETQPIDVIH SQMNPADQDI SEKGEATQKG DVKTCRWLFE THPMDTLYEK
660 670 680 690 700
EGEKQDGEEC VPQGDVKSCT WMFETQPLDS LKGQEEQYLQ VSKVYNQDEL
710 720 730 740 750
QGVDVKTVRH LFETEPLVSD TTNSGDTKKI IRYSSRVEMQ SGEVSRVKEF
760 770 780 790 800
FEAKPLDSMH KPSIDKKASE TPAHGDIERG AVHKFTWLFE NCPMDTLKSS
810 820 830 840 850
MEGIQEVAPQ KDIQGGDVGG KRFVFETYSL DQIHDKENEM QIKKIQEETM
860 870 880 890 900
NKADIKSCTM LFETRPLYAI QDKEGEYHEV TSVKKEEIMK GDVKGARWQF
910 920 930 940 950
ETKPLDQIKK DEEVFVIRAV TQEDFKKGDV QAARWRFETE PLDSIAEEKR
960 970 980 990 1000
SVLKTIDDVQ KGDVQSNKQL FESDQASQRK YVRMVSVSDV QHGDVRTSTW
1010 1020 1030 1040 1050
LFENQPIDSL KGESESTSCL STVQREDIHK GDVKRCTWMF ETQPMDSLKD
1060 1070 1080 1090 1100
PEAPANVETL RVAPQADVKS TTWLFESTPL DKLSTTRHCA EKDATQRAIT
1110 1120 1130 1140 1150
STLEVLFSRQ VVKHGGILIE ANDTESITMA KYHLGPHGSP EVQKEEVMGG
1160 1170 1180 1190 1200
NLQNILMQLL QRSNIEAKGE LVQEEENGEI RVRPVQLLDT GKAEKSREDL
1210 1220 1230 1240 1250
KDDVAKALQD LLSQGTSIKK GLLMQETETG SAKITIFSLL HRIDQDHSLV
1260 1270 1280 1290 1300
KGDVKSTIGN LLASSQEQKA TATIRREDNE KGNVQLYTSC IEKGDLDYLK
1310 1320 1330 1340 1350
NLQRESEIES LASSQVQEEP METVQQAKVT AQLPEGKLVP QMAGVVLGDI
1360 1370 1380 1390 1400
SGTKQVFLCK SKEGTLEREA EIGSTEHCLV QSLKPVVVEG NQVPGQVKFP
1410 1420 1430 1440 1450
IESVQKAQDD SNRVVREEKI ILGEREEGSA TTKVTEQMKV TSGTTHSSPL
1460 1470 1480 1490 1500
GTVDQPQTPA LGSDLQAAMQ SLRLATAEAQ SLRHQFQSKL QKTTEEIQQP
1510 1520 1530 1540 1550
TQTATVQVAG CHKGCVATSH QQAGNATFLS VQETPKSQQS MPQKSMAPHP
1560 1570 1580 1590 1600
KVSASEQDGV LPFAAPKDGP SAELSIKDGL YTAKPVKPYV NPFAESDYKE
1610 1620 1630 1640 1650
HSVPEEREQE PIIGGDVQTA IRALQSAATG QRPVDKEDVV RGNLKAALES
1660 1670 1680 1690 1700
LEKFNVNVSK GDFKAAMIYR QAGQSYSICK KKNETQILSN QAAAVEASGS
1710 1720 1730 1740 1750
QAINDCPPPS PASVMGTECQ PSKQKEAKAL RCSSLAQPHV PKAPPPAPTK
1760 1770 1780 1790 1800
PSDQKALEKP QLPPKPEVIA PPRRKPVPPP KPEFLLKEAL PHPASCKKGT
1810 1820 1830 1840 1850
LGIETTQLSS PKPLTEVEQS KSKTLPIPDC AKAAFGTEIW EPSPCQQHST
1860 1870 1880 1890 1900
VAPVAPSSVS TVVEDFRSEK KPRRDMVKTP LQVAEEKYKA KKEEQSKVEL
1910
GGQKLSVEAA KMRSEG
Length:1,916
Mass (Da):212,626
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i23A70DC8008B2867
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000009760; ENSACAP00000009563; ENSACAG00000009771

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000009563

Genome annotation databases

EnsembliENSACAT00000009760; ENSACAP00000009563; ENSACAG00000009771

Phylogenomic databases

eggNOGiENOG502QTAC, Eukaryota
GeneTreeiENSGT00530000063779
HOGENOMiCLU_245717_0_0_1
InParanoidiG1KJB0
OMAiKNYKWMF
TreeFamiTF330745

Gene expression databases

BgeeiENSACAG00000009771, Expressed in skeletal muscle tissue and 5 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR012510, Actin-binding_Xin_repeat
IPR030072, XIRP1/XIRP2
PANTHERiPTHR22591, PTHR22591, 1 hit
PfamiView protein in Pfam
PF08043, Xin, 14 hits
PROSITEiView protein in PROSITE
PS51389, XIN, 26 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KJB0_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KJB0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: August 12, 2020
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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