UniProtKB - G1KIK7 (G1KIK7_ANOCA)
Protein
Submitted name:
Uncharacterized protein
Gene
SBF2
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- phosphatase binding Source: Ensembl
- phosphatase regulator activity Source: Ensembl
- phosphatidylinositol binding Source: Ensembl
- Rab guanyl-nucleotide exchange factor activity Source: GO_Central
GO - Biological processi
- regulation of GTPase activity Source: InterPro
Keywordsi
Molecular function | Guanine-nucleotide releasing factorARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:SBF2Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Other locations
- vacuolar membrane Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000009005, Expressed in embryonic post-anal tail and 14 other tissues |
Interactioni
GO - Molecular functioni
- phosphatase binding Source: Ensembl
- Rab guanyl-nucleotide exchange factor activity Source: GO_Central
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000008996 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 7 – 424 | UDENNInterPro annotationAdd BLAST | 418 | |
Domaini | 1106 – 1587 | Myotubularin phosphataseInterPro annotationAdd BLAST | 482 | |
Domaini | 1746 – 1850 | PHInterPro annotationAdd BLAST | 105 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1074 – 1100 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 1711 – 1730 | DisorderedSequence analysisAdd BLAST | 20 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 1642 – 1662 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1715 – 1730 | PolarSequence analysisAdd BLAST | 16 |
Sequence similaritiesi
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG1090, Eukaryota KOG4471, Eukaryota |
GeneTreei | ENSGT00940000155385 |
HOGENOMi | CLU_002298_1_1_1 |
InParanoidi | G1KIK7 |
TreeFami | TF318583 |
Family and domain databases
CDDi | cd13339, PH-GRAM_MTMR13, 1 hit |
Gene3Di | 2.30.29.30, 1 hit 3.40.50.11500, 1 hit |
InterProi | View protein in InterPro IPR001194, cDENN_dom IPR005112, dDENN_dom IPR043153, DENN_C IPR004182, GRAM IPR030567, MTMR13 IPR037823, MTMR13_PH-GRAM IPR010569, Myotubularin-like_Pase_dom IPR030564, Myotubularin_fam IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR029021, Prot-tyrosine_phosphatase-like IPR022096, SBF1/SBF2 IPR037516, Tripartite_DENN IPR005113, uDENN_dom |
PANTHERi | PTHR10807, PTHR10807, 1 hit PTHR10807:SF4, PTHR10807:SF4, 1 hit |
Pfami | View protein in Pfam PF02141, DENN, 1 hit PF02893, GRAM, 1 hit PF06602, Myotub-related, 1 hit PF00169, PH, 1 hit PF12335, SBF2, 1 hit PF03456, uDENN, 1 hit |
SMARTi | View protein in SMART SM00801, dDENN, 1 hit SM00799, DENN, 1 hit SM00568, GRAM, 1 hit SM00233, PH, 1 hit SM00800, uDENN, 1 hit |
SUPFAMi | SSF52799, SSF52799, 1 hit |
PROSITEi | View protein in PROSITE PS50211, DENN, 1 hit PS50003, PH_DOMAIN, 1 hit PS51339, PPASE_MYOTUBULARIN, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KIK7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MARLADYFIV VGYDHEKTGS GEGLGKIIQR FPLKDLDDTP FPQGIELFCQ
60 70 80 90 100
PGGWHLSKER KQPTFFVVVL TDINSERHYC SCLTFYEAEI NLQGTRETEG
110 120 130 140 150
EEESGLIQPA EVFAPKSLVL VSRLDYPEIF RACLGLVYTV YVDNLNVSLE
160 170 180 190 200
NLIANLCSCF VPAAGGSQKL FSLGAGDRQM IQTPLHDSLP VTGTSVALLF
210 220 230 240 250
QQLGIQNVLS LFCAVLTENK VLFHSASFQR LSDACRALES LMFPLKYSYP
260 270 280 290 300
YIPILPAQLL EVLSSPTPFI IGVHSIFCNE IHELLDVIIA DLDGGTIKIP
310 320 330 340 350
ECIHLSPLPE PLLHQTQTAL SLVLHPDLET ADYAFPPPRT ALSQSKMLDK
360 370 380 390 400
EVRGVFLRLF AQLFQGYRSC LQLIRIHAEP VINFHKAAFL GQRGLIENDF
410 420 430 440 450
LTKVLNGMAF AGFVSERGPP YRSCDLFDEL VAFEVERIKS EESNSSKMLK
460 470 480 490 500
HVRELAEQLF KNENPNPHMA FQKVPRPTEG SHLRIHVLPF PKINENQVQD
510 520 530 540 550
LIQDGLVKNQ SVQPASRIEK KCVVPAGPPV VSIVEKSSSV FNSAQRLEVV
560 570 580 590 600
RNCISFIFEN KILETEKTLP AALRALKGKV ARQCLTEELS LHVQQNRAIL
610 620 630 640 650
DHQQFDYIVR MMNCTLQDCS TSEEYNIAAA LLPLTTAFYR KLAPGVSQFA
660 670 680 690 700
YTCVQDHPIW ANQQFWETTF YSDVENQIRS LYLSSKEDNH PQYLKQKENN
710 720 730 740 750
SEGNTQEKTA MDLAAEQLRL WPTLSKEIQQ QLVQSEESMV FSQAIHFANL
760 770 780 790 800
MVYLLVPLDT SKNKLLRTSA TGDWESGSNS IVTNSIAGSV AESYDTESGF
810 820 830 840 850
EDSENNDIAN AVVRFITRFI DKVCTESGVT QDHIRSLHCM IPGIVAMHIE
860 870 880 890 900
TLEAVHRESR RLPPIQKPKI LRPALLPGEE FVCEGLRVLL DPDGREEATG
910 920 930 940 950
GLLGGPHILP AEGALFLTTY RVIFKGTPHD QLVGEQTVIR SFPVSSITKE
960 970 980 990 1000
KKITIQNQLQ QNMQEGLQIT SAAFQLIKVA FDEEVGPEVV EIFKKQLMKF
1010 1020 1030 1040 1050
RYPQSIFSTF AFAAGQTAPQ IILPKQKEKN TSFRTLSKTI VKGAKRAGKM
1060 1070 1080 1090 1100
TIGRQYLLKK KTTGTIVEER ANRPGWNEDD DISVSDDSEM HTSGTLKASE
1110 1120 1130 1140 1150
KSTMEQLVER ACFRDYQRLG LGTINNSSTR SKTEYFRITA LNRMYSLCRS
1160 1170 1180 1190 1200
YPGLLVVPQC VQDSNLQRVA RCYRHNRLPV VCWKNSKSSA LLLRAGGFHG
1210 1220 1230 1240 1250
KGVVGLFKSQ NTQTSAPTSL ESSSSIEQEK YLQALLNAIS VHCKMNGNNT
1260 1270 1280 1290 1300
LTIRPTIALS PGVWASLRSS SRFISTQMPF LDVGARLAGK DGSPSYSSSN
1310 1320 1330 1340 1350
AYFQNRLTKR QASLYVFGEK SQLRGFKLDF ALNCEFVPVE FSDLRQVKTS
1360 1370 1380 1390 1400
FKKLMSACIP SSIPSDPEIT FLKALGESEW FPQLHRIMQL SVVMSELLEN
1410 1420 1430 1440 1450
GSSVLVCLED GWDITAQVVS LVQLLSDPFY RTLEGFRMLV EKEWLSFGHK
1460 1470 1480 1490 1500
FSQRSNLTLN CQGSGFAPVF LQFLDCVHQV HNQYPTEFEF NQYYLKFLAF
1510 1520 1530 1540 1550
HYVSNRFKTF LLDSDYERLE HGTLFEDKGE KHGKKGICMW ECIDKIHKRS
1560 1570 1580 1590 1600
PVFFNYLYTP VETEASFSQV LKPNVNISSL KKWDYYTEET LATGPSYDWT
1610 1620 1630 1640 1650
MIISKCSTLD EPDQRDESSS HSKRKIVWPC YDDINKVQPD AITNLLNEIE
1660 1670 1680 1690 1700
RLENKLHQNP ERWQQLWERI KVNVKEDTKQ DNHRRHPSGS SAVMSANLHS
1710 1720 1730 1740 1750
YQKRSLLHVP DSGLGEEQNA NNSPSNGVER RVTTLYNQFT SKNDENRSFE
1760 1770 1780 1790 1800
GTLYKRGALL KGWKPRWFVL DVTKHQLRYY DSVDDACCRG HIDLAEVESV
1810 1820 1830 1840 1850
IPASPTIGAP KHTNEKAFFD LKTSKRVYNF CAQEAQSAQQ WMDRIQSCIS
DA
Genome annotation databases
Ensembli | ENSACAT00000009189; ENSACAP00000008996; ENSACAG00000009005 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000008996 |
Genome annotation databases
Ensembli | ENSACAT00000009189; ENSACAP00000008996; ENSACAG00000009005 |
Phylogenomic databases
eggNOGi | KOG1090, Eukaryota KOG4471, Eukaryota |
GeneTreei | ENSGT00940000155385 |
HOGENOMi | CLU_002298_1_1_1 |
InParanoidi | G1KIK7 |
TreeFami | TF318583 |
Gene expression databases
Bgeei | ENSACAG00000009005, Expressed in embryonic post-anal tail and 14 other tissues |
Family and domain databases
CDDi | cd13339, PH-GRAM_MTMR13, 1 hit |
Gene3Di | 2.30.29.30, 1 hit 3.40.50.11500, 1 hit |
InterProi | View protein in InterPro IPR001194, cDENN_dom IPR005112, dDENN_dom IPR043153, DENN_C IPR004182, GRAM IPR030567, MTMR13 IPR037823, MTMR13_PH-GRAM IPR010569, Myotubularin-like_Pase_dom IPR030564, Myotubularin_fam IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR029021, Prot-tyrosine_phosphatase-like IPR022096, SBF1/SBF2 IPR037516, Tripartite_DENN IPR005113, uDENN_dom |
PANTHERi | PTHR10807, PTHR10807, 1 hit PTHR10807:SF4, PTHR10807:SF4, 1 hit |
Pfami | View protein in Pfam PF02141, DENN, 1 hit PF02893, GRAM, 1 hit PF06602, Myotub-related, 1 hit PF00169, PH, 1 hit PF12335, SBF2, 1 hit PF03456, uDENN, 1 hit |
SMARTi | View protein in SMART SM00801, dDENN, 1 hit SM00799, DENN, 1 hit SM00568, GRAM, 1 hit SM00233, PH, 1 hit SM00800, uDENN, 1 hit |
SUPFAMi | SSF52799, SSF52799, 1 hit |
PROSITEi | View protein in PROSITE PS50211, DENN, 1 hit PS50003, PH_DOMAIN, 1 hit PS51339, PPASE_MYOTUBULARIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KIK7_ANOCA | |
Accessioni | G1KIK7Primary (citable) accession number: G1KIK7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | August 12, 2020 | |
This is version 67 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |