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Entry version 47 (29 Sep 2021)
Sequence version 2 (29 Sep 2021)
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Protein
Submitted name:

KIAA1217

Gene

KIAA1217

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • enzyme regulator activity Source: GO_Central

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
KIAA1217Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KIAA1217Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000008656, Expressed in hemipenis and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000008503

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQCT, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156098

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002507_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1KI23

TreeFam database of animal gene trees

More...
TreeFami
TF332255

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022782, AIP3-like_C
IPR026725, Skt

The PANTHER Classification System

More...
PANTHERi
PTHR22741:SF11, PTHR22741:SF11, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03915, AIP3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

G1KI23-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSSSSSPA SSSPARRSPL ARDFEEGGGG RSASLKRPSL PKSQLARCYS
60 70 80 90 100
VAIPHHASCI DVRVTRQSGW NTEFSYGTLD QGKSNLRGIS LDDADCLWPK
110 120 130 140 150
ELIASGNSQT SVSKAGRNIP RRHTVGGPRS SKEILGMQAS EMDKKREAFL
160 170 180 190 200
EHLKQKYPHH ATAIMGHQER LRDQTRSPKL SQSPQPNLGD QAEYLSEASA
210 220 230 240 250
DSLEIMSEGE PLSPFSRGSR TRASLPVVRT TNQTKERSLG ALYLQYGDET
260 270 280 290 300
KQLRMPNEIT STDTIRALFV SAFPQQLSMK ILESPSVAIY IKDESRNIYY
310 320 330 340 350
ELSDVRNIQD RSFLKVYNKD PAHAFNHMPR AVNGDIRMQR DIYSSASRPG
360 370 380 390 400
SATHHPPPPP HALPTSPPAT PVPHSMPPSP SRIPYSNVRP VSGPGNATIP
410 420 430 440 450
RDRLSNMPAS RSISPSPSAI LERRDVKPDE DMGNKTLTLY RNEGLYADPY
460 470 480 490 500
LYHDGRMSIA GSHTGHPLDI PDHVIAYHRS TMRSSSTYCN PPMQPEIMEQ
510 520 530 540 550
SLYRQKSRKY ADSHLPTLSS KTPPTSPHRV AEMRMIDIHT HHNTPMSPHA
560 570 580 590 600
IHLDRSSPGR QSLKKDPGTP VFMEGKPRNV MGLHGMTEVV PSVPDKKAFG
610 620 630 640 650
YGTVVIPKET ETRERMHAME KQIASLTGLV QSALLKGPNT SNSKDAPSEK
660 670 680 690 700
IVKTVSSKSN IERTGSAHVS GGKNSLAASE AAVATAANIS HSMPVGCTAM
710 720 730 740 750
QVSLFDMKRN VSDLRLQLHQ MRQLQLQNQE TLRAMVKKAE LEINDKVIER
760 770 780 790 800
AKKLEDPVQR QRHLVEQERQ KYLLEEERIV KSLCELESFV EDLKKETMTT
810 820 830 840 850
SRIVTLKDVE DGACLLRQVG EAVANLKGEF PTLQNKMRAI LRIEVEAVRF
860 870 880 890 900
LKEEPHKLDI LLKRVRSMTD TLTTLRRHVT DDLLKGVDPS QAAQYNAMEK
910 920 930 940 950
VTAVEVLKSH EETGKIHTSP LKNVAESPAE PPVKSEVMPV STVTVHHVQS
960 970 980 990 1000
SPVVIHQSQH SSTLVNQAPN SPLTTSPTVA SPGLNRTTSA VSESTTVTTT
1010 1020 1030 1040 1050
VVQPMQAPLS PQVSVNGSTM QSLFIEELHN ATTRNRALSI EKAEKKWEEK
1060 1070 1080 1090 1100
RQNRDHYNGK EFEKLLEEAQ ANIMKSIPNL EMPPQATSPK VNVVEKEVTV
1110 1120 1130 1140 1150
ETLNPELDTE KPVKSPPPPP PRRSYLVGSG LSTRLGEISY VTRKDNIVAK
1160 1170 1180 1190 1200
ESSEDSSSPA TQPKVPKEDS ASPQSLGTVA PAKDDDDEEE GDRIMAELQV
1210 1220 1230 1240 1250
FQKCTYMDVN SNSHVEQSRN DTHTKDARPV ALIQSKEKKA SPSTSQTSRM
1260 1270 1280 1290 1300
PIPAATKSRP PGSVDKTSKP HKLQDQRQYR QANGSAKKAG GDYKATSPTL
1310 1320 1330 1340 1350
SASKIPAFSS TSGKGSSVSS GDSTNLPSPP TKASVPPSNP LSPQTGRPTH
1360 1370 1380 1390 1400
SASFIPSVSN GSLKFQNPTH TGKGHHLSFS IQTQNGRPNP LPPSPFSSPS
1410 1420 1430 1440
FSSPTSPTSL NQGVKSIRSI HTPSFTSYKS QNGSVSKSTP SSTITKEPS
Length:1,449
Mass (Da):158,882
Last modified:September 29, 2021 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8EACE835C45EED73
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G1KVZ5G1KVZ5_ANOCA
KIAA1217
KIAA1217
1,738Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A803SP69A0A803SP69_ANOCA
KIAA1217
KIAA1217
1,896Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A803SX67A0A803SX67_ANOCA
KIAA1217
KIAA1217
1,968Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A803TUA9A0A803TUA9_ANOCA
KIAA1217
KIAA1217
1,965Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A803TUL3A0A803TUL3_ANOCA
KIAA1217
KIAA1217
1,912Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A803TWE4A0A803TWE4_ANOCA
KIAA1217
KIAA1217
1,773Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000008685; ENSACAP00000008503; ENSACAG00000008655

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000008503

Genome annotation databases

EnsembliENSACAT00000008685; ENSACAP00000008503; ENSACAG00000008655

Phylogenomic databases

eggNOGiENOG502QQCT, Eukaryota
GeneTreeiENSGT00940000156098
HOGENOMiCLU_002507_1_1_1
InParanoidiG1KI23
TreeFamiTF332255

Gene expression databases

BgeeiENSACAG00000008656, Expressed in hemipenis and 14 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR022782, AIP3-like_C
IPR026725, Skt
PANTHERiPTHR22741:SF11, PTHR22741:SF11, 2 hits
PfamiView protein in Pfam
PF03915, AIP3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KI23_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KI23
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: September 29, 2021
Last modified: September 29, 2021
This is version 47 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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