UniProtKB - G1KHM0 (G1KHM0_ANOCA)
Protein
UBC core domain-containing protein
Gene
UBE2G2
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 89 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- identical protein binding Source: Ensembl
- ubiquitin conjugating enzyme activity Source: GO_Central
GO - Biological processi
- cellular response to interferon-beta Source: Ensembl
- negative regulation of retrograde protein transport, ER to cytosol Source: Ensembl
- protein K48-linked ubiquitination Source: Ensembl
- protein polyubiquitination Source: GO_Central
- ubiquitin-dependent ERAD pathway Source: GO_Central
- ubiquitin-dependent protein catabolic process Source: GO_Central
Keywordsi
Molecular function | TransferaseARBA annotation |
Biological process | Ubl conjugation pathwayUniRule annotationARBA annotation |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: UBC core domain-containing proteinInterPro annotation |
Gene namesi | Name:UBE2G2Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Endoplasmic reticulum
- endoplasmic reticulum Source: GO_Central
Other locations
- lipid droplet Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000008283, Expressed in skeletal muscle tissue and 15 other tissues |
Interactioni
GO - Molecular functioni
- identical protein binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000008145 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 7 – 152 | UBC coreInterPro annotationAdd BLAST | 146 |
Sequence similaritiesi
Belongs to the ubiquitin-conjugating enzyme family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0426, Eukaryota |
GeneTreei | ENSGT00940000158193 |
HOGENOMi | CLU_030988_10_1_1 |
InParanoidi | G1KHM0 |
OMAi | PNMYESS |
TreeFami | TF101118 |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KHM0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGTALKRLM AEYKQLTLNP PEGIVAGPMN EENFFEWEAL IMGPEDTCFE
60 70 80 90 100
YGVFPAILSF PLDYPLSPPK MRFTCEMFHP NIYPDGRVCI SILHAPGDDP
110 120 130 140 150
MGYESSAERW SPVQSVEILL SVVSMLAEPN DESGANVDAS KMWREDREQF
160
NKIAKQIVQK SLGL
Genome annotation databases
Ensembli | ENSACAT00000008318; ENSACAP00000008145; ENSACAG00000008283 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000008145 |
Genome annotation databases
Ensembli | ENSACAT00000008318; ENSACAP00000008145; ENSACAG00000008283 |
Phylogenomic databases
eggNOGi | KOG0426, Eukaryota |
GeneTreei | ENSGT00940000158193 |
HOGENOMi | CLU_030988_10_1_1 |
InParanoidi | G1KHM0 |
OMAi | PNMYESS |
TreeFami | TF101118 |
Gene expression databases
Bgeei | ENSACAG00000008283, Expressed in skeletal muscle tissue and 15 other tissues |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KHM0_ANOCA | |
Accessioni | G1KHM0Primary (citable) accession number: G1KHM0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | October 7, 2020 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |