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UniProtKB - G1KGB6 (G1KGB6_ANOCA)

Entry version 50 (02 Dec 2020)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

TAB3

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TAB3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000007257, Expressed in forelimb bud and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000007096

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 51CUEInterPro annotationAdd BLAST44
Domaini653 – 683RanBP2-typeInterPro annotationAdd BLAST31

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni138 – 183DisorderedSequence analysisAdd BLAST46
Regioni211 – 359DisorderedSequence analysisAdd BLAST149
Regioni374 – 431DisorderedSequence analysisAdd BLAST58
Regioni480 – 514DisorderedSequence analysisAdd BLAST35
Regioni624 – 651DisorderedSequence analysisAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili524 – 558Sequence analysisAdd BLAST35
Coiled coili586 – 606Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi225 – 254PolarSequence analysisAdd BLAST30
Compositional biasi268 – 286PolarSequence analysisAdd BLAST19
Compositional biasi287 – 301Pro-richSequence analysisAdd BLAST15
Compositional biasi302 – 326PolarSequence analysisAdd BLAST25
Compositional biasi334 – 348PolarSequence analysisAdd BLAST15
Compositional biasi379 – 431PolarSequence analysisAdd BLAST53
Compositional biasi634 – 651PolyampholyteSequence analysisAdd BLAST18

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QVTR, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159499

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_025065_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		G1KGB6

Database of Orthologous Groups

More...OrthoDBi		324984at2759

TreeFam database of animal gene trees

More...TreeFami		TF332021

Family and domain databases

Conserved Domains Database

More...CDDi		cd14362, CUE_TAB2_TAB3, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003892, CUE
IPR041911, TAB2/3_CUE
IPR001876, Znf_RanBP2
IPR036443, Znf_RanBP2_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02845, CUE, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00546, CUE, 1 hit
SM00547, ZnF_RBZ, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF90209, SSF90209, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51140, CUE, 1 hit
PS01358, ZF_RANBP2_1, 1 hit
PS50199, ZF_RANBP2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KGB6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQGSPQLDM QVLHDLRQRF PEIPEGVVSQ CMLQNNNNLD ACCRVLAQES 
        60         70         80         90        100
NKYLYMEYHS PDDTRMNKNR LLHINLGIHP HASYHGGDGA QLNGGRTLVH 
       110        120        130        140        150
SSSDGHIDPQ RTGGKQLICL VQEPHSAPAV VAASPNYNPF FMNDQNRNAA 
       160        170        180        190        200
TPPPQPPQQP SSMQPGMSTS AMQGPPPPPT YMHIPRYSTN PITVTVSQNL 
       210        220        230        240        250
SSGQTVPRAL QILPPIPGNP YANPGSLYIR QTSQSSSGRQ TPTQSAQWHH 
       260        270        280        290        300
SSPQGPVPHY SPHPLPVYPH QQNYQPSQYS PKQPQIPQSP FRSPPTSQCP 
       310        320        330        340        350
SPFGSPQHQV QPTQLGHQSS HVFMPPSPST VLPHPYQQTP QTYQKPGGHS 
       360        370        380        390        400
VSYLPYGGSS LSKGSMNKIE ITVEPPQRPG TAMNRSPSPI GSQPSQRNQH 
       410        420        430        440        450
PLYAPGTPPS SSPSRSMSSQ PKPPYSVNPV YITYTQPTGS AGVLTQSPRV 
       460        470        480        490        500
MVSQPNPAVF KITVGRAPAE NLLNLVDQEE RSAAPEPIQP ISVVPGSGGE 
       510        520        530        540        550
RGSHKYQRSS SSGSDDYAYT QALLLHQRAR MERLAKELKF ENEELEKLKG 
       560        570        580        590        600
EVNGMEHDLM QRRLRRVSCT TSIPTPEEMT RLRSVNRQLQ INVDCTQKEI 
       610        620        630        640        650
DLLQSRGKFD PKAMSNFYDN LEPGPVVPPK PCKKDHQSSS KQALRTQPRD 
       660        670        680        690 
EDFEGAPWNC DSCTFLNHPA LNRCEQCEMP RFCLALLSAA IANKL
Length:695
Mass (Da):76,605
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE01BBDD8A69DC3D
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_008105570.1, XM_008107363.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000007249; ENSACAP00000007096; ENSACAG00000007257

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100558078

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_008105570.1, XM_008107363.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000007096

Genome annotation databases

EnsembliENSACAT00000007249; ENSACAP00000007096; ENSACAG00000007257
GeneIDi100558078

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		257397

Phylogenomic databases

eggNOGiENOG502QVTR, Eukaryota
GeneTreeiENSGT00940000159499
HOGENOMiCLU_025065_1_0_1
InParanoidiG1KGB6
OrthoDBi324984at2759
TreeFamiTF332021

Gene expression databases

BgeeiENSACAG00000007257, Expressed in forelimb bud and 14 other tissues

Family and domain databases

CDDicd14362, CUE_TAB2_TAB3, 1 hit
InterProiView protein in InterPro
IPR003892, CUE
IPR041911, TAB2/3_CUE
IPR001876, Znf_RanBP2
IPR036443, Znf_RanBP2_sf
PfamiView protein in Pfam
PF02845, CUE, 1 hit
SMARTiView protein in SMART
SM00546, CUE, 1 hit
SM00547, ZnF_RBZ, 1 hit
SUPFAMiSSF90209, SSF90209, 1 hit
PROSITEiView protein in PROSITE
PS51140, CUE, 1 hit
PS01358, ZF_RANBP2_1, 1 hit
PS50199, ZF_RANBP2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KGB6_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KGB6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: December 2, 2020
This is version 50 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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