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Entry version 61 (12 Aug 2020)
Sequence version 1 (19 Oct 2011)
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Protein
Submitted name:

Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

Gene

OBSCN

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEFImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OBSCNImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000006865, Expressed in skeletal muscle tissue and 2 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000006708

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 100Ig-likeInterPro annotationAdd BLAST91
Domaini110 – 201Ig-likeInterPro annotationAdd BLAST92
Domaini226 – 335Ig-likeInterPro annotationAdd BLAST110
Domaini339 – 422Ig-likeInterPro annotationAdd BLAST84
Domaini523 – 618Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini706 – 791Ig-likeInterPro annotationAdd BLAST86
Domaini956 – 1048Ig-likeInterPro annotationAdd BLAST93
Domaini1054 – 1145Ig-likeInterPro annotationAdd BLAST92
Domaini1153 – 1241Ig-likeInterPro annotationAdd BLAST89
Domaini1248 – 1335Ig-likeInterPro annotationAdd BLAST88
Domaini1347 – 1417Ig-likeInterPro annotationAdd BLAST71
Domaini1431 – 1514Ig-likeInterPro annotationAdd BLAST84
Domaini1529 – 1618Ig-likeInterPro annotationAdd BLAST90
Domaini1620 – 1708Ig-likeInterPro annotationAdd BLAST89
Domaini1712 – 1798Ig-likeInterPro annotationAdd BLAST87
Domaini1805 – 1889Ig-likeInterPro annotationAdd BLAST85
Domaini1893 – 1979Ig-likeInterPro annotationAdd BLAST87
Domaini1984 – 2068Ig-likeInterPro annotationAdd BLAST85
Domaini2162 – 2248Ig-likeInterPro annotationAdd BLAST87
Domaini2286 – 2377Ig-likeInterPro annotationAdd BLAST92
Domaini2464 – 2549Ig-likeInterPro annotationAdd BLAST86
Domaini2644 – 2728Ig-likeInterPro annotationAdd BLAST85
Domaini2823 – 2907Ig-likeInterPro annotationAdd BLAST85
Domaini2924 – 2996Ig-likeInterPro annotationAdd BLAST73
Domaini3008 – 3091Ig-likeInterPro annotationAdd BLAST84
Domaini3096 – 3180Ig-likeInterPro annotationAdd BLAST85
Domaini3185 – 3268Ig-likeInterPro annotationAdd BLAST84
Domaini3273 – 3357Ig-likeInterPro annotationAdd BLAST85
Domaini3362 – 3445Ig-likeInterPro annotationAdd BLAST84
Domaini3450 – 3534Ig-likeInterPro annotationAdd BLAST85
Domaini3539 – 3623Ig-likeInterPro annotationAdd BLAST85
Domaini3628 – 3711Ig-likeInterPro annotationAdd BLAST84
Domaini3717 – 3800Ig-likeInterPro annotationAdd BLAST84
Domaini3805 – 3888Ig-likeInterPro annotationAdd BLAST84
Domaini3893 – 3976Ig-likeInterPro annotationAdd BLAST84
Domaini3981 – 4062Ig-likeInterPro annotationAdd BLAST82
Domaini4070 – 4153Ig-likeInterPro annotationAdd BLAST84
Domaini4248 – 4334Ig-likeInterPro annotationAdd BLAST87
Domaini4337 – 4464Ig-likeInterPro annotationAdd BLAST128
Domaini4523 – 4618Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini4619 – 4706Ig-likeInterPro annotationAdd BLAST88
Domaini4896 – 4985Ig-likeInterPro annotationAdd BLAST90
Domaini5143 – 5232Ig-likeInterPro annotationAdd BLAST90
Domaini5275 – 5364Ig-likeInterPro annotationAdd BLAST90
Domaini5384 – 5479Ig-likeInterPro annotationAdd BLAST96

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni4702 – 4730DisorderedSequence analysisAdd BLAST29
Regioni4746 – 4779DisorderedSequence analysisAdd BLAST34
Regioni4842 – 4865DisorderedSequence analysisAdd BLAST24
Regioni4980 – 5017DisorderedSequence analysisAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1429 – 1470Sequence analysisAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi4746 – 4776PolyampholyteSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, Immunoglobulin domainARBA annotation, RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0613, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154756

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_223588_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1KFT9

Identification of Orthologs from Complete Genome Data

More...
OMAi
KYEFRVM

TreeFam database of animal gene trees

More...
TreeFami
TF331962

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 53 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR013106, Ig_V-set
IPR000048, IQ_motif_EF-hand-BS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041, fn3, 2 hits
PF07679, I-set, 47 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060, FN3, 2 hits
SM00409, IG, 51 hits
SM00408, IGc2, 45 hits
SM00406, IGv, 9 hits
SM00015, IQ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 51 hits
SSF49265, SSF49265, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 2 hits
PS50835, IG_LIKE, 43 hits
PS50096, IQ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KFT9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDYSSYSGVP RFLTRPKAFA VSMGKDATLS CQIMGNPIPM VSWEKDKFPI
60 70 80 90 100
QTGGRFKMVE DGDLYRLTIY DLNLEDSGQY ICRAKNTIGE AFAAVSIKVG
110 120 130 140 150
EQTTVTEQAP YFIQKPTSIR VIMGEDAMFK CIVQGSPPLS VNWEKDGRNL
160 170 180 190 200
GGRSESNRIQ IQSQGEKNAL KIQSTRLDDT GTYTCRAANP LGATSAAASL
210 220 230 240 250
VVDTADSYSP GGTRHAIDVG NSKTSPLLTH LQKRREEIRL RGDGGSYYGV
260 270 280 290 300
TTRTFTVTEG KHAKMSCYVT GEPKPEIVWK KDGEVILEGR RHIIYEDEQE
310 320 330 340 350
NFVLKILFCK QVDNGLYTCT ASNLAGQTYS SVLVTVKEPR IPFKTKLRDL
360 370 380 390 400
EVREKELAIF QCEVPAATTE TTWFKEETKL QQSNKYNIEE EGTHRKLTVQ
410 420 430 440 450
NVTMDDDAVY ICEMKEGSRT IAELSVQGNI IKKLPRKTAV SVNDTAIFCV
460 470 480 490 500
ELENKCQKSR WLKDKEELKS NSRISFTASK KEHSMIIRDC KMEDAGEIVF
510 520 530 540 550
VADDCRTSTQ FTVSAPKKPP SHPPLDPVVK NKTETSVTLA WSPPKMERPI
560 570 580 590 600
PIDGYLVERK KMTGFTWLKC HDSPIPETEF TLSNPPEEAD YFFRVSAVNS
610 620 630 640 650
YGQSDSLEFP GTLHLEPVLA VRSPLRNAEV NPGRDATFTV DLTNTCSGSW
660 670 680 690 700
FINGNPVQNS DKYIITRTKT THSLIVKRVT SAFKEAEVKF VTNNNIESTA
710 720 730 740 750
KIKLKDEVAN FANDSVPGIS VKLSEKFELV CEVSSITEGV IWKKGKKDIK
760 770 780 790 800
PDQRVTFAAE GLQRKLVVKS AVKQDEGIYS CETMSDKLTF QVEVKGEHGP
810 820 830 840 850
DPFPLPPSYG RCFQWSGVSI GTQNLKFLKN ALANHPNLFK STGAIYQSES
860 870 880 890 900
TFNQGEGLAK VFFGNKGSEP GTLPDNPKKI QLLLGKEEGV PLSLHCSQTQ
910 920 930 940 950
AGLLVSQPGT LSDNPKPSLG KSCISHTSLY KIQLLLGLAL SPSLNPFCCL
960 970 980 990 1000
LIFHFPFLSA EPEDVFANKE KVQKEVKVVL SENACLSCEM SQADTELRWY
1010 1020 1030 1040 1050
KDGRQIRSSQ KFKIESEGKS RRLIVQQVER KDAGEYTCEA AGQPLTFTLI
1060 1070 1080 1090 1100
ATSPKVVEAE EMFVNKEKIQ KEVKTSLSEN ATLSCEVSQT QTEVKWFKEG
1110 1120 1130 1140 1150
KLITSSKKFK VETEGRSRQL IVQQVEKKDA GEYTCEAAGQ KLTFKVMVEG
1160 1170 1180 1190 1200
SEPEDVFVNK EKVQKEVKAV SSKDAILSCE VSQAKSEVKW FKDGKPLTPG
1210 1220 1230 1240 1250
KKLKIEDEGK SRRLIVQATD KKDAGEYTCE VGNQKLTFKV TVADAEVEEI
1260 1270 1280 1290 1300
FANKEKVIKE VKATLSENTS FSCEVAQDKT DVKWFKDGKV ITASNKFKME
1310 1320 1330 1340 1350
TEGKNRKLVV QQVEKKDAGE YTCEAGGQKQ AFKLTVSEAE DAFVNKEKVQ
1360 1370 1380 1390 1400
KEVKVVTSKE ATLSCEVAQA KTEVKWFKDG KLITSSKKHK VEAEGKSRRL
1410 1420 1430 1440 1450
IVQATDKKDV GEYTCEAGSQ KLIFKVTVAD EKVAEVEEIF ANKEKIQKEI
1460 1470 1480 1490 1500
KAASSENATL SCEVAQAKAE VKWFKDGKLI TASKKFKVES EGKSRRLIVQ
1510 1520 1530 1540 1550
QVEKKDAGEY TCEAAGQKLA FKVIITEAEE VFTHKEMVQK EIQAVFSKDV
1560 1570 1580 1590 1600
TFSCEVAQAK TEVKWFKDGK LITSSKKHKV EAEGKSRRLI VQAAEKKDVG
1610 1620 1630 1640 1650
EYTCEAGNQK LTFKLNVTEP VEIFANKEKV QKEVKAVVKE ETVLSCEVAN
1660 1670 1680 1690 1700
SDTEVKWYKD GKLLSSNKKV KMESKGTSRK LVLEQVEKKD AGAYTCEAAG
1710 1720 1730 1740 1750
QKLTFKVEAV EPEAKFQRKP ALEEKIVVQE QKSVVLSTSV VPDNVEVKWF
1760 1770 1780 1790 1800
KDGIEIKDNK KYEMKKDGAS RTLTVKQADV KDIGVYTCET KSDKQQFQVQ
1810 1820 1830 1840 1850
VQEVPVKFAK KLEPVKAEIG GSLTLSCELS QTKGDVVWRK DGVELKADKR
1860 1870 1880 1890 1900
CQMREIGEKR VLTIAGLRAE DKGSYCCETK DDKCSIQVTP IVPRVVKFVK
1910 1920 1930 1940 1950
GLHNIVGEEG KEAFFKCVVS PNDAAVTWSC NGNKIEASKK YNIFQKDSNH
1960 1970 1980 1990 2000
SLTITDLSLE DSGEITADAE GVQSKANLKV EEAPALFVKK LEAKTVEEKE
2010 2020 2030 2040 2050
TVTLEVELSK ATTEVKWVKN GSLLHSDANM EIKAEGTKHS LVIKSAACGD
2060 2070 2080 2090 2100
RGFYACETLH DKTQAKLTVE MRPIKVVKGL QPMDVHEKEA VTFEVELSHE
2110 2120 2130 2140 2150
NVEGTWMKDG LRLKPKENCL ISAKGKKHSL TLSKLAMEDS GLIAFKAEGV
2160 2170 2180 2190 2200
HTTGRLNVKE SPVKIIKPLV DLKAQHKDEV TFECELSRAN AEVKWRKDGV
2210 2220 2230 2240 2250
ELRPNKRIVM GARGTKRSLT IHKCEYEDRG KYMCDADDDK SIADLEIQGK
2260 2270 2280 2290 2300
SYQLVYRSVE VEDSAEIKFV AETAESRAKL KVKELPVRFV KPLRVRIAIE
2310 2320 2330 2340 2350
KHRGFLECQV SRANAEVKWY KDNKEIHPGQ KYEMVSDGVY RKLLINEAEF
2360 2370 2380 2390 2400
EDEGIYTCDA IDEKSSAQFY VEEQSINIVK ELKDVEVIEP AEARFECEIS
2410 2420 2430 2440 2450
IQSVKPPKWS LRGEVLQASK DILIEQEGKI HRLILRKTDV DMTGTIQLAI
2460 2470 2480 2490 2500
GKSKSSANLV VKDLQVTITR QLEDKVVMET HSVVLSCDFK PSPKTVEWYR
2510 2520 2530 2540 2550
DHTLIEASER FKIKREKYSA ELKILKLNVG DSGVYKCKAG STETKATLTV
2560 2570 2580 2590 2600
LERKVEITKH LQDVETEEES CAAFSCELSE DSDDVEWFLN DTHLFPNNFN
2610 2620 2630 2640 2650
EIKSLGKVHS LTLKHVMPED SGMVTIKVNK KVTESARLKV KEKPAVFMKS
2660 2670 2680 2690 2700
LDDVVGEERG TITLECEVSK TKVKPIWKKE GLELTPGEKY EMLQAGKTLG
2710 2720 2730 2740 2750
LVIHDLSKSD AGLYTCDLGT EVAKSKVNIQ ELNVGITKRL KNTEVLEGES
2760 2770 2780 2790 2800
CTFECVLSHE SVEDCHWLLN GTEVGHEGRF RAFNKGRKYT LNIKKALPSD
2810 2820 2830 2840 2850
AGEVVFSGRD LNSKALLVVK EKPAEFTKKL EDKTTVVGQE VSLSCDMSKW
2860 2870 2880 2890 2900
DSNVKWCKEG KEIRRSQKYD IRQEGTRAIL IIHDASVKDS GEYTCETEIS
2910 2920 2930 2940 2950
KTKARLTVEE AGNCFIKDLS DLKIEENKKA VFTCETKKPA STVTWRKGIT
2960 2970 2980 2990 3000
DLKASKKCEI SQKGNVLQLT VNDLVESDSD IYTCDIGDTQ SSAKLVVQGR
3010 3020 3030 3040 3050
KCHLVSLSRA EQELQNREAK EGSKVRLSCE LNKPDLPVQW MKGSEVLQAS
3060 3070 3080 3090 3100
DKYELKQRGS VAELVIRDAK AADAGEYTCA VGEVKTSARV EVMAAPVIFK
3110 3120 3130 3140 3150
EELRDTEKEE GEVVALRCVL ATPDVPVSWK KGATVLRASE KYEMKKEGCV
3160 3170 3180 3190 3200
AELIIHDVET EDAGRYSCDT GEQQSTAQVK VHATPVRFKE ALKNTEATQG
3210 3220 3230 3240 3250
GVVTLRCELN KPAPVEWRKG QKGLRPSSKY RMKKEGPVVE LIVHDLDLKD
3260 3270 3280 3290 3300
AGDYSCTVGD QKTTAVLTVN ALPAQFKTQL KNEEATESGT ATLQCELTKA
3310 3320 3330 3340 3350
VDSIEWMKEQ KVLEPSDKYR MRLEGRFAEL TIQDLEPADA GSYTCVCGDL
3360 3370 3380 3390 3400
KTTATLKVNA LPVFFQEELK SSEVAEGETV TFHCRLSKAS PVEWQKGPKA
3410 3420 3430 3440 3450
LKAGGRYKIR QDGPNAELVI HDLVVADAGD YSCKCGNQKT TANLTVNVLP
3460 3470 3480 3490 3500
VLFTKPLKDQ EATEGKDVTL QCELNKASSA VEWKKGHKTL KPGSKYKMRQ
3510 3520 3530 3540 3550
DGAVAELVIQ GLDVTDSGSY SCVCGGEQTT ASLEVKALPV LFKEGLKNRE
3560 3570 3580 3590 3600
AVEGTTATLH CEMTRAGAEV EWRKGTQALK PSNKYRMRQE GAAAELLIRD
3610 3620 3630 3640 3650
LQAEDTGEFA CLCGDQKTTA VLTVHAVPAH FQEELKSKEA TEGETAVLRC
3660 3670 3680 3690 3700
ELNKVSSVEW RKAGQPLKTD DRHKIKQKDR VAELAIHNVT EQDAGDYSCI
3710 3720 3730 3740 3750
CGDQKTSASL TVHALPPRFK TELRNLEAAE GGTATLHCEL TKVAAPVEWK
3760 3770 3780 3790 3800
KGSEVLQPSA KYEMKLEGVV AELVVHDLEL ADGGEYSCMF GGQKTSASLK
3810 3820 3830 3840 3850
VNALPAQFKK GLENQEALED RTATFQCELT KPSPVEWKKK HKLLKPSDKY
3860 3870 3880 3890 3900
KMRQEGILSE LVISSLEPKD AGDYCCVCGD QKTSAALTVH AVPAFFKEEL
3910 3920 3930 3940 3950
KSTEATEGET ATMRCKLSKE STVQWKKGDQ SLKPNEKYIM RQKDTVVELV
3960 3970 3980 3990 4000
IQNLEEEDAG DYACVCGNEQ TTAALAVHAL PARFKCNLKN MDATEGGVAT
4010 4020 4030 4040 4050
LCCELTRVAL VQWKKEHQVL QAGEKYVMKQ DGTSVELVIH QLNLQDTGSY
4060 4070 4080 4090 4100
TCTCGDEQTT ASLRVNALKP EFKQPLKNEK AEEGGTAKFR CDLTVLKAPV
4110 4120 4130 4140 4150
EWKKDGVALH PGHKYEMRQE GTRCELLICD VEPKDRGEYS CITGDQTTSA
4160 4170 4180 4190 4200
TLTVKELDIT ITKGLKNVEV FEDEDVAFEC KVSHDNARDV EWKLQEASLQ
4210 4220 4230 4240 4250
SNEMNEISVE KGRIHTLRLK KVTQQDSGTV TFRVGPYTST AQLTVKEPPV
4260 4270 4280 4290 4300
TIVEALKDIT LYEDEDAVFQ CKVSQEKAKD VEWTLAGAPL QSNEMNEIAV
4310 4320 4330 4340 4350
QGKVHSLTLR KVALEDSGAV SFRVGQNSSE ARLTVQPKNT IIQGLENVDA
4360 4370 4380 4390 4400
MEGGEALFEC YLSKPECYNY NWLIDDEPAK TSENTEMVYF ENGLRHLLLL
4410 4420 4430 4440 4450
KNLTLQDSCR VTFQASDVVT SAFLTVKGWR LEFLQPLTDT TVTAGDQAVF
4460 4470 4480 4490 4500
TCVLSEAVPV HEVAWYINDV DIQPDETWAI QAEGNTYTLI LKTAQPHHSG
4510 4520 4530 4540 4550
EVTFAARDAI ASAKISIIAL PDPPEEPEIL SKTSHSVTLS WFKPLNNGGS
4560 4570 4580 4590 4600
DILGYQVERK SPGSDWQPCH TGVIPSTEFV ADGLTAGQTY RFRISAVSKA
4610 4620 4630 4640 4650
GAGKPVHLPQ SVQLVHPVPE AISITRPLVD KSAMEGEKTR LECELSSEAQ
4660 4670 4680 4690 4700
DVAWFKGKEP VQPGGRYEII SEGRKQTLVI HNFKPEDQGS YTCMASPDVK
4710 4720 4730 4740 4750
TSASLSAEAL GEAEDEQTQP SLPPEAAQEG DLHLLWEALA KKRRMSREPT
4760 4770 4780 4790 4800
LDSISELPEE DDKLQKRKKE EAEMGQYYSE DYSTCDESAK AGEADFSLTS
4810 4820 4830 4840 4850
SDDESRSGTP SLITYLKKAG TTGASITTKV QTISTEKIYK QWEKTGTEAP
4860 4870 4880 4890 4900
PQAKPTEPEA MEGDLDDPSM AQAAVKIQAA FKGYKVRKEI KQQECPVFVE
4910 4920 4930 4940 4950
TFKDFFGEPG GNLHFECVAQ SKTDMKVRWL KDGSEIFDGR HYHIDIYSDG
4960 4970 4980 4990 5000
TFSLIITGLE MDDMGKYTCE VSNKFGSVSH SAKVTVKPPP QVPVRKHKPA
5010 5020 5030 5040 5050
KKLPESETES SSGSELDDAF RKAGRRLHKL FKSKISTEIS DVEEELFVSA
5060 5070 5080 5090 5100
DEGEIEVVDH QTYREDERYI YIKFEVMFEA KTAANRFREM FAAMGIPVEI
5110 5120 5130 5140 5150
DILDQGPKKI ELRIGKATPP APGQLKSLVK RPPPPLLTSD TAPVFITELQ
5160 5170 5180 5190 5200
NQEVQDGYPV SFDCVVIGKP IPTVRWFKDG RVIEEDDHYM INEDQEGCHQ
5210 5220 5230 5240 5250
LIITAVVPLD MGVYRCLAEN SMGVSSTKAE LRVDLTSTDY DTAATETSSY
5260 5270 5280 5290 5300
YSAKGYLSSR EQEGVESMTE EEQLPQILDE LHDIHVAPGA LFAKFHLKVK
5310 5320 5330 5340 5350
GYPEPRLYWF KDGQPLHVSQ RLLKTDKREF HSLEILNVTK EDAGEYSVFI
5360 5370 5380 5390 5400
SNSAGSAYSA ARLVVKEPYE EEETRKDIEQ LVPPRFLERF TNKKVKTGVS
5410 5420 5430 5440 5450
ITLSVKVEGS PPPSVTWLKE ESDGEDILWI KPDTPGYKLA SSNMHHSLIL
5460 5470 5480 5490 5500
LDVKKGYNGN YTCIASNQAG QSICSATLEV VDGIVGVEVQ NTCRAEVCPC
5510 5520 5530 5540 5550
LTQSHFKCSD AQGMNLGEAP ALFGKEGMEP RDGEAARSHI SLTEVGTEEF

LQKL
Length:5,554
Mass (Da):617,797
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4B65EF7FAB0493F6
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSACAT00000006854; ENSACAP00000006708; ENSACAG00000006865

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000006708

Genome annotation databases

EnsembliENSACAT00000006854; ENSACAP00000006708; ENSACAG00000006865

Phylogenomic databases

eggNOGiKOG0613, Eukaryota
GeneTreeiENSGT00940000154756
HOGENOMiCLU_223588_0_0_1
InParanoidiG1KFT9
OMAiKYEFRVM
TreeFamiTF331962

Gene expression databases

BgeeiENSACAG00000006865, Expressed in skeletal muscle tissue and 2 other tissues

Family and domain databases

CDDicd00063, FN3, 2 hits
Gene3Di2.60.40.10, 53 hits
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR013106, Ig_V-set
IPR000048, IQ_motif_EF-hand-BS
PfamiView protein in Pfam
PF00041, fn3, 2 hits
PF07679, I-set, 47 hits
SMARTiView protein in SMART
SM00060, FN3, 2 hits
SM00409, IG, 51 hits
SM00408, IGc2, 45 hits
SM00406, IGv, 9 hits
SM00015, IQ, 1 hit
SUPFAMiSSF48726, SSF48726, 51 hits
SSF49265, SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 2 hits
PS50835, IG_LIKE, 43 hits
PS50096, IQ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KFT9_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KFT9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: August 12, 2020
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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