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UniProtKB - G1KFT9 (G1KFT9_ANOCA)

Entry version 61 (12 Aug 2020)
Sequence version 1 (19 Oct 2011)
Previous versions | rss
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Protein
Submitted name:

Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

Gene

OBSCN

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEFImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OBSCNImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000006865, Expressed in skeletal muscle tissue and 2 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000006708

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 100Ig-likeInterPro annotationAdd BLAST91
Domaini110 – 201Ig-likeInterPro annotationAdd BLAST92
Domaini226 – 335Ig-likeInterPro annotationAdd BLAST110
Domaini339 – 422Ig-likeInterPro annotationAdd BLAST84
Domaini523 – 618Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini706 – 791Ig-likeInterPro annotationAdd BLAST86
Domaini956 – 1048Ig-likeInterPro annotationAdd BLAST93
Domaini1054 – 1145Ig-likeInterPro annotationAdd BLAST92
Domaini1153 – 1241Ig-likeInterPro annotationAdd BLAST89
Domaini1248 – 1335Ig-likeInterPro annotationAdd BLAST88
Domaini1347 – 1417Ig-likeInterPro annotationAdd BLAST71
Domaini1431 – 1514Ig-likeInterPro annotationAdd BLAST84
Domaini1529 – 1618Ig-likeInterPro annotationAdd BLAST90
Domaini1620 – 1708Ig-likeInterPro annotationAdd BLAST89
Domaini1712 – 1798Ig-likeInterPro annotationAdd BLAST87
Domaini1805 – 1889Ig-likeInterPro annotationAdd BLAST85
Domaini1893 – 1979Ig-likeInterPro annotationAdd BLAST87
Domaini1984 – 2068Ig-likeInterPro annotationAdd BLAST85
Domaini2162 – 2248Ig-likeInterPro annotationAdd BLAST87
Domaini2286 – 2377Ig-likeInterPro annotationAdd BLAST92
Domaini2464 – 2549Ig-likeInterPro annotationAdd BLAST86
Domaini2644 – 2728Ig-likeInterPro annotationAdd BLAST85
Domaini2823 – 2907Ig-likeInterPro annotationAdd BLAST85
Domaini2924 – 2996Ig-likeInterPro annotationAdd BLAST73
Domaini3008 – 3091Ig-likeInterPro annotationAdd BLAST84
Domaini3096 – 3180Ig-likeInterPro annotationAdd BLAST85
Domaini3185 – 3268Ig-likeInterPro annotationAdd BLAST84
Domaini3273 – 3357Ig-likeInterPro annotationAdd BLAST85
Domaini3362 – 3445Ig-likeInterPro annotationAdd BLAST84
Domaini3450 – 3534Ig-likeInterPro annotationAdd BLAST85
Domaini3539 – 3623Ig-likeInterPro annotationAdd BLAST85
Domaini3628 – 3711Ig-likeInterPro annotationAdd BLAST84
Domaini3717 – 3800Ig-likeInterPro annotationAdd BLAST84
Domaini3805 – 3888Ig-likeInterPro annotationAdd BLAST84
Domaini3893 – 3976Ig-likeInterPro annotationAdd BLAST84
Domaini3981 – 4062Ig-likeInterPro annotationAdd BLAST82
Domaini4070 – 4153Ig-likeInterPro annotationAdd BLAST84
Domaini4248 – 4334Ig-likeInterPro annotationAdd BLAST87
Domaini4337 – 4464Ig-likeInterPro annotationAdd BLAST128
Domaini4523 – 4618Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini4619 – 4706Ig-likeInterPro annotationAdd BLAST88
Domaini4896 – 4985Ig-likeInterPro annotationAdd BLAST90
Domaini5143 – 5232Ig-likeInterPro annotationAdd BLAST90
Domaini5275 – 5364Ig-likeInterPro annotationAdd BLAST90
Domaini5384 – 5479Ig-likeInterPro annotationAdd BLAST96

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni4702 – 4730DisorderedSequence analysisAdd BLAST29
Regioni4746 – 4779DisorderedSequence analysisAdd BLAST34
Regioni4842 – 4865DisorderedSequence analysisAdd BLAST24
Regioni4980 – 5017DisorderedSequence analysisAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1429 – 1470Sequence analysisAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi4746 – 4776PolyampholyteSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, Immunoglobulin domainARBA annotation, RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0613, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154756

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_223588_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		G1KFT9

Identification of Orthologs from Complete Genome Data

More...OMAi		KYEFRVM

TreeFam database of animal gene trees

More...TreeFami		TF331962

Family and domain databases

Conserved Domains Database

More...CDDi		cd00063, FN3, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 53 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR013106, Ig_V-set
IPR000048, IQ_motif_EF-hand-BS

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00041, fn3, 2 hits
PF07679, I-set, 47 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00060, FN3, 2 hits
SM00409, IG, 51 hits
SM00408, IGc2, 45 hits
SM00406, IGv, 9 hits
SM00015, IQ, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48726, SSF48726, 51 hits
SSF49265, SSF49265, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50853, FN3, 2 hits
PS50835, IG_LIKE, 43 hits
PS50096, IQ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KFT9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDYSSYSGVP RFLTRPKAFA VSMGKDATLS CQIMGNPIPM VSWEKDKFPI 
        60         70         80         90        100
QTGGRFKMVE DGDLYRLTIY DLNLEDSGQY ICRAKNTIGE AFAAVSIKVG 
       110        120        130        140        150
EQTTVTEQAP YFIQKPTSIR VIMGEDAMFK CIVQGSPPLS VNWEKDGRNL 
       160        170        180        190        200
GGRSESNRIQ IQSQGEKNAL KIQSTRLDDT GTYTCRAANP LGATSAAASL 
       210        220        230        240        250
VVDTADSYSP GGTRHAIDVG NSKTSPLLTH LQKRREEIRL RGDGGSYYGV 
       260        270        280        290        300
TTRTFTVTEG KHAKMSCYVT GEPKPEIVWK KDGEVILEGR RHIIYEDEQE 
       310        320        330        340        350
NFVLKILFCK QVDNGLYTCT ASNLAGQTYS SVLVTVKEPR IPFKTKLRDL 
       360        370        380        390        400
EVREKELAIF QCEVPAATTE TTWFKEETKL QQSNKYNIEE EGTHRKLTVQ 
       410        420        430        440        450
NVTMDDDAVY ICEMKEGSRT IAELSVQGNI IKKLPRKTAV SVNDTAIFCV 
       460        470        480        490        500
ELENKCQKSR WLKDKEELKS NSRISFTASK KEHSMIIRDC KMEDAGEIVF 
       510        520        530        540        550
VADDCRTSTQ FTVSAPKKPP SHPPLDPVVK NKTETSVTLA WSPPKMERPI 
       560        570        580        590        600
PIDGYLVERK KMTGFTWLKC HDSPIPETEF TLSNPPEEAD YFFRVSAVNS 
       610        620        630        640        650
YGQSDSLEFP GTLHLEPVLA VRSPLRNAEV NPGRDATFTV DLTNTCSGSW 
       660        670        680        690        700
FINGNPVQNS DKYIITRTKT THSLIVKRVT SAFKEAEVKF VTNNNIESTA 
       710        720        730        740        750
KIKLKDEVAN FANDSVPGIS VKLSEKFELV CEVSSITEGV IWKKGKKDIK 
       760        770        780        790        800
PDQRVTFAAE GLQRKLVVKS AVKQDEGIYS CETMSDKLTF QVEVKGEHGP 
       810        820        830        840        850
DPFPLPPSYG RCFQWSGVSI GTQNLKFLKN ALANHPNLFK STGAIYQSES 
       860        870        880        890        900
TFNQGEGLAK VFFGNKGSEP GTLPDNPKKI QLLLGKEEGV PLSLHCSQTQ 
       910        920        930        940        950
AGLLVSQPGT LSDNPKPSLG KSCISHTSLY KIQLLLGLAL SPSLNPFCCL 
       960        970        980        990       1000
LIFHFPFLSA EPEDVFANKE KVQKEVKVVL SENACLSCEM SQADTELRWY 
      1010       1020       1030       1040       1050
KDGRQIRSSQ KFKIESEGKS RRLIVQQVER KDAGEYTCEA AGQPLTFTLI 
      1060       1070       1080       1090       1100
ATSPKVVEAE EMFVNKEKIQ KEVKTSLSEN ATLSCEVSQT QTEVKWFKEG 
      1110       1120       1130       1140       1150
KLITSSKKFK VETEGRSRQL IVQQVEKKDA GEYTCEAAGQ KLTFKVMVEG 
      1160       1170       1180       1190       1200
SEPEDVFVNK EKVQKEVKAV SSKDAILSCE VSQAKSEVKW FKDGKPLTPG 
      1210       1220       1230       1240       1250
KKLKIEDEGK SRRLIVQATD KKDAGEYTCE VGNQKLTFKV TVADAEVEEI 
      1260       1270       1280       1290       1300
FANKEKVIKE VKATLSENTS FSCEVAQDKT DVKWFKDGKV ITASNKFKME 
      1310       1320       1330       1340       1350
TEGKNRKLVV QQVEKKDAGE YTCEAGGQKQ AFKLTVSEAE DAFVNKEKVQ 
      1360       1370       1380       1390       1400
KEVKVVTSKE ATLSCEVAQA KTEVKWFKDG KLITSSKKHK VEAEGKSRRL 
      1410       1420       1430       1440       1450
IVQATDKKDV GEYTCEAGSQ KLIFKVTVAD EKVAEVEEIF ANKEKIQKEI 
      1460       1470       1480       1490       1500
KAASSENATL SCEVAQAKAE VKWFKDGKLI TASKKFKVES EGKSRRLIVQ 
      1510       1520       1530       1540       1550
QVEKKDAGEY TCEAAGQKLA FKVIITEAEE VFTHKEMVQK EIQAVFSKDV 
      1560       1570       1580       1590       1600
TFSCEVAQAK TEVKWFKDGK LITSSKKHKV EAEGKSRRLI VQAAEKKDVG 
      1610       1620       1630       1640       1650
EYTCEAGNQK LTFKLNVTEP VEIFANKEKV QKEVKAVVKE ETVLSCEVAN 
      1660       1670       1680       1690       1700
SDTEVKWYKD GKLLSSNKKV KMESKGTSRK LVLEQVEKKD AGAYTCEAAG 
      1710       1720       1730       1740       1750
QKLTFKVEAV EPEAKFQRKP ALEEKIVVQE QKSVVLSTSV VPDNVEVKWF 
      1760       1770       1780       1790       1800
KDGIEIKDNK KYEMKKDGAS RTLTVKQADV KDIGVYTCET KSDKQQFQVQ 
      1810       1820       1830       1840       1850
VQEVPVKFAK KLEPVKAEIG GSLTLSCELS QTKGDVVWRK DGVELKADKR 
      1860       1870       1880       1890       1900
CQMREIGEKR VLTIAGLRAE DKGSYCCETK DDKCSIQVTP IVPRVVKFVK 
      1910       1920       1930       1940       1950
GLHNIVGEEG KEAFFKCVVS PNDAAVTWSC NGNKIEASKK YNIFQKDSNH 
      1960       1970       1980       1990       2000
SLTITDLSLE DSGEITADAE GVQSKANLKV EEAPALFVKK LEAKTVEEKE 
      2010       2020       2030       2040       2050
TVTLEVELSK ATTEVKWVKN GSLLHSDANM EIKAEGTKHS LVIKSAACGD 
      2060       2070       2080       2090       2100
RGFYACETLH DKTQAKLTVE MRPIKVVKGL QPMDVHEKEA VTFEVELSHE 
      2110       2120       2130       2140       2150
NVEGTWMKDG LRLKPKENCL ISAKGKKHSL TLSKLAMEDS GLIAFKAEGV 
      2160       2170       2180       2190       2200
HTTGRLNVKE SPVKIIKPLV DLKAQHKDEV TFECELSRAN AEVKWRKDGV 
      2210       2220       2230       2240       2250
ELRPNKRIVM GARGTKRSLT IHKCEYEDRG KYMCDADDDK SIADLEIQGK 
      2260       2270       2280       2290       2300
SYQLVYRSVE VEDSAEIKFV AETAESRAKL KVKELPVRFV KPLRVRIAIE 
      2310       2320       2330       2340       2350
KHRGFLECQV SRANAEVKWY KDNKEIHPGQ KYEMVSDGVY RKLLINEAEF 
      2360       2370       2380       2390       2400
EDEGIYTCDA IDEKSSAQFY VEEQSINIVK ELKDVEVIEP AEARFECEIS 
      2410       2420       2430       2440       2450
IQSVKPPKWS LRGEVLQASK DILIEQEGKI HRLILRKTDV DMTGTIQLAI 
      2460       2470       2480       2490       2500
GKSKSSANLV VKDLQVTITR QLEDKVVMET HSVVLSCDFK PSPKTVEWYR 
      2510       2520       2530       2540       2550
DHTLIEASER FKIKREKYSA ELKILKLNVG DSGVYKCKAG STETKATLTV 
      2560       2570       2580       2590       2600
LERKVEITKH LQDVETEEES CAAFSCELSE DSDDVEWFLN DTHLFPNNFN 
      2610       2620       2630       2640       2650
EIKSLGKVHS LTLKHVMPED SGMVTIKVNK KVTESARLKV KEKPAVFMKS 
      2660       2670       2680       2690       2700
LDDVVGEERG TITLECEVSK TKVKPIWKKE GLELTPGEKY EMLQAGKTLG 
      2710       2720       2730       2740       2750
LVIHDLSKSD AGLYTCDLGT EVAKSKVNIQ ELNVGITKRL KNTEVLEGES 
      2760       2770       2780       2790       2800
CTFECVLSHE SVEDCHWLLN GTEVGHEGRF RAFNKGRKYT LNIKKALPSD 
      2810       2820       2830       2840       2850
AGEVVFSGRD LNSKALLVVK EKPAEFTKKL EDKTTVVGQE VSLSCDMSKW 
      2860       2870       2880       2890       2900
DSNVKWCKEG KEIRRSQKYD IRQEGTRAIL IIHDASVKDS GEYTCETEIS 
      2910       2920       2930       2940       2950
KTKARLTVEE AGNCFIKDLS DLKIEENKKA VFTCETKKPA STVTWRKGIT 
      2960       2970       2980       2990       3000
DLKASKKCEI SQKGNVLQLT VNDLVESDSD IYTCDIGDTQ SSAKLVVQGR 
      3010       3020       3030       3040       3050
KCHLVSLSRA EQELQNREAK EGSKVRLSCE LNKPDLPVQW MKGSEVLQAS 
      3060       3070       3080       3090       3100
DKYELKQRGS VAELVIRDAK AADAGEYTCA VGEVKTSARV EVMAAPVIFK 
      3110       3120       3130       3140       3150
EELRDTEKEE GEVVALRCVL ATPDVPVSWK KGATVLRASE KYEMKKEGCV 
      3160       3170       3180       3190       3200
AELIIHDVET EDAGRYSCDT GEQQSTAQVK VHATPVRFKE ALKNTEATQG 
      3210       3220       3230       3240       3250
GVVTLRCELN KPAPVEWRKG QKGLRPSSKY RMKKEGPVVE LIVHDLDLKD 
      3260       3270       3280       3290       3300
AGDYSCTVGD QKTTAVLTVN ALPAQFKTQL KNEEATESGT ATLQCELTKA 
      3310       3320       3330       3340       3350
VDSIEWMKEQ KVLEPSDKYR MRLEGRFAEL TIQDLEPADA GSYTCVCGDL 
      3360       3370       3380       3390       3400
KTTATLKVNA LPVFFQEELK SSEVAEGETV TFHCRLSKAS PVEWQKGPKA 
      3410       3420       3430       3440       3450
LKAGGRYKIR QDGPNAELVI HDLVVADAGD YSCKCGNQKT TANLTVNVLP 
      3460       3470       3480       3490       3500
VLFTKPLKDQ EATEGKDVTL QCELNKASSA VEWKKGHKTL KPGSKYKMRQ 
      3510       3520       3530       3540       3550
DGAVAELVIQ GLDVTDSGSY SCVCGGEQTT ASLEVKALPV LFKEGLKNRE 
      3560       3570       3580       3590       3600
AVEGTTATLH CEMTRAGAEV EWRKGTQALK PSNKYRMRQE GAAAELLIRD 
      3610       3620       3630       3640       3650
LQAEDTGEFA CLCGDQKTTA VLTVHAVPAH FQEELKSKEA TEGETAVLRC 
      3660       3670       3680       3690       3700
ELNKVSSVEW RKAGQPLKTD DRHKIKQKDR VAELAIHNVT EQDAGDYSCI 
      3710       3720       3730       3740       3750
CGDQKTSASL TVHALPPRFK TELRNLEAAE GGTATLHCEL TKVAAPVEWK 
      3760       3770       3780       3790       3800
KGSEVLQPSA KYEMKLEGVV AELVVHDLEL ADGGEYSCMF GGQKTSASLK 
      3810       3820       3830       3840       3850
VNALPAQFKK GLENQEALED RTATFQCELT KPSPVEWKKK HKLLKPSDKY 
      3860       3870       3880       3890       3900
KMRQEGILSE LVISSLEPKD AGDYCCVCGD QKTSAALTVH AVPAFFKEEL 
      3910       3920       3930       3940       3950
KSTEATEGET ATMRCKLSKE STVQWKKGDQ SLKPNEKYIM RQKDTVVELV 
      3960       3970       3980       3990       4000
IQNLEEEDAG DYACVCGNEQ TTAALAVHAL PARFKCNLKN MDATEGGVAT 
      4010       4020       4030       4040       4050
LCCELTRVAL VQWKKEHQVL QAGEKYVMKQ DGTSVELVIH QLNLQDTGSY 
      4060       4070       4080       4090       4100
TCTCGDEQTT ASLRVNALKP EFKQPLKNEK AEEGGTAKFR CDLTVLKAPV 
      4110       4120       4130       4140       4150
EWKKDGVALH PGHKYEMRQE GTRCELLICD VEPKDRGEYS CITGDQTTSA 
      4160       4170       4180       4190       4200
TLTVKELDIT ITKGLKNVEV FEDEDVAFEC KVSHDNARDV EWKLQEASLQ 
      4210       4220       4230       4240       4250
SNEMNEISVE KGRIHTLRLK KVTQQDSGTV TFRVGPYTST AQLTVKEPPV 
      4260       4270       4280       4290       4300
TIVEALKDIT LYEDEDAVFQ CKVSQEKAKD VEWTLAGAPL QSNEMNEIAV 
      4310       4320       4330       4340       4350
QGKVHSLTLR KVALEDSGAV SFRVGQNSSE ARLTVQPKNT IIQGLENVDA 
      4360       4370       4380       4390       4400
MEGGEALFEC YLSKPECYNY NWLIDDEPAK TSENTEMVYF ENGLRHLLLL 
      4410       4420       4430       4440       4450
KNLTLQDSCR VTFQASDVVT SAFLTVKGWR LEFLQPLTDT TVTAGDQAVF 
      4460       4470       4480       4490       4500
TCVLSEAVPV HEVAWYINDV DIQPDETWAI QAEGNTYTLI LKTAQPHHSG 
      4510       4520       4530       4540       4550
EVTFAARDAI ASAKISIIAL PDPPEEPEIL SKTSHSVTLS WFKPLNNGGS 
      4560       4570       4580       4590       4600
DILGYQVERK SPGSDWQPCH TGVIPSTEFV ADGLTAGQTY RFRISAVSKA 
      4610       4620       4630       4640       4650
GAGKPVHLPQ SVQLVHPVPE AISITRPLVD KSAMEGEKTR LECELSSEAQ 
      4660       4670       4680       4690       4700
DVAWFKGKEP VQPGGRYEII SEGRKQTLVI HNFKPEDQGS YTCMASPDVK 
      4710       4720       4730       4740       4750
TSASLSAEAL GEAEDEQTQP SLPPEAAQEG DLHLLWEALA KKRRMSREPT 
      4760       4770       4780       4790       4800
LDSISELPEE DDKLQKRKKE EAEMGQYYSE DYSTCDESAK AGEADFSLTS 
      4810       4820       4830       4840       4850
SDDESRSGTP SLITYLKKAG TTGASITTKV QTISTEKIYK QWEKTGTEAP 
      4860       4870       4880       4890       4900
PQAKPTEPEA MEGDLDDPSM AQAAVKIQAA FKGYKVRKEI KQQECPVFVE 
      4910       4920       4930       4940       4950
TFKDFFGEPG GNLHFECVAQ SKTDMKVRWL KDGSEIFDGR HYHIDIYSDG 
      4960       4970       4980       4990       5000
TFSLIITGLE MDDMGKYTCE VSNKFGSVSH SAKVTVKPPP QVPVRKHKPA 
      5010       5020       5030       5040       5050
KKLPESETES SSGSELDDAF RKAGRRLHKL FKSKISTEIS DVEEELFVSA 
      5060       5070       5080       5090       5100
DEGEIEVVDH QTYREDERYI YIKFEVMFEA KTAANRFREM FAAMGIPVEI 
      5110       5120       5130       5140       5150
DILDQGPKKI ELRIGKATPP APGQLKSLVK RPPPPLLTSD TAPVFITELQ 
      5160       5170       5180       5190       5200
NQEVQDGYPV SFDCVVIGKP IPTVRWFKDG RVIEEDDHYM INEDQEGCHQ 
      5210       5220       5230       5240       5250
LIITAVVPLD MGVYRCLAEN SMGVSSTKAE LRVDLTSTDY DTAATETSSY 
      5260       5270       5280       5290       5300
YSAKGYLSSR EQEGVESMTE EEQLPQILDE LHDIHVAPGA LFAKFHLKVK 
      5310       5320       5330       5340       5350
GYPEPRLYWF KDGQPLHVSQ RLLKTDKREF HSLEILNVTK EDAGEYSVFI 
      5360       5370       5380       5390       5400
SNSAGSAYSA ARLVVKEPYE EEETRKDIEQ LVPPRFLERF TNKKVKTGVS 
      5410       5420       5430       5440       5450
ITLSVKVEGS PPPSVTWLKE ESDGEDILWI KPDTPGYKLA SSNMHHSLIL 
      5460       5470       5480       5490       5500
LDVKKGYNGN YTCIASNQAG QSICSATLEV VDGIVGVEVQ NTCRAEVCPC 
      5510       5520       5530       5540       5550
LTQSHFKCSD AQGMNLGEAP ALFGKEGMEP RDGEAARSHI SLTEVGTEEF 

LQKL
Length:5,554
Mass (Da):617,797
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4B65EF7FAB0493F6
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000006854; ENSACAP00000006708; ENSACAG00000006865

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000006708

Genome annotation databases

EnsembliENSACAT00000006854; ENSACAP00000006708; ENSACAG00000006865

Phylogenomic databases

eggNOGiKOG0613, Eukaryota
GeneTreeiENSGT00940000154756
HOGENOMiCLU_223588_0_0_1
InParanoidiG1KFT9
OMAiKYEFRVM
TreeFamiTF331962

Gene expression databases

BgeeiENSACAG00000006865, Expressed in skeletal muscle tissue and 2 other tissues

Family and domain databases

CDDicd00063, FN3, 2 hits
Gene3Di2.60.40.10, 53 hits
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
IPR013106, Ig_V-set
IPR000048, IQ_motif_EF-hand-BS
PfamiView protein in Pfam
PF00041, fn3, 2 hits
PF07679, I-set, 47 hits
SMARTiView protein in SMART
SM00060, FN3, 2 hits
SM00409, IG, 51 hits
SM00408, IGc2, 45 hits
SM00406, IGv, 9 hits
SM00015, IQ, 1 hit
SUPFAMiSSF48726, SSF48726, 51 hits
SSF49265, SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 2 hits
PS50835, IG_LIKE, 43 hits
PS50096, IQ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KFT9_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KFT9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: August 12, 2020
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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