UniProtKB - G1KFP2 (G1KFP2_ANOCA)
Protein
Submitted name:
Uncharacterized protein
Gene
CDK5RAP3
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- cyclin binding Source: Ensembl
- MDM2/MDM4 family protein binding Source: Ensembl
- mitogen-activated protein kinase binding Source: Ensembl
- NF-kappaB binding Source: Ensembl
- ubiquitin-like protein ligase binding Source: Ensembl
GO - Biological processi
- apoptotic nuclear changes Source: Ensembl
- cell population proliferation Source: Ensembl
- definitive erythrocyte differentiation Source: Ensembl
- endoplasmic reticulum unfolded protein response Source: Ensembl
- liver development Source: Ensembl
- mitotic G2 DNA damage checkpoint Source: Ensembl
- negative regulation of cellular protein catabolic process Source: Ensembl
- negative regulation of MAP kinase activity Source: Ensembl
- negative regulation of NF-kappaB transcription factor activity Source: Ensembl
- negative regulation of protein kinase activity by regulation of protein phosphorylation Source: Ensembl
- positive regulation of protein localization to nucleus Source: Ensembl
- positive regulation of protein ubiquitination Source: Ensembl
- positive regulation of signal transduction by p53 class mediator Source: Ensembl
- positive regulation of transcription by RNA polymerase II Source: Ensembl
- protein ufmylation Source: Ensembl
- regulation of cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
- regulation of mitotic cell cycle Source: GO_Central
- regulation of phosphatase activity Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:CDK5RAP3Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Cytoskeleton
- centrosome Source: Ensembl
- microtubule Source: Ensembl
Cytosol
- cytosol Source: Ensembl
Nucleus
- nucleolus Source: Ensembl
Other locations
- protein-containing complex Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000006686, Expressed in heart and 14 other tissues |
Interactioni
GO - Molecular functioni
- cyclin binding Source: Ensembl
- MDM2/MDM4 family protein binding Source: Ensembl
- mitogen-activated protein kinase binding Source: Ensembl
- NF-kappaB binding Source: Ensembl
- ubiquitin-like protein ligase binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000006596 |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 129 – 156 | Sequence analysisAdd BLAST | 28 |
Sequence similaritiesi
Belongs to the CDK5RAP3 family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG2607, Eukaryota |
GeneTreei | ENSGT00390000000713 |
HOGENOMi | CLU_025645_1_0_1 |
InParanoidi | G1KFP2 |
OMAi | PGVRKQM |
OrthoDBi | 619606at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR008491, CDK5RAP3 |
PANTHERi | PTHR14894, PTHR14894, 1 hit |
Pfami | View protein in Pfam PF05600, DUF773, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KFP2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQDYQNLPID IQTSKLLDWL VDRRHCNLKW QGQVRTVREK IAAAIQDMPE
60 70 80 90 100
NEEIKQLLSG SYIHYFHCLR IVEILRGTEA STKNIFGRYS SQRMKDWQEI
110 120 130 140 150
VSLYEKDNTY LVELASLLVR NVNYEIPSLK KQISKCQQLQ QEYSRKEEEC
160 170 180 190 200
QLAATEMRER FYTSCKQYGI MGDNVHRELV ALVKDLPSQL NEIGTGASGL
210 220 230 240 250
SEAIDLYQAC VQFVCDNSTE QVVPLLRHMQ VRGNTTIFEW RRGVKPTSVE
260 270 280 290 300
RPKTEEVKEE TEDEAAIDWG DFGAEPPSAS VTDDYGISVE GTSDDIDWGI
310 320 330 340 350
SLESETQESS AAGIDWGDQT EEAAAQIVVM EASSDAPEGI AKGPDALTIL
360 370 380 390 400
ETPDTRNQFI DELMELEIFL SQRIVETSEE ADILAVSQFQ QAPPILQDQT
410 420 430 440 450
KEKLEAMVAT IQHLLGQLTS LKMQHLFMIL ASPRYVDRVT ELLHQKLKQA
460 470 480 490 500
DLLLLKKDLM IKKRQEALEE QASLEPKLDI LVQKTRELQK LIEADISKRY
510
TGRPVNLMGA SL
Sequence databases
RefSeqi | XP_003222653.1, XM_003222605.3 |
Genome annotation databases
Ensembli | ENSACAT00000006742; ENSACAP00000006596; ENSACAG00000006686 |
GeneIDi | 100559136 |
KEGGi | acs:100559136 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003222653.1, XM_003222605.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000006596 |
Genome annotation databases
Ensembli | ENSACAT00000006742; ENSACAP00000006596; ENSACAG00000006686 |
GeneIDi | 100559136 |
KEGGi | acs:100559136 |
Organism-specific databases
CTDi | 80279 |
Phylogenomic databases
eggNOGi | KOG2607, Eukaryota |
GeneTreei | ENSGT00390000000713 |
HOGENOMi | CLU_025645_1_0_1 |
InParanoidi | G1KFP2 |
OMAi | PGVRKQM |
OrthoDBi | 619606at2759 |
Gene expression databases
Bgeei | ENSACAG00000006686, Expressed in heart and 14 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR008491, CDK5RAP3 |
PANTHERi | PTHR14894, PTHR14894, 1 hit |
Pfami | View protein in Pfam PF05600, DUF773, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KFP2_ANOCA | |
Accessioni | G1KFP2Primary (citable) accession number: G1KFP2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | April 7, 2021 | |
This is version 51 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |