UniProtKB - G1KFI7 (G1KFI7_ANOCA)
Protein
PPM-type phosphatase domain-containing protein
Gene
ILKAP
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Cofactori
Mg2+ARBA annotation
GO - Molecular functioni
- magnesium-dependent protein serine/threonine phosphatase activity Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- protein serine/threonine phosphatase activity Source: GO_Central
Keywordsi
Molecular function | Hydrolase, Protein phosphataseUniRule annotationARBA annotation |
Ligand | MagnesiumARBA annotation, Metal-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: PPM-type phosphatase domain-containing proteinInterPro annotation |
Gene namesi | Name:ILKAPImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Nucleus
- nucleoplasm Source: Ensembl
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000006573, Expressed in adrenal gland and 15 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 108 – 390 | PPM-type phosphataseInterPro annotationAdd BLAST | 283 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 90 | DisorderedSequence analysisAdd BLAST | 90 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 51 – 66 | PolarSequence analysisAdd BLAST | 16 | |
Compositional biasi | 76 – 90 | PolyampholyteSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Belongs to the PP2C family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0698, Eukaryota |
GeneTreei | ENSGT00940000157403 |
HOGENOMi | CLU_013173_1_6_1 |
InParanoidi | G1KFI7 |
OMAi | KKFPKGE |
OrthoDBi | 1044139at2759 |
TreeFami | TF313513 |
Family and domain databases
CDDi | cd00143, PP2Cc, 1 hit |
Gene3Di | 3.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR015655, PP2C IPR000222, PP2C_BS IPR036457, PPM-type_dom_sf IPR001932, PPM-type_phosphatase_dom |
PANTHERi | PTHR13832, PTHR13832, 1 hit |
Pfami | View protein in Pfam PF00481, PP2C, 1 hit |
SMARTi | View protein in SMART SM00331, PP2C_SIG, 1 hit SM00332, PP2Cc, 1 hit |
SUPFAMi | SSF81606, SSF81606, 1 hit |
PROSITEi | View protein in PROSITE PS01032, PPM_1, 1 hit PS51746, PPM_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KFI7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDLFGDFPEQ ASAAPAAIDK EERRGSLLFD DLPPVSGTDL DAGSSLLFDD
60 70 80 90 100
LPPASSGNTV SHPAEQVSLP VSYGRGEKRK STEGEKNGSE ELVEKKVCKD
110 120 130 140 150
FSEILPLKGY VAERKGEREE MQDAHVILND ITEECSPLPS QITRVSYFAV
160 170 180 190 200
FDGHGGVRAS NYAAQNLHQN LIRKFPKGDV PSVEKAIRRC LLDTFKHTDE
210 220 230 240 250
EFLKQASSQK PAWKDGSTAT CVLVIDNTLY IANLGDSRAI LCRYNEENQK
260 270 280 290 300
HTALSLSKEH NPTQYDERMR IQKAGGNVRE GRVLGVLEVS RSIGDGQYKR
310 320 330 340 350
FGVISVPDVK RCQLTHNDRF ILLACDGLFK VFSPEEAVNF IMSCLEDKTI
360 370 380 390
PTRDAKSAAD ARYEAACNRL ANKAVQRGSA DNVTVVVVRI EQ
Sequence databases
RefSeqi | XP_008104645.1, XM_008106438.2 |
Genome annotation databases
Ensembli | ENSACAT00000006598; ENSACAP00000006453; ENSACAG00000006573 |
GeneIDi | 100559844 |
KEGGi | acs:100559844 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_008104645.1, XM_008106438.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000006453 |
Genome annotation databases
Ensembli | ENSACAT00000006598; ENSACAP00000006453; ENSACAG00000006573 |
GeneIDi | 100559844 |
KEGGi | acs:100559844 |
Organism-specific databases
CTDi | 80895 |
Phylogenomic databases
eggNOGi | KOG0698, Eukaryota |
GeneTreei | ENSGT00940000157403 |
HOGENOMi | CLU_013173_1_6_1 |
InParanoidi | G1KFI7 |
OMAi | KKFPKGE |
OrthoDBi | 1044139at2759 |
TreeFami | TF313513 |
Gene expression databases
Bgeei | ENSACAG00000006573, Expressed in adrenal gland and 15 other tissues |
Family and domain databases
CDDi | cd00143, PP2Cc, 1 hit |
Gene3Di | 3.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR015655, PP2C IPR000222, PP2C_BS IPR036457, PPM-type_dom_sf IPR001932, PPM-type_phosphatase_dom |
PANTHERi | PTHR13832, PTHR13832, 1 hit |
Pfami | View protein in Pfam PF00481, PP2C, 1 hit |
SMARTi | View protein in SMART SM00331, PP2C_SIG, 1 hit SM00332, PP2Cc, 1 hit |
SUPFAMi | SSF81606, SSF81606, 1 hit |
PROSITEi | View protein in PROSITE PS01032, PPM_1, 1 hit PS51746, PPM_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KFI7_ANOCA | |
Accessioni | G1KFI7Primary (citable) accession number: G1KFI7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | December 2, 2020 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |