UniProtKB - G1KFH5 (G1KFH5_ANOCA)
Protein
C2H2-type domain-containing protein
Gene
PHF20
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- histone acetyltransferase activity (H4-K16 specific) Source: Ensembl
- histone acetyltransferase activity (H4-K5 specific) Source: Ensembl
- histone acetyltransferase activity (H4-K8 specific) Source: Ensembl
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- histone acetylation Source: GO_Central
- histone H4-K16 acetylation Source: GO_Central
- histone H4-K5 acetylation Source: GO_Central
- histone H4-K8 acetylation Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: C2H2-type domain-containing proteinInterPro annotation |
Gene namesi | Name:PHF20Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosol Source: Ensembl
Nucleus
- MLL1 complex Source: GO_Central
- NSL complex Source: GO_Central
- nuclear membrane Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSACAG00000006565, Expressed in forelimb bud and 14 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 443 – 473 | C2H2-typeInterPro annotationAdd BLAST | 31 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 139 – 364 | DisorderedSequence analysisAdd BLAST | 226 | |
Regioni | 378 – 425 | DisorderedSequence analysisAdd BLAST | 48 | |
Regioni | 471 – 567 | DisorderedSequence analysisAdd BLAST | 97 | |
Regioni | 581 – 609 | DisorderedSequence analysisAdd BLAST | 29 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 153 – 263 | PolyampholyteSequence analysisAdd BLAST | 111 | |
Compositional biasi | 282 – 323 | PolyampholyteSequence analysisAdd BLAST | 42 | |
Compositional biasi | 345 – 359 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 386 – 425 | PolarSequence analysisAdd BLAST | 40 | |
Compositional biasi | 474 – 508 | PolarSequence analysisAdd BLAST | 35 | |
Compositional biasi | 509 – 526 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 527 – 542 | BasicSequence analysisAdd BLAST | 16 | |
Compositional biasi | 549 – 567 | PolarSequence analysisAdd BLAST | 19 | |
Compositional biasi | 586 – 604 | PolyampholyteSequence analysisAdd BLAST | 19 |
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1844, Eukaryota |
GeneTreei | ENSGT00940000156477 |
HOGENOMi | CLU_012707_0_0_1 |
InParanoidi | G1KFH5 |
OrthoDBi | 147824at2759 |
TreeFami | TF106475 |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR041297, Crb2_Tudor IPR022255, DUF3776 IPR037915, PHF20 IPR043449, PHF20-like IPR002999, Tudor IPR019786, Zinc_finger_PHD-type_CS IPR013087, Znf_C2H2_type IPR011011, Znf_FYVE_PHD IPR013083, Znf_RING/FYVE/PHD |
PANTHERi | PTHR15856, PTHR15856, 1 hit PTHR15856:SF27, PTHR15856:SF27, 1 hit |
Pfami | View protein in Pfam PF12618, DUF3776, 1 hit PF18115, Tudor_3, 1 hit |
SMARTi | View protein in SMART SM00333, TUDOR, 2 hits |
SUPFAMi | SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS01359, ZF_PHD_1, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KFH5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRKHPPNRRG ISFEVGAQLE ARDRLKNWYP AHIEEIDYEE GKVLIHFKRW
60 70 80 90 100
NHRYDEWFCW DSPYLRPLEK IQLRKEGLHE EERSSGFRIN DQVLACWSDC
110 120 130 140 150
RFYPAKVTSV NKDGTYTVKF YDGVIQTVKN IHVKAFSKDQ PIVNNPRPKE
160 170 180 190 200
RGNEIPSSPE RWEKFKEQRK ATENHKKDKD EKTLKIERRS KPDKEGKLIV
210 220 230 240 250
PLEKNKVSEK TLPKDGKEDK ENISENDREF SIDSQIEKKP ENDNVKTPPD
260 270 280 290 300
NLKETKRRRG RPPVLPPAEQ GSQTLQPITL ELRRRKITKG GDLPSKRPRL
310 320 330 340 350
QKNMSQDKLK TVPDNEKDSI KKQSSHSTSS NNETLDTEVI IPLPDETEPS
360 370 380 390 400
KEPDSSLKEV TEGPLEVCVE SELKLKEELP PCSEEASQPL VNNSKAEEDS
410 420 430 440 450
IAELSSTPEL QEIPETSIPV ASASKRNDGF SASKAAIEHE PKFRCKFLDC
460 470 480 490 500
SKSFRKAKLL HYHMKYFHGI EKSPEPQQSP TTRNIQTRGS LASEKTNQDI
510 520 530 540 550
SNRRRTTSGC LSTKEKEKNK EKKVRDIAKA KAKKKKKKKK KTKSELSGSE
560 570 580 590 600
ENTEFSQDLS PPRSLISTRC SSTSRSCAHL STQLHGTDSG HRKHKEKINE
610 620 630 640 650
DDTLSESSAD SLLWSDDDCS RDIDVTTNPD EDLEDDDDSG FEIVRCICEV
660 670 680 690 700
EEENDFMIQC EECLCWQHGV CMGLLEENVP EKYTCYICQD PPGKRSSLKY
710 720 730 740 750
WYEKDWLCSG HMHGLAFLGE NYSHQNAKKI VATHQLLGDV QKVIEVLHGL
760 770 780 790 800
QLKMSILQSK EHPDLKLWCQ PWKHLDVEEK SHTMRLIHVE ENCCKEETAS
810 820 830 840 850
YRTFNGTIDK SSAIPSVEES YITSEHCYQK PRAYYPAIEQ RLVVETRNSD
860 870 880 890 900
IDESVNRIRE NGDDTIVERL GWELDREICK LENESKHNYS KIREKVTAEE
910 920 930 940 950
DSDVKLLEKD KEGVVNSQLQ WQLNLLAHVE SLQDEVTHRM DLIEKELDVL
960 970 980 990
ESWLDYTGEL EPPEPLARLP QLKHCIKQLL TDLGKVQQIA LCCST
Sequence databases
RefSeqi | XP_003220526.1, XM_003220478.3 |
Genome annotation databases
Ensembli | ENSACAT00000006556; ENSACAP00000006412; ENSACAG00000006565 |
GeneIDi | 100564388 |
KEGGi | acs:100564388 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003220526.1, XM_003220478.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000006412 |
Genome annotation databases
Ensembli | ENSACAT00000006556; ENSACAP00000006412; ENSACAG00000006565 |
GeneIDi | 100564388 |
KEGGi | acs:100564388 |
Organism-specific databases
CTDi | 51230 |
Phylogenomic databases
eggNOGi | KOG1844, Eukaryota |
GeneTreei | ENSGT00940000156477 |
HOGENOMi | CLU_012707_0_0_1 |
InParanoidi | G1KFH5 |
OrthoDBi | 147824at2759 |
TreeFami | TF106475 |
Gene expression databases
Bgeei | ENSACAG00000006565, Expressed in forelimb bud and 14 other tissues |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR041297, Crb2_Tudor IPR022255, DUF3776 IPR037915, PHF20 IPR043449, PHF20-like IPR002999, Tudor IPR019786, Zinc_finger_PHD-type_CS IPR013087, Znf_C2H2_type IPR011011, Znf_FYVE_PHD IPR013083, Znf_RING/FYVE/PHD |
PANTHERi | PTHR15856, PTHR15856, 1 hit PTHR15856:SF27, PTHR15856:SF27, 1 hit |
Pfami | View protein in Pfam PF12618, DUF3776, 1 hit PF18115, Tudor_3, 1 hit |
SMARTi | View protein in SMART SM00333, TUDOR, 2 hits |
SUPFAMi | SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS01359, ZF_PHD_1, 1 hit PS00028, ZINC_FINGER_C2H2_1, 1 hit PS50157, ZINC_FINGER_C2H2_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KFH5_ANOCA | |
Accessioni | G1KFH5Primary (citable) accession number: G1KFH5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | December 2, 2020 | |
This is version 59 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |