UniProtKB - G1KF39 (G1KF39_ANOCA)
Protein
Non-specific serine/threonine protein kinase
Gene
RPS6KC1
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Catalytic activityi
GO - Molecular functioni
- ATP binding Source: InterPro
- phosphatidylinositol binding Source: InterPro
- protein serine kinase activity Source: UniProtKB-EC
- protein threonine kinase activity Source: UniProtKB-EC
Keywordsi
Molecular function | KinaseARBA annotation, Transferase |
Names & Taxonomyi
Protein namesi | Recommended name: Non-specific serine/threonine protein kinaseARBA annotation (EC:2.7.11.1ARBA annotation) |
Gene namesi | Name:RPS6KC1Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Endosome
- early endosome Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000006181, Expressed in testis and 15 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 8 – 132 | PXInterPro annotationAdd BLAST | 125 | |
Domaini | 696 – 1053 | Protein kinaseInterPro annotationAdd BLAST | 358 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 200 – 220 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 327 – 349 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 447 – 482 | DisorderedSequence analysisAdd BLAST | 36 | |
Regioni | 496 – 526 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 755 – 776 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 789 – 815 | DisorderedSequence analysisAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 328 – 349 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 451 – 466 | PolarSequence analysisAdd BLAST | 16 |
Phylogenomic databases
eggNOGi | KOG0603, Eukaryota KOG2101, Eukaryota |
GeneTreei | ENSGT00940000155656 |
HOGENOMi | CLU_014272_0_0_1 |
InParanoidi | G1KF39 |
OrthoDBi | 255297at2759 |
TreeFami | TF323964 |
Family and domain databases
CDDi | cd07287, PX_RPK118_like, 1 hit cd05576, STKc_RPK118_like, 1 hit |
Gene3Di | 3.30.1520.10, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR007330, MIT IPR036181, MIT_dom_sf IPR000719, Prot_kinase_dom IPR001683, PX_dom IPR036871, PX_dom_sf IPR042132, PX_S6K-delta-1 IPR035053, STK_RPK118-like |
Pfami | View protein in Pfam PF04212, MIT, 1 hit PF00069, Pkinase, 1 hit PF00787, PX, 1 hit |
SMARTi | View protein in SMART SM00745, MIT, 1 hit SM00312, PX, 1 hit SM00220, S_TKc, 1 hit |
SUPFAMi | SSF116846, SSF116846, 1 hit SSF56112, SSF56112, 1 hit SSF64268, SSF64268, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS50195, PX, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KF39-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLSPRDRGGE VARFYTVTEP KRHPRGYTLY KVTARIVSRK NPEDVQEIVV
60 70 80 90 100
WKRYSDFKKL HKELWQIHKH LFRHTELFPP FAKAIVFGRF EESVIEERRQ
110 120 130 140 150
CAEDLLQFSA NIPALYNSKQ LEDFFKDGEV HDGSELIGPA EPLLDSLTDS
160 170 180 190 200
LSICSSEARK DVGVLDDVTL SQSEYGGFSS DSDLISLTVD VDSLAELDDG
210 220 230 240 250
MASNQNSPSR SLGLGFTTDP PVQASAISDH EWSKPDGERE SRGLFTGSLK
260 270 280 290 300
ARLGRRDYLD KAGELIKLAL KKEEEEDYEA AYSFYRKGVD LLLEGVQGES
310 320 330 340 350
SPTRREAVKR KTSEYLMRAE KISSLYCRPS SEDGSTSGPP GSLSSRPSWN
360 370 380 390 400
LRSPAEELKA FRVLGVIDKV LLVMDTRTQQ TFILKGLRKS SEYSRKRKTI
410 420 430 440 450
IPRCVPNMVA LHKYIISEES VFLVLHHAEG GKLWSYISKF LNRSPEESFE
460 470 480 490 500
VPPSRRSSST KIHLHQATPS PEDGRVSMDS RGSIDGSMLK VLPLKTSLSP
510 520 530 540 550
SSHDGSSNHE DGQESSPRWI DSGSSSEEEC TTSYLTLCNE YGQEKVDPGS
560 570 580 590 600
LNEESVMKAG DGIPKEPEGN QAHGVVVSGN LGSAFTSQEV NIFADDADPE
610 620 630 640 650
RASPTRISES LSKSKNSPME LFRIDSKDST TELLGLDFGD KLYSLKSESL
660 670 680 690 700
KQYLFMPDRD KGLDAIENKL GPACQDTISR GSNDSVPVIS FKDVAFDDVS
710 720 730 740 750
SVDEGRPDLL VNLPGIMEPV KEATLDGPAK QMEQNGDVLD SKLLETPDVL
760 770 780 790 800
QLNKSAEPST VPEQKVDHLT GEAREKRNDN QKVIRTFHMA ASDPPGSGDR
810 820 830 840 850
TPFPGPGTGA SSSLDTFNRE DNWLMQAGAK EYKTDINNEA VLLFSDHMDD
860 870 880 890 900
LRKEGTVSSL LQKAESKQSD VGVRGESEIH QIFQDLDERL ALTSRFYLPE
910 920 930 940 950
DCVQRWAAEM VVALDALHRE GIVCRDLNPN NILLNDRGHI QLTYFSRWSE
960 970 980 990 1000
VEDSCDNDAI ERMYCAPEVG VVFEETEACD WWSLGALLFE LITGRTLVEC
1010 1020 1030 1040 1050
HPAGINTHTC LNLPDHISEE ARSLLQQLLQ FNSGERLGAG IAGVDDIKSH
1060
PFFALIDWAE LTK
Sequence databases
RefSeqi | XP_008124046.1, XM_008125839.2 |
Genome annotation databases
Ensembli | ENSACAT00000006193; ENSACAP00000006059; ENSACAG00000006181 |
GeneIDi | 100557472 |
KEGGi | acs:100557472 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_008124046.1, XM_008125839.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000006059 |
Genome annotation databases
Ensembli | ENSACAT00000006193; ENSACAP00000006059; ENSACAG00000006181 |
GeneIDi | 100557472 |
KEGGi | acs:100557472 |
Organism-specific databases
CTDi | 26750 |
Phylogenomic databases
eggNOGi | KOG0603, Eukaryota KOG2101, Eukaryota |
GeneTreei | ENSGT00940000155656 |
HOGENOMi | CLU_014272_0_0_1 |
InParanoidi | G1KF39 |
OrthoDBi | 255297at2759 |
TreeFami | TF323964 |
Gene expression databases
Bgeei | ENSACAG00000006181, Expressed in testis and 15 other tissues |
Family and domain databases
CDDi | cd07287, PX_RPK118_like, 1 hit cd05576, STKc_RPK118_like, 1 hit |
Gene3Di | 3.30.1520.10, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR007330, MIT IPR036181, MIT_dom_sf IPR000719, Prot_kinase_dom IPR001683, PX_dom IPR036871, PX_dom_sf IPR042132, PX_S6K-delta-1 IPR035053, STK_RPK118-like |
Pfami | View protein in Pfam PF04212, MIT, 1 hit PF00069, Pkinase, 1 hit PF00787, PX, 1 hit |
SMARTi | View protein in SMART SM00745, MIT, 1 hit SM00312, PX, 1 hit SM00220, S_TKc, 1 hit |
SUPFAMi | SSF116846, SSF116846, 1 hit SSF56112, SSF56112, 1 hit SSF64268, SSF64268, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS50195, PX, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KF39_ANOCA | |
Accessioni | G1KF39Primary (citable) accession number: G1KF39 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | February 10, 2021 | |
This is version 54 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |