UniProtKB - G1KEZ4 (G1KEZ4_ANOCA)
Protein
Submitted name:
Short stature homeobox
Gene
SHOX
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 136 – 195 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- sequence-specific double-stranded DNA binding Source: Ensembl
GO - Biological processi
- multicellular organism development Source: UniProtKB-UniRule
Keywordsi
Molecular function | Developmental proteinPROSITE-ProRule annotation, DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Short stature homeoboxImported |
Gene namesi | Name:SHOXImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotationARBA annotation
Nucleus
- nucleoplasm Source: Ensembl
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSACAG00000006055, Expressed in dewlap and 7 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 134 – 194 | HomeoboxInterPro annotationAdd BLAST | 61 | |
Domaini | 293 – 306 | OARInterPro annotationAdd BLAST | 14 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 103 | DisorderedSequence analysisAdd BLAST | 103 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 293 – 306 | OARPROSITE-ProRule annotationAdd BLAST | 14 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 87 – 103 | PolyampholyteSequence analysisAdd BLAST | 17 |
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG0490, Eukaryota |
GeneTreei | ENSGT00940000154287 |
HOGENOMi | CLU_047013_5_0_1 |
InParanoidi | G1KEZ4 |
OMAi | PVHLFKE |
TreeFami | TF350757 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR000047, HTH_motif IPR003654, OAR_dom |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF03826, OAR, 1 hit |
PRINTSi | PR00031, HTHREPRESSR |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit PS50803, OAR, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KEZ4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEELTAFVSK SFDQKSKEGA GGGGGGGIGG GGGGGGGSGH KKESITYREV
60 70 80 90 100
LEGGLARSRE LGPAEAGSLQ ELAEGGGGGG CPVHLFKEQP EGDKDSSSKL
110 120 130 140 150
KDFGHAARGA ERIYECKDKR EEVKSEDEDG QTKLKQRRSR TNFTLEQLNE
160 170 180 190 200
LERLFDETHY PDAFMREELS QRLGLSEARV QVWFQNRRAK CRKQENQMHK
210 220 230 240 250
GVILGTASHL DACRVAPYVN MGALRMPFQQ VQAQLQLEGV THAHPHLHPH
260 270 280 290 300
LAAHAPYLMF PPPPFGLPIA SLADSASAAA VVAAAAKSNS KNSSIADLRL
310
KARKHAEALG L
Genome annotation databases
Ensembli | ENSACAT00000006066; ENSACAP00000005933; ENSACAG00000006055 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000005933 |
Genome annotation databases
Ensembli | ENSACAT00000006066; ENSACAP00000005933; ENSACAG00000006055 |
Phylogenomic databases
eggNOGi | KOG0490, Eukaryota |
GeneTreei | ENSGT00940000154287 |
HOGENOMi | CLU_047013_5_0_1 |
InParanoidi | G1KEZ4 |
OMAi | PVHLFKE |
TreeFami | TF350757 |
Gene expression databases
Bgeei | ENSACAG00000006055, Expressed in dewlap and 7 other tissues |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR000047, HTH_motif IPR003654, OAR_dom |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF03826, OAR, 1 hit |
PRINTSi | PR00031, HTHREPRESSR |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit PS50803, OAR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KEZ4_ANOCA | |
Accessioni | G1KEZ4Primary (citable) accession number: G1KEZ4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | October 7, 2020 | |
This is version 70 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |