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UniProtKB - G1KEL1 (G1KEL1_ANOCA)

Entry version 63 (02 Dec 2020)
Sequence version 2 (26 Jun 2013)
Previous versions | rss
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Protein
Submitted name:

Uncharacterized protein

Gene

CEP250

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CEP250Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000005735, Expressed in forelimb bud and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000005625

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2196 – 2243DisorderedSequence analysisAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili84 – 114Sequence analysisAdd BLAST31
Coiled coili122 – 142Sequence analysisAdd BLAST21
Coiled coili280 – 331Sequence analysisAdd BLAST52
Coiled coili401 – 547Sequence analysisAdd BLAST147
Coiled coili569 – 606Sequence analysisAdd BLAST38
Coiled coili618 – 712Sequence analysisAdd BLAST95
Coiled coili723 – 757Sequence analysisAdd BLAST35
Coiled coili772 – 792Sequence analysisAdd BLAST21
Coiled coili807 – 841Sequence analysisAdd BLAST35
Coiled coili851 – 900Sequence analysisAdd BLAST50
Coiled coili923 – 943Sequence analysisAdd BLAST21
Coiled coili962 – 1035Sequence analysisAdd BLAST74
Coiled coili1047 – 1098Sequence analysisAdd BLAST52
Coiled coili1107 – 1130Sequence analysisAdd BLAST24
Coiled coili1145 – 1200Sequence analysisAdd BLAST56
Coiled coili1212 – 1274Sequence analysisAdd BLAST63
Coiled coili1278 – 1383Sequence analysisAdd BLAST106
Coiled coili1387 – 1421Sequence analysisAdd BLAST35
Coiled coili1502 – 1543Sequence analysisAdd BLAST42
Coiled coili1583 – 1617Sequence analysisAdd BLAST35
Coiled coili1632 – 1680Sequence analysisAdd BLAST49
Coiled coili1684 – 1718Sequence analysisAdd BLAST35
Coiled coili1730 – 1788Sequence analysisAdd BLAST59
Coiled coili1803 – 1823Sequence analysisAdd BLAST21
Coiled coili1874 – 1894Sequence analysisAdd BLAST21
Coiled coili1923 – 1957Sequence analysisAdd BLAST35
Coiled coili1962 – 1982Sequence analysisAdd BLAST21
Coiled coili1996 – 2017Sequence analysisAdd BLAST22
Coiled coili2023 – 2096Sequence analysisAdd BLAST74
Coiled coili2115 – 2156Sequence analysisAdd BLAST42
Coiled coili2338 – 2372Sequence analysisAdd BLAST35
Coiled coili2387 – 2414Sequence analysisAdd BLAST28
Coiled coili2422 – 2442Sequence analysisAdd BLAST21
Coiled coili2483 – 2531Sequence analysisAdd BLAST49
Coiled coili2566 – 2586Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QTBY, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161056

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000920_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		G1KEL1

Database of Orthologous Groups

More...OrthoDBi		76868at2759

TreeFam database of animal gene trees

More...TreeFami		TF101138

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KEL1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGDQAAHSM KMESAHLSDD QLVSVHQQMI ESQASYRNKL QNSQEAQHRQ 
        60         70         80         90        100
AILVQKLQGK VLQYRNWCRD LEQRLEASRA SYSLRQDNKK DHSLEKALIQ 
       110        120        130        140        150
LEEEQQRCQN LAGVNILLRD HLDKANEVNG ALREDVSKLT ADWTKARDEL 
       160        170        180        190        200
EYKESEWHKE RKFFESYMRA EHDRIIGIWR QVVTLHRYFL EMKTATDRDL 
       210        220        230        240        250
SELKVEQMRL SGSILISCFQ LSSDTRLLEM SNLESSVLKG SLQQQQQQLY 
       260        270        280        290        300
LKPEKTDMEK EIYQQTQAIM NLRVKGDLAR EDLQSRVIEL TALLEQSQKE 
       310        320        330        340        350
NEEKEKTVKT LRDTLEKSNH LELEYEQEQS RSKTVNEEIL SLRHVIKEIT 
       360        370        380        390        400
EAVLNGNDAT VGKPQVEQSA ELGHSLQLDP GGLDGTLLLV REALMKRSNE 
       410        420        430        440        450
VQHLRQQLLA SQNSITSLEK QQEQQEEHSR FQGQRLEQLE KERETFTSQI 
       460        470        480        490        500
QHQQSTIETY SRDYATLEKS RTELQQHLEV LEQEVWHLRQ NNTELQLKGD 
       510        520        530        540        550
MVNGEKEEQQ QELQRMMRER EYIQEDRNAL EERHSSLKNE LIALREALEK 
       560        570        580        590        600
SHLDGELMKQ EKYELASALE QTEQSLAQLT SAHNKLKAET ADLQGATAKM 
       610        620        630        640        650
SALNEALALD KVGLHQIILK MEQESQMLSD NVDRLEKMKS LSQKQLKQAE 
       660        670        680        690        700
QTNEELCTEK IRLEKLLQKA EELQEGLQDE LKMLKEEQKE TYEKLSQVHH 
       710        720        730        740        750
QHEKSISSLE QAHQESNRLG EMYAKVSKEK EKLMCEKATL EVRLGAVERE 
       760        770        780        790        800
KSALTEQVTE LRSVKDLLES SLFQAQQQVS QLEVAKGQLE MKVHAISQAK 
       810        820        830        840        850
EVIQGEVKCL RIELEAEKSR IEQENEERVQ LLSQAEQKHQ ETLSHRQIVH 
       860        870        880        890        900
KEEMNAVFQE LEGERERHRV ELEEALKRSA KEKEESESTC EQKLLELQKN 
       910        920        930        940        950
ITAIQTRMED ELFKAQNAKQ ELLFEKENER KSLLDELLQT KDKLTSTCQQ 
       960        970        980        990       1000
LEYFRQEIKK HQEEAQVTVQ GLEADLKDAQ HRMKTLEKKH KEEIKSLKEE 
      1010       1020       1030       1040       1050
INILLQQRDA LRSQVQELES QLLIAKDSCQ SISQEAQHHL REGQELSKQK 
      1060       1070       1080       1090       1100
ELEIAHLRKM LEAERKRCEE ISHQSIELQS QKEEMEHRNT ELQAMLQNQW 
      1110       1120       1130       1140       1150
EAEKHLNREL QRKQEEVQRQ CATLQALERE QNLWVEADRQ NSEQHNVLQR 
      1160       1170       1180       1190       1200
QLEEAKFQNK QLQTQKREAD LQNAKLLHQK EELECQNAQL KDALQSQREE 
      1210       1220       1230       1240       1250
AECESTILQS HWEEAQQRYS ELQNWKEKIE DENAELQALL SHQREKMESQ 
      1260       1270       1280       1290       1300
NMELQSKQKE IEHQNIVLQK MKEERSHWEE VEDQNSELKA ALQTMEQKRA 
      1310       1320       1330       1340       1350
SLALSLKETE DRAKKLQESD DAHKDEIAKL STALQLTEQL LAEYRKEMQE 
      1360       1370       1380       1390       1400
LNNEIQSLKQ KTAEKEAALV AQQEQLIQDV EESHTSEQRL KDSVQVLEAE 
      1410       1420       1430       1440       1450
VSTLRQSLRS TESRAEALAS ECQRACSARW EAQSQLSKLH SVLQYMLCNG 
      1460       1470       1480       1490       1500
LEVKVEHGGH GDNNIWNSLS LRTEQDKLIR PALSQSKDFS TELTVERVTE 
      1510       1520       1530       1540       1550
AIQKLRKDLW QSRLERDEVR NNMEKLKQQL IEKEGERDRI SAKAQELQKW 
      1560       1570       1580       1590       1600
FNESQEEKNK AEGKRGSLES ALKTEVIAFK EENVTLRRRL ITLEKTLEST 
      1610       1620       1630       1640       1650
EKQRKDMLDE RDSLQMAKDK LSWELDLLRE SIRASEIQTN AMEKINQSLE 
      1660       1670       1680       1690       1700
QELQTALSAL KTKNEELETQ QKKLATLHQE AEIGKTLQEN VDRLTASLEK 
      1710       1720       1730       1740       1750
KEEEIKFQLQ QIKDLERHRE VQKTTMEHLA ESLEKRTQET ECQKNQIEEV 
      1760       1770       1780       1790       1800
KKQEKMQKAD LERLNLELEK SLQIMQSQQE KIQKLEDLTQ TQSTILKSLT 
      1810       1820       1830       1840       1850
LDLEAKVKET QIKEEKIQIL EKNESSQIGS LLKELGDLKM QLTEKDWELA 
      1860       1870       1880       1890       1900
SQKQLLQECE EQGKKQEKCL HTRLEHMKAI LMDKEREVAS REEQIAGFQQ 
      1910       1920       1930       1940       1950
HEAQRDSHLC DLNEKVKELA FTVAQRDEEL ESQRQQIREM EGEMETELKT 
      1960       1970       1980       1990       2000
LRELTAKTQL SLKERNIELE FQRKHAEEVE RQIKILLGDV QISTAVLNLE 
      2010       2020       2030       2040       2050
DNNAEFQKDQ KEQLKKQTVL NMLEQLRVLL IRKEREIKSL KEQQDEHKEE 
      2060       2070       2080       2090       2100
NEKTVREMQT NLQQALENKE VQLQCLKEEN RQLHQLEEKA AAQTKSVMEN 
      2110       2120       2130       2140       2150
LEFTRTSLHD REKEIQSLKG HIREISRQKE VEQNKAVSLL NDLNKIKQSR 
      2160       2170       2180       2190       2200
TEKENELLRQ VEHIRTYQVK LEATQAELQA CQTRVNELQS VIKQKEEENE 
      2210       2220       2230       2240       2250
RDFKRLRHKH EPVQENDKHP GENEEYLEEK QRKKGEEMDA QNKQEKIKDE 
      2260       2270       2280       2290       2300
MKMLQENIQQ LQHLLKKKDD EVEWQKRKVE ELKERVKSKE KELLISSEHL 
      2310       2320       2330       2340       2350
KEIVSFLNLQ DNEDDNLQSH IQKLHMWKEL EIVRSKALQE KDQWLTRQKE 
      2360       2370       2380       2390       2400
KIQQLEDEKK VKKQELDHVT AILKKTESGE IEWREKAQRL DLSLAQSEEA 
      2410       2420       2430       2440       2450
LRALREEMTI MQNMVSERDR DRHNLQEQLD TAFRTLEEER TATKALVGDV 
      2460       2470       2480       2490       2500
DQFISEKHLP EILGKEGEEA MRKGGKLSWV DERRFLCRRL QLLQQAVARL 
      2510       2520       2530       2540       2550
ENDYRVLEQH NTQLREALKQ VEHERRRLKR SCGDLSLSFG LSQINAGPLK 
      2560       2570       2580       2590       2600
IPSIEKEETQ VLHKELEKLQ KQVFVLQKQL SLQKKQKQDY IDSCARTNHE 
      2610       2620       2630       2640       2650
LSGLHQELSD SLAAVAKEPE ATVLALETQK LDETLNYSLS LASGSCNGFF 
      2660 
AGKHLISSTP KRLQQKDSK
Length:2,669
Mass (Da):313,359
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8D6369FE7C61AA05
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_003220580.1, XM_003220532.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000005748; ENSACAP00000005625; ENSACAG00000005735

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100558279

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		acs:100558279

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_003220580.1, XM_003220532.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000005625

Genome annotation databases

EnsembliENSACAT00000005748; ENSACAP00000005625; ENSACAG00000005735
GeneIDi100558279
KEGGiacs:100558279

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		11190

Phylogenomic databases

eggNOGiENOG502QTBY, Eukaryota
GeneTreeiENSGT00940000161056
HOGENOMiCLU_000920_0_0_1
InParanoidiG1KEL1
OrthoDBi76868at2759
TreeFamiTF101138

Gene expression databases

BgeeiENSACAG00000005735, Expressed in forelimb bud and 14 other tissues

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KEL1_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KEL1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: December 2, 2020
This is version 63 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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