Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Eukaryotic translation initiation factor 6

Gene

EIF6

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factorUniRule annotation
Biological processProtein biosynthesis, Ribosome biogenesisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 6UniRule annotation
Short name:
eIF-6UniRule annotation
Gene namesi
Name:EIF6UniRule annotation
Synonyms:eif6Imported
OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
Taxonomic identifieri28377 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
Proteomesi
  • UP000001646 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotation

Expressioni

Gene expression databases

BgeeiENSACAG00000005487

Interactioni

Subunit structurei

Monomer. Associates with the 60S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi28377.ENSACAP00000005375

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3185 Eukaryota
COG1976 LUCA
GeneTreeiENSGT00390000015972
InParanoidiG1KE62
KOiK03264
OrthoDBiEOG091G0HYF
TreeFamiTF105396

Family and domain databases

CDDicd00527 IF6, 1 hit
HAMAPiMF_00032 eIF_6, 1 hit
InterProiView protein in InterPro
IPR002769 eIF6
PANTHERiPTHR10784 PTHR10784, 1 hit
PfamiView protein in Pfam
PF01912 eIF-6, 1 hit
PIRSFiPIRSF006413 IF-6, 1 hit
SMARTiView protein in SMART
SM00654 eIF6, 1 hit
TIGRFAMsiTIGR00323 eIF-6, 1 hit

Sequencei

Sequence statusi: Complete.

G1KE62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRASFENN NEIGCFAKLT NAYCLVAVGG SEGFYSVFEG ELSDTIPVVH
60 70 80 90 100
ASIAGCRIIG RMCVGNRHGL LVPNNTTDQE LQHIRNCLPD SVRIQRIEER
110 120 130 140 150
LSALGNVTTC NDYVALVHPD IDRETEEILA DVLKVEVFRQ TIAEQVLVGS
160 170 180 190 200
YCTFSNQGGL VHPKTSIEDQ DELSSLLQVP LVAGTVNRGS EVIAAGMVVN
210 220 230 240
DWCAFCGLDT TSTELSVIES VFKLNEAQPS TIATTMRDSL IDSLT
Length:245
Mass (Da):26,583
Last modified:June 26, 2013 - v2
Checksum:i1253224B0685F2A2
GO

Sequence databases

RefSeqiXP_008108145.1, XM_008109938.2

Genome annotation databases

EnsembliENSACAT00000005492; ENSACAP00000005375; ENSACAG00000005487
GeneIDi100562749
KEGGiacs:100562749

Similar proteinsi

Entry informationi

Entry nameiG1KE62_ANOCA
AccessioniPrimary (citable) accession number: G1KE62
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: March 28, 2018
This is version 42 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health