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Entry version 50 (29 Sep 2021)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

DLG associated protein 2

Gene

DLGAP2

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DLG associated protein 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DLGAP2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000005202, Expressed in testis and 2 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000005144

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni165 – 227DisorderedSequence analysisAdd BLAST63
Regioni365 – 386DisorderedSequence analysisAdd BLAST22
Regioni556 – 582DisorderedSequence analysisAdd BLAST27
Regioni891 – 931DisorderedSequence analysisAdd BLAST41

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi165 – 181Polar residuesSequence analysisAdd BLAST17
Compositional biasi192 – 208Basic residuesSequence analysisAdd BLAST17
Compositional biasi909 – 931Basic and acidic residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SAPAP family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3971, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157913

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010880_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1KDV0

Database of Orthologous Groups

More...
OrthoDBi
197925at2759

TreeFam database of animal gene trees

More...
TreeFami
TF321382

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030525, DLGAP2
IPR005026, SAPAP

The PANTHER Classification System

More...
PANTHERi
PTHR12353, PTHR12353, 1 hit
PTHR12353:SF3, PTHR12353:SF3, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03359, GKAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KDV0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKGLSGSRNQ SQLCSAHTCG LASPEDCEHT HDHIHHGQES RQSYLLSPTE
60 70 80 90 100
SCPMDHHRCS PRSSIHSECM MMPMVMGDHM SSSTFPRMHY TSHYDTRDDC
110 120 130 140 150
TMSHANPKVN RIPANLLDQF EKQLPLHRDG FHTLQYQRTS TAAEQRSESP
160 170 180 190 200
GRIRHLVHSV QKLFTKSHSL EGSSKSNVNG TKGDGRGDDH HHGHHSKHGK
210 220 230 240 250
RSKSKERKPE TKHKTGMSSW WSSDDNLDSD STYRTPSVVN RHHVDHISHC
260 270 280 290 300
YPEALQGHFG DLSLKTSKSN NDVKCSACEG LAMAPDGKYM KRSSWSTLTV
310 320 330 340 350
SQAKEAYRKS SLNLDKPLVH QEIKPSLRPC HYLQVPQDEW GGYPAGGKDE
360 370 380 390 400
EIPCRRMRSG SYIKAMGDEE SGDSDTSPKT SPKVAVHPES LLKSIGQRAL
410 420 430 440 450
GDHQNQSYLQ AASDVPGGHS LDPAANYNSP KFRSRNQSYM RAVSTLSQAS
460 470 480 490 500
CISQMSEAEV NGQFESVCES VFSEVEAQAM DALDLPGCFR TRSHSYLRAI
510 520 530 540 550
QAGYSQDDEC IPAMASSNIT STIRSTTAVT YTSYKKTPPP VPPRTTSKPL
560 570 580 590 600
ISITAQSSTE STQDAYHDSR TQRISPWPQD SRGMYNSTDS LDSNKAMNLA
610 620 630 640 650
LETAAAQRHM SENQSTSVRT SDKAILVTKA EEFRKSRRSS IGIQVETATD
660 670 680 690 700
SDTESKGLRE YHSVGVQVEN DKRHGRFKRS NSVTAAVQAD LELEGFPGHI
710 720 730 740 750
TMEDKGLQFG GSFQRHSEPS TPTQYGAVRT VRTQGLFSYR EDYRTQVDTS
760 770 780 790 800
NLPPPEPWLE PAIETVETGR MSPCRRDGSW FMKLLHTETK RMEGWCKEME
810 820 830 840 850
REAEENDLSE EILGKIRSAV GSAQLLMSQK FQQFYWLCQQ NLDPSAMPRP
860 870 880 890 900
TSQDLAGFWD LLQLSIEDVS IKFDELHQLK LNEWKIIESP ERKEERKVPP
910 920 930 940 950
PVPKKPPKGK FPITREKSLD LPDRQRQEAR RRLMAAKRAA SFRQNSATER
960
ADSIEIYIPE AQTRL
Length:965
Mass (Da):108,470
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8EF71443C8F193CC
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_008116589.1, XM_008118382.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000005261; ENSACAP00000005144; ENSACAG00000005202

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100564562

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
acs:100564562

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_008116589.1, XM_008118382.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000005144

Genome annotation databases

EnsembliENSACAT00000005261; ENSACAP00000005144; ENSACAG00000005202
GeneIDi100564562
KEGGiacs:100564562

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9228

Phylogenomic databases

eggNOGiKOG3971, Eukaryota
GeneTreeiENSGT00940000157913
HOGENOMiCLU_010880_0_0_1
InParanoidiG1KDV0
OrthoDBi197925at2759
TreeFamiTF321382

Gene expression databases

BgeeiENSACAG00000005202, Expressed in testis and 2 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR030525, DLGAP2
IPR005026, SAPAP
PANTHERiPTHR12353, PTHR12353, 1 hit
PTHR12353:SF3, PTHR12353:SF3, 1 hit
PfamiView protein in Pfam
PF03359, GKAP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KDV0_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KDV0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: September 29, 2021
This is version 50 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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