UniProtKB - G1KDD4 (G1KDD4_ANOCA)
Protein
Terpene cyclase/mutase family member
Gene
LSS
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- beta-amyrin synthase activity Source: InterPro
- lanosterol synthase activity Source: GO_Central
GO - Biological processi
- cholesterol biosynthetic process Source: GO_Central
- regulation of protein stability Source: Ensembl
- triterpenoid biosynthetic process Source: InterPro
Keywordsi
Molecular function | IsomeraseUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Terpene cyclase/mutase family memberUniRule annotation (EC:5.4.99.-UniRule annotation) |
Gene namesi | Name:LSSImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: Ensembl
Other locations
- lipid droplet Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000004914, Expressed in hindlimb bud and 14 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 107 – 372 | SQHop_cyclase_NInterPro annotationAdd BLAST | 266 | |
Domaini | 406 – 741 | SQHop_cyclase_CInterPro annotationAdd BLAST | 336 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 39 | DisorderedSequence analysisAdd BLAST | 39 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 22 – 36 | PolyampholyteSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
eggNOGi | KOG0497, Eukaryota |
GeneTreei | ENSGT00390000011570 |
HOGENOMi | CLU_009074_2_1_1 |
InParanoidi | G1KDD4 |
OrthoDBi | 365003at2759 |
TreeFami | TF300406 |
Family and domain databases
CDDi | cd02892, SQCY_1, 1 hit |
InterProi | View protein in InterPro IPR032696, SQ_cyclase_C IPR032697, SQ_cyclase_N IPR018333, Squalene_cyclase IPR002365, Terpene_synthase_CS IPR008930, Terpenoid_cyclase/PrenylTrfase |
Pfami | View protein in Pfam PF13243, SQHop_cyclase_C, 1 hit PF13249, SQHop_cyclase_N, 1 hit |
SUPFAMi | SSF48239, SSF48239, 2 hits |
TIGRFAMsi | TIGR01787, squalene_cyclas, 1 hit |
PROSITEi | View protein in PROSITE PS01074, TERPENE_SYNTHASES, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KDD4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPSITPAAL GVSSDLPESS RMDGTCLRRR RGGPYKTEPA TDLTRWRLSN
60 70 80 90 100
EEGRQCWRYV ADGENFDREQ TGLEAHSLGL DTSKFFPVLS KANTAQEAAI
110 120 130 140 150
NGVQFYSGLQ AEDGHWAGDY GGPLFLLPGL LITCHAAKIP LPEESKKEMV
160 170 180 190 200
RYLRSVQLPD GGWGLHIEDK STVFSIALNY TAMRILGVSP DDPDLVRARN
210 220 230 240 250
NLHSKGGAVK IPSWGKFWLA VLNVYSWEGM NTLFPEMWLF PSWMPAHPST
260 270 280 290 300
LWCHCRQVYL PMAYCYGRRL TAEEDELILS LRQELYVQDY STIDWPAQRN
310 320 330 340 350
NVASGDIYTP HSWLLTVAYA ILNTYERFHS TSLRQHALEV LYDHIRADDR
360 370 380 390 400
FTKAISIGPI SKTINMLVSW YVEGDKSPAF QEHVSRIPDY LWLGLDGLKM
410 420 430 440 450
QGTNGSQLWD TAFAVQAFLE AGAHKKPEFN SCLLHAHEFF RISQIPDNPP
460 470 480 490 500
DYEKYYRQMN KGGFPFSTRD CGWIVADCTA EGMKSVMLMQ EKCPFIKDHI
510 520 530 540 550
PPSRLFDAVN VLLNMQNADG GFSTYETMRG GWLLELLNPS EVFGNIMVDY
560 570 580 590 600
TYVECTSAVM QALKHFHERF PEHRALEIRE VLQKGLQYCR RLQRADGSWE
610 620 630 640 650
GSWGVCFTYG MWFALEAFAC MQHTYRDGVA CKEISRACEF LISKQMEDGG
660 670 680 690 700
WGEDFESCEQ RTYVQSATSQ IHNTCWALLG LMAVRYPDVK VLEKGIKLLI
710 720 730 740 750
DKQLPNGDWP QENISGVFNK SCAISYTSYR NVFPIWTLGR FSHLHCTSPL
760 770 780
AGKLSSEALK NGEGSLARGK ANEHSFTFAS S
Sequence databases
RefSeqi | XP_003215262.1, XM_003215214.3 |
Genome annotation databases
Ensembli | ENSACAT00000004954; ENSACAP00000004844; ENSACAG00000004914 |
GeneIDi | 100558321 |
KEGGi | acs:100558321 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003215262.1, XM_003215214.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000004844 |
Genome annotation databases
Ensembli | ENSACAT00000004954; ENSACAP00000004844; ENSACAG00000004914 |
GeneIDi | 100558321 |
KEGGi | acs:100558321 |
Organism-specific databases
CTDi | 4047 |
Phylogenomic databases
eggNOGi | KOG0497, Eukaryota |
GeneTreei | ENSGT00390000011570 |
HOGENOMi | CLU_009074_2_1_1 |
InParanoidi | G1KDD4 |
OrthoDBi | 365003at2759 |
TreeFami | TF300406 |
Gene expression databases
Bgeei | ENSACAG00000004914, Expressed in hindlimb bud and 14 other tissues |
Family and domain databases
CDDi | cd02892, SQCY_1, 1 hit |
InterProi | View protein in InterPro IPR032696, SQ_cyclase_C IPR032697, SQ_cyclase_N IPR018333, Squalene_cyclase IPR002365, Terpene_synthase_CS IPR008930, Terpenoid_cyclase/PrenylTrfase |
Pfami | View protein in Pfam PF13243, SQHop_cyclase_C, 1 hit PF13249, SQHop_cyclase_N, 1 hit |
SUPFAMi | SSF48239, SSF48239, 2 hits |
TIGRFAMsi | TIGR01787, squalene_cyclas, 1 hit |
PROSITEi | View protein in PROSITE PS01074, TERPENE_SYNTHASES, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KDD4_ANOCA | |
Accessioni | G1KDD4Primary (citable) accession number: G1KDD4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | December 2, 2020 | |
This is version 59 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |