UniProtKB - G1KCU2 (G1KCU2_ANOCA)
Protein
DUF1619 domain-containing protein
Gene
TCTN3
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Biological processi
- cilium assembly Source: GO_Central
- positive regulation of apoptotic process Source: Ensembl
- smoothened signaling pathway Source: GO_Central
Keywordsi
Biological process | Cilium biogenesis/degradationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: DUF1619 domain-containing proteinInterPro annotation |
Gene namesi | Name:TCTN3Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Nucleus
- nucleus Source: Ensembl
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_5003412715 | 22 – 613 | DUF1619 domain-containing proteinSequence analysisAdd BLAST | 592 |
Keywords - PTMi
GlycoproteinARBA annotationExpressioni
Gene expression databases
Bgeei | ENSACAG00000004453, Expressed in forelimb bud and 14 other tissues |
Interactioni
Subunit structurei
Part of the tectonic-like complex (also named B9 complex).
ARBA annotationProtein-protein interaction databases
STRINGi | 28377.ENSACAP00000004338 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 97 – 397 | DUF1619InterPro annotationAdd BLAST | 301 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 22 – 93 | DisorderedSequence analysisAdd BLAST | 72 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 22 – 62 | PolarSequence analysisAdd BLAST | 41 |
Sequence similaritiesi
Belongs to the tectonic family.ARBA annotation
Keywords - Domaini
SignalSequence analysisARBA annotationPhylogenomic databases
eggNOGi | ENOG502RKDI, Eukaryota |
GeneTreei | ENSGT00570000079101 |
HOGENOMi | CLU_016974_1_0_1 |
InParanoidi | G1KCU2 |
OrthoDBi | 446525at2759 |
TreeFami | TF329169 |
Family and domain databases
InterProi | View protein in InterPro IPR011677, DUF1619 IPR040354, Tectonic |
PANTHERi | PTHR14611, PTHR14611, 1 hit |
Pfami | View protein in Pfam PF07773, DUF1619, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KCU2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MELTLQLLLL LFLSVSGLSK AQTEEENVTL NAEEVSSTSK PEESSSTLKA
60 70 80 90 100
EDINSTLGAE NSTLKAEEPP TEAARPSETP GVQREEESPE SPGDSLCPCD
110 120 130 140 150
LHPGFCDLNC CCDSNCGLQC TLGSSNCPFS FCLPGSTRAV SQICLDKSLI
160 170 180 190 200
FRNSTPYHTQ ILPSPDGCTL LFCVQLNDSK LNYLQKPQLV TKENFPALSA
210 220 230 240 250
EYGGSSFILP EQVQSSPASF YQVGDPIQTY FASSSMLSVL KQPVGIGVSQ
260 270 280 290 300
LCLDENSAGF LESKSTNCLR IFTDLLKSCT TDPVLDAASY YRNFTVLKVP
310 320 330 340 350
VNYTVFQPVQ VNITALSEPP SPSLIDGICH NVVTEVSYEV QFNGILGIQE
360 370 380 390 400
VSVQFKVANI SGNPRATVQQ HFFLHFWNRS PSTRQRSGNP GYITGAPLIA
410 420 430 440 450
LYNGTEQYIT ILKNQADGQC SATERYNVLF GENVRTGCQL SVPFTLEEET
460 470 480 490 500
CSNLQEMLYE AFQGGHGPRS LAIIGNANPE HLGEWNSIIT KRCNMQNGHC
510 520 530 540 550
MLPVSLEIQV IWAQVGLLSN PQAQVLGARY YYHCKPLTSL DLSMNMISLK
560 570 580 590 600
TAATFTDVTK WPEPARGQPR ITWKLPFDFF FPFKVAFSGA VSSSGNLAGS
610
LLTSLMSYGL HVS
Sequence databases
RefSeqi | XP_008104703.1, XM_008106496.2 |
Genome annotation databases
Ensembli | ENSACAT00000004438; ENSACAP00000004338; ENSACAG00000004453 |
GeneIDi | 103278229 |
KEGGi | acs:103278229 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_008104703.1, XM_008106496.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000004338 |
Genome annotation databases
Ensembli | ENSACAT00000004438; ENSACAP00000004338; ENSACAG00000004453 |
GeneIDi | 103278229 |
KEGGi | acs:103278229 |
Organism-specific databases
CTDi | 26123 |
Phylogenomic databases
eggNOGi | ENOG502RKDI, Eukaryota |
GeneTreei | ENSGT00570000079101 |
HOGENOMi | CLU_016974_1_0_1 |
InParanoidi | G1KCU2 |
OrthoDBi | 446525at2759 |
TreeFami | TF329169 |
Gene expression databases
Bgeei | ENSACAG00000004453, Expressed in forelimb bud and 14 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR011677, DUF1619 IPR040354, Tectonic |
PANTHERi | PTHR14611, PTHR14611, 1 hit |
Pfami | View protein in Pfam PF07773, DUF1619, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KCU2_ANOCA | |
Accessioni | G1KCU2Primary (citable) accession number: G1KCU2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | December 2, 2020 | |
This is version 48 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |