Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - G1KCS3 (G1KCS3_ANOCA)

Entry version 65 (07 Oct 2020)
Sequence version 2 (26 Jun 2013)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

LOC100555140

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphataseARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LOC100555140Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1087 – 1108HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000004413, Expressed in embryonic post-anal tail and 10 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 127Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini128 – 223Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini307 – 397Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini474 – 565Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini566 – 653Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini654 – 751Fibronectin type-IIIInterPro annotationAdd BLAST98
Domaini836 – 933Fibronectin type-IIIInterPro annotationAdd BLAST98
Domaini1157 – 1416Tyrosine-protein phosphataseInterPro annotationAdd BLAST260
Domaini1466 – 1709Tyrosine-protein phosphataseInterPro annotationAdd BLAST244
Domaini1626 – 1700TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75

Keywords - Domaini

RepeatARBA annotation, SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0791, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000164079

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002844_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		G1KCS3

TreeFam database of animal gene trees

More...TreeFami		TF351926

Family and domain databases

Conserved Domains Database

More...CDDi		cd00063, FN3, 6 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 8 hits
3.90.190.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
IPR029021, Prot-tyrosine_phosphatase-like
IPR000242, PTPase_domain
IPR041201, PTPRJ_TM
IPR003595, Tyr_Pase_cat
IPR000387, TYR_PHOSPHATASE_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00041, fn3, 5 hits
PF18861, PTP_tm, 1 hit
PF00102, Y_phosphatase, 2 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00700, PRTYPHPHTASE

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00060, FN3, 10 hits
SM00194, PTPc, 2 hits
SM00404, PTPc_motif, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49265, SSF49265, 10 hits
SSF52799, SSF52799, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50853, FN3, 7 hits
PS50056, TYR_PHOSPHATASE_2, 1 hit
PS50055, TYR_PHOSPHATASE_PTP, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KCS3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVWAPLPIHP QILVEDDRCN QTNWQRNPEG VPDKKSHLLN VSVSNQGRSN 
        60         70         80         90        100
SLFLTWEKLP RGVQNVSLAL YKFDTNTVLQ NGSAGLNATG FLFEGLLPGT 
       110        120        130        140        150
QYDIEVTVLL ICTQNSSRRV TGRTVPGPVR NVVLSHNSPS MLLASWSEAT 
       160        170        180        190        200
GGKDAYQLVL YHIKSQAPVK NVTIPRNATT YRFEKLLNGS EYALQITTLA 
       210        220        230        240        250
GSYKASTIAR HWTAPVVPET LAFQNSGSSS NLSASWSNAG GAEWFHFTLQ 
       260        270        280        290        300
NLHTVTEITT VSLKRGLTNY TFQHLKPGNP YRLEVSATAG PYRVEGPKVT 
       310        320        330        340        350
AYTYPLAPSG ITLVSSRWPS SLLASWEIPQ GDRDQFFLRF YSQERPLLQR 
       360        370        380        390        400
NVTIGPDKQN FTFEGLLPGT QYFLEVSALA GPYRASSQVV SAWTCEYSKL 
       410        420        430        440        450
YLKGVKASGR GREYWVQLYS EESLSFIQNV SVPHGTTQVT LNNLVPGTRY 
       460        470        480        490        500
RVEIVSRAGP HYISSQTAIG YTVPLMPLSL MVTSPISSVL SVQWKAPAGQ 
       510        520        530        540        550
RDKYMVSVSE EGATDTKWHM AIEKANTNTT ITGLAPGTCY FIAVWSLAGP 
       560        570        580        590        600
YSSASRNDTA CTPPAPPVNL TLKNLANASV LYTAWAKPPG GRDHYRMILY 
       610        620        630        640        650
SLLPPGMERV RDVGPDTQDF LWTGLPAGSQ FAVQVTAVKG QAEASSTIAV 
       660        670        680        690        700
AWTSPLPVTF VKTWNEKRPG RLSVSWVPTS GRLDSYELNL YPSEPIATAL 
       710        720        730        740        750
HTSLGKDATN FTFSGLLPGT KYLYEIISRA GPTRSSSGNF SAWTNPLVPR 
       760        770        780        790        800
KLAIKSDKRN PALLVTWAKP LSKPERCQLQ LWLSGNKTVL QRHTLVKWEI 
       810        820        830        840        850
QHVFQGLVPG RNYSVSLSCT AGPYENSSEM MAMPIEPSQV KELQCLPDAT 
       860        870        880        890        900
SMFLNWTISE GDIEAYELTV RKFSRGGLQK SKRLLAVSRA DTILTELTSN 
       910        920        930        940        950
TAYQISVSAV GKNGMKSPMV ALGCNTSVEV LPPPVQVDIP QFDDSSRVII 
       960        970        980        990       1000
SPDMFSEDNG LIEYYGVVVT TNESLLRPTQ DIISRTWYDH YYGHEDSYLA 
      1010       1020       1030       1040       1050
LLLPNPFHLN ESTSPKSWPV TVGAEECSQS RETCNGKLKT DAQYSIRFSI 
      1060       1070       1080       1090       1100
AAFTRYSQRT PRVSFTSFSA ADASTASAAS VNISAPLVSG IIVGFLATVT 
      1110       1120       1130       1140       1150
AIAGWICWRH LRARRMEKGN MPQEMITYSL RNTHRPIPLQ SFRQYYETRA 
      1160       1170       1180       1190       1200
ANSNNGFFQD FEELKEVGKD QPKTEAELPA NTSKNRYPHV LPYDYSRVKL 
      1210       1220       1230       1240       1250
SLVDEEPHSD YINANFVPGY NSPQEFIATQ GPLKKTLDDF WRLVWEQHIC 
      1260       1270       1280       1290       1300
TIVMLTVGME NGRVLCEYYW PSDSSPFCSG QIRIHLLAQN FADEWTTREF 
      1310       1320       1330       1340       1350
RIQHEGLNME RRVIHLHYTA WSNHGVPEST TSLNAFVELV RAHMQSASET 
      1360       1370       1380       1390       1400
GPTLVHAGPA PGPADHFAAV SPFILLNYLS LILTGLTTLQ LFTLKPPVSW 
      1410       1420       1430       1440       1450
LTHGQYIFLH SCILEKISEE PLLDQSGLEL SHPIPLKNFV QHHAKNCSKA 
      1460       1470       1480       1490       1500
NAGFLREYEV LLEAAKEEVN SVLPFSGSQP IGLESDDRSK VKFSPLDRDP 
      1510       1520       1530       1540       1550
FSDLSHVWFI PGCNSVKDYI AIEGPDKLAL EEFWGLIWEY GVHTIITLLP 
      1560       1570       1580       1590       1600
GQMNCPAPDN SCWPSESDPV CTERLTIQQG PKKVVSGWPC IQLRLKYEKK 
      1610       1620       1630       1640       1650
AKERLLQRFQ FPLAEGEELP DPEILVGFLT VIRQLVPYRK RTSPVVLHCS 
      1660       1670       1680       1690       1700
MGGLGQMGML IALDTLLQQL KEEKSVDVYG VVLRLVRSCC LMTPTLDRYI 
      1710 
YLYDCIRDTI TQKQPNSRI
Length:1,719
Mass (Da):191,514
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4B5E77D2608620D5
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000004372; ENSACAP00000004272; ENSACAG00000004413

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSACAT00000004372; ENSACAP00000004272; ENSACAG00000004413

Phylogenomic databases

eggNOGiKOG0791, Eukaryota
GeneTreeiENSGT00940000164079
HOGENOMiCLU_002844_0_0_1
InParanoidiG1KCS3
TreeFamiTF351926

Gene expression databases

BgeeiENSACAG00000004413, Expressed in embryonic post-anal tail and 10 other tissues

Family and domain databases

CDDicd00063, FN3, 6 hits
Gene3Di2.60.40.10, 8 hits
3.90.190.10, 2 hits
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
IPR029021, Prot-tyrosine_phosphatase-like
IPR000242, PTPase_domain
IPR041201, PTPRJ_TM
IPR003595, Tyr_Pase_cat
IPR000387, TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00041, fn3, 5 hits
PF18861, PTP_tm, 1 hit
PF00102, Y_phosphatase, 2 hits
PRINTSiPR00700, PRTYPHPHTASE
SMARTiView protein in SMART
SM00060, FN3, 10 hits
SM00194, PTPc, 2 hits
SM00404, PTPc_motif, 2 hits
SUPFAMiSSF49265, SSF49265, 10 hits
SSF52799, SSF52799, 2 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 7 hits
PS50056, TYR_PHOSPHATASE_2, 1 hit
PS50055, TYR_PHOSPHATASE_PTP, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KCS3_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KCS3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: October 7, 2020
This is version 65 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again