UniProtKB - G1KBU5 (G1KBU5_ANOCA)
Protein
Cys_knot domain-containing protein
Gene
TSHB
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- hormone activity Source: UniProtKB-KW
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: GO_Central
- hormone-mediated signaling pathway Source: GO_Central
Keywordsi
Molecular function | HormoneUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Cys_knot domain-containing proteinInterPro annotation |
Gene namesi | Name:TSHBImported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Extracellular region or secreted
- Secreted UniRule annotationARBA annotation
Extracellular region or secreted
- extracellular space Source: GO_Central
Other locations
- cytoplasm Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | Sequence analysisAdd BLAST | 22 | |
ChainiPRO_5003412701 | 23 – 140 | Cys_knot domain-containing proteinSequence analysisAdd BLAST | 118 |
Expressioni
Gene expression databases
Bgeei | ENSACAG00000003405, Expressed in embryo and 11 other tissues |
Interactioni
GO - Molecular functioni
- hormone activity Source: UniProtKB-KW
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000003285 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 26 – 131 | Cys_knotInterPro annotationAdd BLAST | 106 |
Sequence similaritiesi
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | ENOG502S2JW, Eukaryota |
GeneTreei | ENSGT00940000158152 |
HOGENOMi | CLU_126319_0_2_1 |
InParanoidi | G1KBU5 |
TreeFami | TF332940 |
Family and domain databases
CDDi | cd00069, GHB_like, 1 hit |
Gene3Di | 2.10.90.10, 1 hit |
InterProi | View protein in InterPro IPR029034, Cystine-knot_cytokine IPR006208, Glyco_hormone_CN IPR001545, Gonadotropin_bsu IPR018245, Gonadotropin_bsu_CS |
PANTHERi | PTHR11515, PTHR11515, 1 hit |
Pfami | View protein in Pfam PF00007, Cys_knot, 1 hit |
SMARTi | View protein in SMART SM00068, GHB, 1 hit |
SUPFAMi | SSF57501, SSF57501, 1 hit |
PROSITEi | View protein in PROSITE PS00689, GLYCO_HORMONE_BETA_2, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KBU5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGENMNPALL ISLPFFLALT LGQSMSFCIP VDYVIHVEKR ECAYCLAINT
60 70 80 90 100
TICEGFCMTW DSNGKKLLPR SALSQDVCTY KDMVYRTVMI PGCQHHAVSY
110 120 130 140
YTYPVALSCK CGKCNTDYTD CIQEAGHTEY CTVSQQLYNP
Genome annotation databases
Ensembli | ENSACAT00000003368; ENSACAP00000003285; ENSACAG00000003405 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000003285 |
Genome annotation databases
Ensembli | ENSACAT00000003368; ENSACAP00000003285; ENSACAG00000003405 |
Phylogenomic databases
eggNOGi | ENOG502S2JW, Eukaryota |
GeneTreei | ENSGT00940000158152 |
HOGENOMi | CLU_126319_0_2_1 |
InParanoidi | G1KBU5 |
TreeFami | TF332940 |
Gene expression databases
Bgeei | ENSACAG00000003405, Expressed in embryo and 11 other tissues |
Family and domain databases
CDDi | cd00069, GHB_like, 1 hit |
Gene3Di | 2.10.90.10, 1 hit |
InterProi | View protein in InterPro IPR029034, Cystine-knot_cytokine IPR006208, Glyco_hormone_CN IPR001545, Gonadotropin_bsu IPR018245, Gonadotropin_bsu_CS |
PANTHERi | PTHR11515, PTHR11515, 1 hit |
Pfami | View protein in Pfam PF00007, Cys_knot, 1 hit |
SMARTi | View protein in SMART SM00068, GHB, 1 hit |
SUPFAMi | SSF57501, SSF57501, 1 hit |
PROSITEi | View protein in PROSITE PS00689, GLYCO_HORMONE_BETA_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KBU5_ANOCA | |
Accessioni | G1KBU5Primary (citable) accession number: G1KBU5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | August 12, 2020 | |
This is version 50 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |