UniProtKB - G1KBN3 (G1KBN3_ANOCA)
Protein
Submitted name:
Uncharacterized protein
Gene
PACSIN3
Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Functioni
GO - Molecular functioni
- calcium channel inhibitor activity Source: Ensembl
- cytoskeletal protein binding Source: GO_Central
- identical protein binding Source: Ensembl
- phospholipid binding Source: GO_Central
GO - Biological processi
- cytoskeleton organization Source: GO_Central
- negative regulation of calcium ion transport Source: Ensembl
- negative regulation of endocytosis Source: Ensembl
- plasma membrane tubulation Source: GO_Central
- positive regulation of membrane protein ectodomain proteolysis Source: Ensembl
- regulation of endocytosis Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:PACSIN3Imported |
Organismi | Anolis carolinensis (Green anole) (American chameleon)Imported |
Taxonomic identifieri | 28377 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis |
Proteomesi |
|
Subcellular locationi
Cytoskeleton
- cytoskeleton Source: GO_Central
Cytosol
- cytosol Source: Ensembl
Endosome
- endosome Source: GO_Central
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- cytoplasm Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSACAG00000003162, Expressed in skeletal muscle tissue and 14 other tissues |
Interactioni
GO - Molecular functioni
- cytoskeletal protein binding Source: GO_Central
- identical protein binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000003114 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 280 | F-BARInterPro annotationAdd BLAST | 271 | |
Domaini | 396 – 457 | SH3InterPro annotationAdd BLAST | 62 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 158 – 185 | DisorderedSequence analysisAdd BLAST | 28 | |
Regioni | 307 – 348 | DisorderedSequence analysisAdd BLAST | 42 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 185 – 212 | Sequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 158 – 172 | PolyampholyteSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Coiled coilPROSITE-ProRule annotationARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG2856, Eukaryota |
GeneTreei | ENSGT00950000182973 |
HOGENOMi | CLU_030752_0_0_1 |
InParanoidi | G1KBN3 |
OrthoDBi | 727724at2759 |
TreeFami | TF313677 |
Family and domain databases
Gene3Di | 1.20.1270.60, 1 hit |
InterProi | View protein in InterPro IPR027267, AH/BAR_dom_sf IPR031160, F_BAR IPR001060, FCH_dom IPR028523, PACSIN3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR23065:SF18, PTHR23065:SF18, 1 hit |
Pfami | View protein in Pfam PF00611, FCH, 1 hit PF14604, SH3_9, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00055, FCH, 1 hit SM00326, SH3, 1 hit |
SUPFAMi | SSF103657, SSF103657, 1 hit SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51741, F_BAR, 1 hit PS50002, SH3, 1 hit |
i Sequence
Sequence statusi: Complete.
G1KBN3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAEEDAGGE VPSGSFWEPG NYKKTVKRVD DGNRLCNDLV SCFQERAKIE
60 70 80 90 100
KNYAQQLTDW SRKWRSAVEK GPQYGTLEKA WHAFLTAADK LSEIHLEVRN
110 120 130 140 150
HLAGVDSDKV KAWQKEAFHK QMMGGFKETK EAEDGFRKAQ KPWVKKLKDV
160 170 180 190 200
EMAKKNYHTA RKEEKTAQTR ENHAKADSSL SQEQARKLQD RVEKCTQEAE
210 220 230 240 250
KCKDLYEKML EELNRYNPRY MEDMEQVFES CQDAECKRLC FFKEMLLDLH
260 270 280 290 300
NHLNLSTNES FHALYRDLHQ GIMSADDQED LKWWRNTYGP GMAMNWPQFE
310 320 330 340 350
EWSLETQRPI SKKEKSGKSA EDVTLTSIVP AGDDAKQSPP PTKQRFSYQE
360 370 380 390 400
EQNNHLYDTL RASACMNGGK EEIAEWSDED TPKKCLDVNG HEDIKVPGVR
410 420 430 440 450
VRALYDYTGQ EADELSFKAG EELMKISEED EQGWCKGRLL TGQVGLYPAN
YVEKVVS
Sequence databases
RefSeqi | XP_003214646.1, XM_003214598.3 XP_008103180.1, XM_008104973.2 |
Genome annotation databases
Ensembli | ENSACAT00000003193; ENSACAP00000003114; ENSACAG00000003162 |
GeneIDi | 100567497 |
KEGGi | acs:100567497 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003214646.1, XM_003214598.3 XP_008103180.1, XM_008104973.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 28377.ENSACAP00000003114 |
Genome annotation databases
Ensembli | ENSACAT00000003193; ENSACAP00000003114; ENSACAG00000003162 |
GeneIDi | 100567497 |
KEGGi | acs:100567497 |
Organism-specific databases
CTDi | 29763 |
Phylogenomic databases
eggNOGi | KOG2856, Eukaryota |
GeneTreei | ENSGT00950000182973 |
HOGENOMi | CLU_030752_0_0_1 |
InParanoidi | G1KBN3 |
OrthoDBi | 727724at2759 |
TreeFami | TF313677 |
Gene expression databases
Bgeei | ENSACAG00000003162, Expressed in skeletal muscle tissue and 14 other tissues |
Family and domain databases
Gene3Di | 1.20.1270.60, 1 hit |
InterProi | View protein in InterPro IPR027267, AH/BAR_dom_sf IPR031160, F_BAR IPR001060, FCH_dom IPR028523, PACSIN3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR23065:SF18, PTHR23065:SF18, 1 hit |
Pfami | View protein in Pfam PF00611, FCH, 1 hit PF14604, SH3_9, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00055, FCH, 1 hit SM00326, SH3, 1 hit |
SUPFAMi | SSF103657, SSF103657, 1 hit SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51741, F_BAR, 1 hit PS50002, SH3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | G1KBN3_ANOCA | |
Accessioni | G1KBN3Primary (citable) accession number: G1KBN3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | June 26, 2013 | |
Last modified: | December 2, 2020 | |
This is version 62 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |