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Entry version 64 (02 Jun 2021)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

TUBGCP6

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TUBGCP6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaIguaniaDactyloidaeAnolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation, MicrotubuleARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSACAG00000002182, Expressed in female gonad and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
28377.ENSACAP00000002107

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini367 – 696GCP_N_terminalInterPro annotationAdd BLAST330
Domaini1430 – 1731GCP_C_terminalInterPro annotationAdd BLAST302

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni266 – 291DisorderedSequence analysisAdd BLAST26
Regioni1237 – 1266DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili719 – 739Sequence analysisAdd BLAST21
Coiled coili744 – 771Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi269 – 291Polar residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TUBGCP family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2000, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157810

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002518_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G1KAD0

Identification of Orthologs from Complete Genome Data

More...
OMAi
HIRVGEN

Database of Orthologous Groups

More...
OrthoDBi
110079at2759

TreeFam database of animal gene trees

More...
TreeFami
TF106321

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.1900, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007259, GCP
IPR040457, GCP_C
IPR042241, GCP_C_sf
IPR041470, GCP_N

The PANTHER Classification System

More...
PANTHERi
PTHR19302, PTHR19302, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04130, GCP_C_terminal, 1 hit
PF17681, GCP_N_terminal, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G1KAD0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASGGPPVTD AAMESITKLF GDLCEAHSSV LSKEVHLGRG KSGKRRSIKF
60 70 80 90 100
LKKIAYNVLF ANLFLEEGRK LQPNIPKLPV KNKILMLSFN LRVAGMGPEA
110 120 130 140 150
ERLEELVDEL EKSTCLPFTE IPSVLDLLVQ LAGTGPPQCS PLKKDYFLNN
160 170 180 190 200
KYVGRNVKYQ GYDYYDVSVF EADIQAFVAN EEHHLNDTVQ KTLQMMEAAP
210 220 230 240 250
GTGLPSVELF SQNCPVGDRF ERETRVSLFG ALVHSRTYDM DIKLDLPPVP
260 270 280 290 300
DSADLSGLAI KVPQSIDPSE DEGFQSASNL TPDSQSEPSV TPDIDLWEAV
310 320 330 340 350
LTYGPSKRRC WERIGCPPGK KEEPYLSEAG REAFDKFCRL REAELQLFSS
360 370 380 390 400
NKLQLPQRVL VKESEIVKDV LNVLIGVVST SFSFNQVAQM FEVKQGLYVS
410 420 430 440 450
GTSPESMHSL LSDLAEYGTY YMRLSRFSVQ PVLDYSYKKG LVFQAFTSGL
460 470 480 490 500
RKYLQYYRAC VLSTLPTLTL LTISFLFRKL GRQLRYLADL CGIGVTSPGI
510 520 530 540 550
GGGANASFPT GVKLLSYLYQ EALNNCSNEH YPVLLSLLKT SCEPYTRFIH
560 570 580 590 600
DWVYSGVFRD AYGEFMIQVN EDYLGFRDKR YWTHGYVLIS KEVEDCVPVF
610 620 630 640 650
LKHIANDVYV CGKTINLLKL CCPRHYICWS DIPVPRISVI FSFEELKGIE
660 670 680 690 700
RDCAVYVGRM ERIARYSAIS KEEKDLRMEI EKQELIVHAR ETASKALKAF
710 720 730 740 750
TDQEISQKMA LDAKKREQFQ KLREQFEKDQ QHRHALKQEE IDENFSYARE
760 770 780 790 800
LREREKRLKA LEEDLKRRAR QELIDHYSKL SEEAAHREKK ALWKIQRHKL
810 820 830 840 850
ETARLKFLME DQKHIEEMLE KLPDGQYRRK LDIIPEYRSQ QASTGLMPVR
860 870 880 890 900
DSMLQLTPAE PVYPIVGDAE RNTGSELAND ASDKPLDVAQ PANTQATEYS
910 920 930 940 950
ELEETATQVL CTKETVPLPK SVSEQGLDFE DFLPKPQEET PAPPCITKES
960 970 980 990 1000
SLLEEALQNI SSDLSLSNQV VEGNSALKDV TEGKAVTPEY DFSTVLRPSG
1010 1020 1030 1040 1050
LQSHVKVGEN VFDVESRRPR WNIHGHASDA SIKIGEYVPG AEAAQPHSNP
1060 1070 1080 1090 1100
HGHSSDAHIR IGEYTPEEET SRPRWNIHGH VSAAHIQVGE YASDVEPSRP
1110 1120 1130 1140 1150
RWSVHGHASD ANIKIGEFVS NVEPSRPRWN IHGHMSDASI RIGENVSEVV
1160 1170 1180 1190 1200
SSRPRWNIHG HASESHFRTG ELVLDFEASK SRWNPFGHAS QSSIQVGEWT
1210 1220 1230 1240 1250
PSTDSDPIPH LKTVSGPASS STLQAFLYNG EFSAVKENDK GQEARSTDSA
1260 1270 1280 1290 1300
LGVNLDEKQE KSSGEEEEVI ISITTEDIEE PPNPPQNLQG EDTEKSTELV
1310 1320 1330 1340 1350
LVTQEICISN ASASESQEGE NAAVAMWKKE EDYLKTLSDQ YCLEEYQDNY
1360 1370 1380 1390 1400
DLMSELPVSH LLHHVIPRSF TFPLEPSAQS ATDETAVQLS ELLSLPVLMK
1410 1420 1430 1440 1450
RSVTAPLVSH VSLVNKAIVD YYFVELNVEK HFGALRHFLL MEDGEFAQSL
1460 1470 1480 1490 1500
SDLLFEKLGS GQTPGELLNP LVLNSILNKA LQYSLHGDTH LASNLSFALK
1510 1520 1530 1540 1550
YLPEMFKPNA PDALNCLELR YKVDWPLNIV ITDNCMNKYN KIFSFLLQLK
1560 1570 1580 1590 1600
HMVWTLKDVW FHLKRTALVK HASNSVQFRQ LQLYKHEMQH FVKVIQGYIA
1610 1620 1630 1640 1650
NQILHVTWCE FRNKLSSVGN LEEIYKTHAE YLNKAIFRGL LTEKAAPVMN
1660 1670 1680 1690 1700
IIHSIFSFIL KFRSQLISQS WSFDTSKQMA VHPNFGLMQQ SYNTFKYYSH
1710 1720 1730
FLFDVVTKLV NRGYQPHLED FLLRINFNNY YKDN
Length:1,734
Mass (Da):196,632
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD2D33B1976476277
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_008109427.1, XM_008111220.2
XP_016849355.1, XM_016993866.1
XP_016849356.1, XM_016993867.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSACAT00000002164; ENSACAP00000002107; ENSACAG00000002182

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100566104

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
acs:100566104

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_008109427.1, XM_008111220.2
XP_016849355.1, XM_016993866.1
XP_016849356.1, XM_016993867.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000002107

Genome annotation databases

EnsembliENSACAT00000002164; ENSACAP00000002107; ENSACAG00000002182
GeneIDi100566104
KEGGiacs:100566104

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
85378

Phylogenomic databases

eggNOGiKOG2000, Eukaryota
GeneTreeiENSGT00940000157810
HOGENOMiCLU_002518_0_0_1
InParanoidiG1KAD0
OMAiHIRVGEN
OrthoDBi110079at2759
TreeFamiTF106321

Gene expression databases

BgeeiENSACAG00000002182, Expressed in female gonad and 14 other tissues

Family and domain databases

Gene3Di1.20.120.1900, 1 hit
InterProiView protein in InterPro
IPR007259, GCP
IPR040457, GCP_C
IPR042241, GCP_C_sf
IPR041470, GCP_N
PANTHERiPTHR19302, PTHR19302, 2 hits
PfamiView protein in Pfam
PF04130, GCP_C_terminal, 1 hit
PF17681, GCP_N_terminal, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG1KAD0_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G1KAD0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: June 26, 2013
Last modified: June 2, 2021
This is version 64 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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