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UniProtKB - G1K374 (G1K374_MACMU)
Protein
Submitted name:
Forkhead box P1
Gene
FOXP1
Organism
Macaca mulatta (Rhesus macaque)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 465 – 538 | Fork-headPROSITE-ProRule annotationAdd BLAST | 74 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- metal ion binding Source: UniProtKB-KW
- sequence-specific DNA binding Source: InterPro
GO - Biological processi
- animal organ development Source: UniProt
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation, RepressorARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Forkhead box P1Submitted name: Forkhead box protein P1 isoform 1Imported |
Gene namesi | Name:FOXP1Imported |
Organismi | Macaca mulatta (Rhesus macaque)Imported |
Taxonomic identifieri | 9544 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | HostDB:ENSMMUG00000002889 |
VGNCi | VGNC:84173, FOXP1 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 465 – 538 | Fork-headInterPro annotationAdd BLAST | 74 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 43 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 270 – 298 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 390 – 422 | DisorderedSequence analysisAdd BLAST | 33 | |
Regioni | 611 – 677 | DisorderedSequence analysisAdd BLAST | 67 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 348 – 368 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 24 | Polar residuesSequence analysisAdd BLAST | 24 | |
Compositional biasi | 270 – 286 | Polar residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 390 – 405 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 611 – 625 | Polar residuesSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerARBA annotationPhylogenomic databases
eggNOGi | KOG4385, Eukaryota |
GeneTreei | ENSGT00940000159892 |
OMAi | GHAYCTP |
OrthoDBi | 836427at2759 |
TreeFami | TF326978 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR032354, FOXP-CC IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit PF16159, FOXP-CC, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
G1K374-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMQESGTETK SNGSAIQNGS GGSNHLLECG GLREGRSNGE TPAVDIGAAD
60 70 80 90 100
LAHAQQQQQQ ALQVARQLLL QQQQQQQVSG LKSPKRNDKQ PALQVPVSVA
110 120 130 140 150
MMTPQVITPQ QMQQILQQQV LSPQQLQVLL QQQQALMLQQ QQLQEFYKKQ
160 170 180 190 200
QEQLQLQLLQ QQHAGKQPKE QQQVATQQLA FQQQLLQMQQ LQQQHLLSLQ
210 220 230 240 250
RQGLLTIQPG QPALPLQPLA QGMIPTELQQ LWKEVTSAHT AEETTGNNHS
260 270 280 290 300
SLDLTTTCVS SSAPSKTSLI MNPHASTNGQ LSVHTPKRES LSHEEHPHSH
310 320 330 340 350
PLYGHGVCKW PGCEAVCEDF QSFLKHLNSE HALDDRSTAQ CRVQMQVVQQ
360 370 380 390 400
LELQLAKDKE RLQAMMTHLH VKSTEPKAAP QPLNLVSSVT LSKSASEASP
410 420 430 440 450
QSLPHTPTTP TAPLTPVTQG PSVITTTSMH TVGPIRRRYS DKYNVPISSA
460 470 480 490 500
DIAQNQEFYK NAEVRPPFTY ASLIRQAILE SPEKQLTLNE IYNWFTRMFA
510 520 530 540 550
YFRRNAATWK NAVRHNLSLH KCFVRVENVK GAVWTVDEVE FQKRRPQKIS
560 570 580 590 600
GNPSLIKNMQ SSHAYCTPLN AALQASMAEN SIPLYTTASM GNPTLGNLAS
610 620 630 640 650
AIREELNGAM EHTNSNESDS SPGRSPMQAV HPVHVKEEPL DPEEAEGPLS
660 670
LVTTANHSPD FDHDRDYEDE PVNEDME
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF7HDG5 | F7HDG5_MACMU | Forkhead box P1 | FOXP1 | 695 | Annotation score: | ||
F7HFL8 | F7HFL8_MACMU | Forkhead box P1 | FOXP1 | 676 | Annotation score: | ||
F7HFL6 | F7HFL6_MACMU | Forkhead box P1 | FOXP1 | 670 | Annotation score: | ||
F7HDH6 | F7HDH6_MACMU | Forkhead box P1 | FOXP1 | 693 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JU475179 mRNA Translation: AFH31983.1 JV046764 mRNA Translation: AFI36835.1 |
RefSeqi | NP_001253250.1, NM_001266321.1 |
Genome annotation databases
Ensembli | ENSMMUT00000011204.4; ENSMMUP00000010503.2; ENSMMUG00000002889.4 |
GeneIDi | 694726 |
KEGGi | mcc:694726 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JU475179 mRNA Translation: AFH31983.1 JV046764 mRNA Translation: AFI36835.1 |
RefSeqi | NP_001253250.1, NM_001266321.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9544.ENSMMUP00000010503 |
Genome annotation databases
Ensembli | ENSMMUT00000011204.4; ENSMMUP00000010503.2; ENSMMUG00000002889.4 |
GeneIDi | 694726 |
KEGGi | mcc:694726 |
Organism-specific databases
CTDi | 27086 |
VEuPathDBi | HostDB:ENSMMUG00000002889 |
VGNCi | VGNC:84173, FOXP1 |
Phylogenomic databases
eggNOGi | KOG4385, Eukaryota |
GeneTreei | ENSGT00940000159892 |
OMAi | GHAYCTP |
OrthoDBi | 836427at2759 |
TreeFami | TF326978 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR032354, FOXP-CC IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit PF16159, FOXP-CC, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | G1K374_MACMU | |
Accessioni | G1K374Primary (citable) accession number: G1K374 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 30, 2016 |
Last sequence update: | November 30, 2016 | |
Last modified: | May 25, 2022 | |
This is version 42 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |