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UniProtKB - G0Z2K0 (G0Z2K0_HUMAN)
Protein
Submitted name:
F-box and WD repeat domain containing 7 isoform 1
Gene
FBXW7
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: F-box and WD repeat domain containing 7 isoform 1ImportedSubmitted name: F-box and WD repeat domain containing 7 isoform 2ImportedSubmitted name: F-box and WD repeat domain containing 7 isoform 3ImportedSubmitted name: F-box and WD repeat domain containing 7 isoform 4ImportedSubmitted name: F-box and WD repeat domain containing 7 isoform 5ImportedSubmitted name: F-box and WD repeat domain containing 7 isoform 6ImportedSubmitted name: F-box and WD repeat domain containing 7 isoform 7ImportedSubmitted name: F-box/WD repeat-containing protein 7 |
Gene namesi | Name:FBXW7Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16712, FBXW7 |
VEuPathDBi | HostDB:ENSG00000109670 |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 70 | DisorderedSequence analysisAdd BLAST | 70 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 17 – 31 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 32 – 58 | Basic and acidic residuesSequence analysisAdd BLAST | 27 |
Phylogenomic databases
GeneTreei | ENSGT00940000154986 |
OrthoDBi | 927943at2759 |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
G0Z2K0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNQELLSVGS KRRRTGGSLR GNPSSSQVDE EQMNRVVEEE QQQQLRQQEE
60 70
EHTARNGEVV GVEPRPGGQN
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ969H0 | FBXW7_HUMAN | F-box/WD repeat-containing protein ... | FBXW7 FBW7, FBX30, SEL10 | 707 | Annotation score: | ||
S4R3U4 | S4R3U4_HUMAN | F-box/WD repeat-containing protein ... | FBXW7 | 176 | Annotation score: | ||
S4R3N3 | S4R3N3_HUMAN | F-box/WD repeat-containing protein ... | FBXW7 | 158 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 70 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC023424 Genomic DNA No translation available. AC080078 Genomic DNA No translation available. HQ873864 mRNA Translation: AEK48270.1 HQ873865 mRNA Translation: AEK48271.1 HQ873866 mRNA Translation: AEK48272.1 HQ873867 mRNA Translation: AEK48273.1 HQ873868 mRNA Translation: AEK48274.1 HQ873869 mRNA Translation: AEK48275.1 HQ873870 mRNA Translation: AEK48276.1 |
RefSeqi | NP_001243998.1, NM_001257069.1 |
Genome annotation databases
Ensembli | ENST00000642901.1; ENSP00000495905.1; ENSG00000109670.16 ENST00000643834.1; ENSP00000495702.1; ENSG00000109670.16 ENST00000647166.1; ENSP00000495753.1; ENSG00000109670.16 |
GeneIDi | 55294 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC023424 Genomic DNA No translation available. AC080078 Genomic DNA No translation available. HQ873864 mRNA Translation: AEK48270.1 HQ873865 mRNA Translation: AEK48271.1 HQ873866 mRNA Translation: AEK48272.1 HQ873867 mRNA Translation: AEK48273.1 HQ873868 mRNA Translation: AEK48274.1 HQ873869 mRNA Translation: AEK48275.1 HQ873870 mRNA Translation: AEK48276.1 |
RefSeqi | NP_001243998.1, NM_001257069.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 27779, 653 antibodies from 36 providers |
DNASUi | 55294 |
Genome annotation databases
Ensembli | ENST00000642901.1; ENSP00000495905.1; ENSG00000109670.16 ENST00000643834.1; ENSP00000495702.1; ENSG00000109670.16 ENST00000647166.1; ENSP00000495753.1; ENSG00000109670.16 |
GeneIDi | 55294 |
Organism-specific databases
CTDi | 55294 |
HGNCi | HGNC:16712, FBXW7 |
OpenTargetsi | ENSG00000109670 |
VEuPathDBi | HostDB:ENSG00000109670 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154986 |
OrthoDBi | 927943at2759 |
Miscellaneous databases
BioGRID-ORCSi | 55294, 75 hits in 1132 CRISPR screens |
ChiTaRSi | FBXW7, human |
GenomeRNAii | 55294 |
Family and domain databases
MobiDBi | Search... |
Entry informationi
Entry namei | G0Z2K0_HUMAN | |
Accessioni | G0Z2K0Primary (citable) accession number: G0Z2K0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 19, 2011 |
Last sequence update: | October 19, 2011 | |
Last modified: | May 25, 2022 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |