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Protein

Cytochrome c oxidase subunit 1

Gene
N/A
Organism
Picea abies (Norway spruce) (Picea excelsa)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.UniRule annotation

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.UniRule annotation

Pathwayi: oxidative phosphorylation

This protein is involved in the pathway oxidative phosphorylation, which is part of Energy metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway oxidative phosphorylation and in Energy metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transport, Respiratory chainUniRule annotation, Transport
LigandCopperUniRule annotation, HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00705

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 1UniRule annotation (EC:1.9.3.1UniRule annotation)
Encoded oniMitochondrionImported
OrganismiPicea abies (Norway spruce) (Picea excelsa)Imported
Taxonomic identifieri3329 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaPinidaePinalesPinaceaePicea

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 281COX1InterPro annotationAdd BLAST281

Sequence similaritiesi

Belongs to the heme-copper respiratory oxidase family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Family and domain databases

Gene3Di1.20.210.10, 1 hit
InterProiView protein in InterPro
IPR023616 Cyt_c_oxase-like_su1_dom
IPR036927 Cyt_c_oxase-like_su1_sf
IPR000883 Cyt_C_Oxase_1
PANTHERiPTHR10422 PTHR10422, 1 hit
PfamiView protein in Pfam
PF00115 COX1, 1 hit
PRINTSiPR01165 CYCOXIDASEI
SUPFAMiSSF81442 SSF81442, 1 hit
PROSITEiView protein in PROSITE
PS50855 COX1, 1 hit

Sequencei

Sequence statusi: Fragment.

G0YPA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SSISGAINFI TTIPNMRGPG MTMHRSPLFV RSVPVTAFLL LSSLPVPAGA
60 70 80 90 100
ITMLSTDRSF NTTFFDPAGG GDPILYQHLF RFSGHPEVHI PIPPGFGIIS
110 120 130 140 150
HIVSTFPGKP VFGYPGMVYA MISIGVPGFL VRAHHMFTVG SDVDTRAHST
160 170 180 190 200
AATMIIAVPT GIKISSRIAT MWGGSIRYKT PMLSAAGSIF PSTIGGLTGI
210 220 230 240 250
VLANPGLDIA LHDTHYVVAH SHYVLSMGAV FASSAGSHFR VGKIPGRTYP
260 270 280
ETLGQIHLRI TLFGVNSTFF PMHFLGLSGM P
Length:281
Mass (Da):29,860
Last modified:October 19, 2011 - v1
Checksum:i84A6DA827AFC717F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei281Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ727689 Genomic DNA Translation: AEK06476.1
HQ727690 Genomic DNA Translation: AEK06477.1

Similar proteinsi

Entry informationi

Entry nameiG0YPA2_PICAB
AccessioniPrimary (citable) accession number: G0YPA2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 23, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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