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Entry version 35 (26 Feb 2020)
Sequence version 1 (19 Oct 2011)
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Protein
Submitted name:

Putative NAD-dependent glutamate dehydrogenase GDH (NAD-GDH) (NAD-dependent GLUTAMIC dehydrogenase)

Gene

gdh

Organism
Mycobacterium canettii (strain CIPT 140010059)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
MCAN1048245:G1H42-2836-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative NAD-dependent glutamate dehydrogenase GDH (NAD-GDH) (NAD-dependent GLUTAMIC dehydrogenase)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gdhImported
Ordered Locus Names:MCAN_25151Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium canettii (strain CIPT 140010059)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1048245 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008896 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003404_1_1_11

KEGG Orthology (KO)

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KOi
K15371

Identification of Orthologs from Complete Genome Data

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OMAi
RATRWFL

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR028971 NAD-GDH
IPR007780 NAD_Glu_DH_bac

The PANTHER Classification System

More...
PANTHERi
PTHR43403 PTHR43403, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF05088 Bac_GDH, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036761 GDH_Mll4104, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF51735 SSF51735, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G0TPV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIDPGAKQD VEAWTTFTAS ADIPDWISKA YIDSYRGPRD DSSEATKAAE
60 70 80 90 100
ASWLPASLLT PAMLGAHYRL GRHRAAGESC VAVYRADDPA GFGPALQVVA
110 120 130 140 150
EHGGMLMDSV TVLLHRLGIA YAAILTPVFD VHRSPTGELL RIEPKAEGTS
160 170 180 190 200
PHLGEAWMHV ALSPAVDHKG LAEVERLLPK VLADVQRVAT DATALIATLS
210 220 230 240 250
ELAGEVESNA GGRFSAPDRQ DVGELLRWLG DGNFLLLGYQ RCRVADGMVY
260 270 280 290 300
GEGSSGMGVL RGRTGSRPRL TDDDKLLVLA QARVGSYLRY GAYPYAIAVR
310 320 330 340 350
EYVDGSVVEH RFVGLFSVAA MNADVLEIPT ISRRVREALA MAESDPSHPG
360 370 380 390 400
QLLLDVIQTV PRPELFTLSA QRLLTMARAV VDLGSQRQAL LFLRADRLQY
410 420 430 440 450
FVSCLVYMPR DRYTTAVRMQ FEDILVREFG GTRLEFTARV SESPWALMHF
460 470 480 490 500
MVRLPEVGVA GEGAAAPPVD VSEANRIRIQ GLLTEAARTW ADRLIGAAAA
510 520 530 540 550
TGSVGQADAM HYAAAFSEAY KQAVTPADAI GDIAVITELT DDSVKLVFSE
560 570 580 590 600
RDEQGVAQLT WFLGGRTASL SQLLPMLQSM GVVVLEERPF SVTRPDGLPV
610 620 630 640 650
WIYQFKISPH PTIPLAPTVA ERAATAHRFA EAVTAIWHGR VEIDRFNELV
660 670 680 690 700
MRAGLTWQQV VLLRAYAKYL RQAGFPYSQS YIESVLNEHP ATVRSLVDLF
710 720 730 740 750
EALFVPVPSG SASNRDAQAA AAAVAADIDA LVSLDTDRIL RAFASLVQAT
760 770 780 790 800
LRTNYFVTRQ GSARCRDVLA LKLNAQLIDE LPLPRPRYEI FVYSPRVEGV
810 820 830 840 850
HLRFGPVARG GLRWSDRRDD FRTEILGLVK AQAVKNAVIV PVGAKGGFVV
860 870 880 890 900
KRPPLPTGDP AADRDATRAE GVACYQLFIS GLLDVTDNVD HATASVNPPP
910 920 930 940 950
EVVRRDGDDA YLVVAADKGT ATFSDIANDV AKSYGFWLGD AFASGGSVGY
960 970 980 990 1000
DHKAMGITAR GAWEAVKRHF REIGIDTQTQ DFTVVGIGDM SGDVFGNGML
1010 1020 1030 1040 1050
LSKHIRLIAA FDHRHIFLDP NPDAAVSWAE RRRMFELPRS SWGDYDRSLI
1060 1070 1080 1090 1100
SEGGGVYSRE QKAIPLSAQV RAVLGIDGSV DGGAAEMAPP NLIRAILRAP
1110 1120 1130 1140 1150
VDLLFNGGIG TYIKAESESD ADVGDRANDP VRVNANQVRA KVIGEGGNLG
1160 1170 1180 1190 1200
VTALGRVEFD LSGGRINTDA LDNSAGVDCS DHEVNIKILI DSLVSAGTVK
1210 1220 1230 1240 1250
ADERTQLLES MTDEVAQLVL ADNEDQNDLM GTSRANAASL LPVHAMQIKY
1260 1270 1280 1290 1300
LVAERGVNRE LEALPSEKEI ARRSEAGIGL TSPELATLMA HVKLGLKEEV
1310 1320 1330 1340 1350
LATELPDQDV FASRLPRYFP TALRERFTPE IRSHQLRREI VTTMLINDLV
1360 1370 1380 1390 1400
DTAGITYAFR IAEDVGVTPI DAVRTYVATD AIFGVGHIWR RIRAANLPIA
1410 1420 1430 1440 1450
LSDRLTLDTR RLIDRAGRWL LNYRPQPLAV GAEINRFAAM VKALTPRMSE
1460 1470 1480 1490 1500
WLRGDDKAIV EKTAAEFASQ GVPEDLAYRV STGLYRYSLL DIIDIADIAD
1510 1520 1530 1540 1550
IDAAEVADTY FALMDRLGTD GLLTAVSQLP RHDRWHSLAR LAIRDDIYGA
1560 1570 1580 1590 1600
LRSLCFDVLA VGEPGESSEQ KIAEWEHLSA SRVARARRTL DDIRASGQKD
1610 1620
LATLSVAARQ IRRMTRTSGR GISG
Length:1,624
Mass (Da):176,900
Last modified:October 19, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDEFD5A80F0BC7257
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HE572590 Genomic DNA Translation: CCC44846.1

NCBI Reference Sequences

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RefSeqi
WP_014001286.1, NC_015848.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CCC44846; CCC44846; MCAN_25151

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mce:MCAN_25151

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE572590 Genomic DNA Translation: CCC44846.1
RefSeqiWP_014001286.1, NC_015848.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiCCC44846; CCC44846; MCAN_25151
KEGGimce:MCAN_25151

Phylogenomic databases

HOGENOMiCLU_003404_1_1_11
KOiK15371
OMAiRATRWFL

Enzyme and pathway databases

BioCyciMCAN1048245:G1H42-2836-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR028971 NAD-GDH
IPR007780 NAD_Glu_DH_bac
PANTHERiPTHR43403 PTHR43403, 1 hit
PfamiView protein in Pfam
PF05088 Bac_GDH, 1 hit
PIRSFiPIRSF036761 GDH_Mll4104, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG0TPV3_MYCCP
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G0TPV3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: February 26, 2020
This is version 35 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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