Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cadherin-9

Gene

Cdh9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cadherins are calcium-dependent cell adhesion proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionUniRule annotationSAAS annotation
LigandCalciumUniRule annotationSAAS annotation, Metal-bindingSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-418990 Adherens junctions interactions

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin-9Imported
Gene namesi
Name:Cdh9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:107433 Cdh9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei604 – 635HelicalSequence analysisAdd BLAST32

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501509137822 – 788Sequence analysisAdd BLAST767

Expressioni

Gene expression databases

BgeeiENSMUSG00000025370 Expressed in 116 organ(s), highest expression level in striatum
GenevisibleiF8WHU6 MM

Structurei

3D structure databases

ProteinModelPortaliF8WHU6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 156CAInterPro annotationAdd BLAST82
Domaini180 – 265CAInterPro annotationAdd BLAST86
Domaini289 – 381CAInterPro annotationAdd BLAST93
Domaini404 – 485CAInterPro annotationAdd BLAST82
Domaini508 – 595CAInterPro annotationAdd BLAST88

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00760000118954
KOiK06801
OMAiNNPPRFP
OrthoDBiEOG091G0298
TreeFamiTF329887

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR039808 Cadherin
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PANTHERiPTHR24027 PTHR24027, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F8WHU6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRTYSCLQLV IWTCIFHMVD NSTLQGKDSS HFLRRIVNLK KDEGKMLHRA
60 70 80 90 100
KRGWMWNQFF LLEEYTGTDT QYVGKLHTDQ DKGDGNLKYI LTGDGAGNLF
110 120 130 140 150
VIDENTGDIH AAKRLDREEK SLYILRAKAI DRKTGRQVEP ESEFIIKIHD
160 170 180 190 200
INDNEPKFTK DLYTASVPEM SGVGTSVIQV TATDADDANY GNSAKVVYSI
210 220 230 240 250
LQGQPYFSVD PESGIIKTAL PDMSRENKEQ YQVVIQAKDM GGQMGGLSGT
260 270 280 290 300
TTVNITLTDV NNNPPRFPQS TYQFNSLESA PLGTHLGRIK ANDPDMGENA
310 320 330 340 350
ELEYSIAEGE GSDMFDVITD KDTQEGIITV KQNLDFEKKM LYTLRVDASN
360 370 380 390 400
THPDPRFLHL GPFKDSAMVK ISVEDVDEPP VFSKLSYLME VDEDVKEGSI
410 420 430 440 450
IGQVTAYDPD AMNNIIKYSV DRHTDMDRVF SIHSENGSIF TLKPLDRESS
460 470 480 490 500
PWHNITITAT EINNPKQSSQ IPVFIRILDI NDHAPEFATY YETFVCENAK
510 520 530 540 550
SGQLIQTISV MDKDDPPRGH KFFFEPVPEF PLNPNFTIVD NKDNTAGIVT
560 570 580 590 600
RKDGYSRNKM NTYLLPVLIF DNDYPIQSST GTLTIRVCAC DNLGNMQSCN
610 620 630 640 650
AEALMLAAGL STGALIAILL CVVILLTLIV LFAALKRQRK KEPLIISKDD
660 670 680 690 700
VRDNIVTYND EGGGEEDTQA FDIGTLRNPE AREDSKLRRD VMPETIFQIR
710 720 730 740 750
RTVPLWENID VQDFIHRRLK ENDSDPSAPP YDSLATYAYE GNDSVANSLS
760 770 780
SLESLTADCN QDYDYLSDWG PRFKKLAEMY GGNDSDLN
Length:788
Mass (Da):88,528
Last modified:September 21, 2011 - v1
Checksum:iB8E0F9B1CE63502F
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P70407CADH9_MOUSE
Cadherin-9
Cdh9
786Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116724 Genomic DNA No translation available.
AC123645 Genomic DNA No translation available.
RefSeqiNP_033999.1, NM_009869.1
XP_006520082.1, XM_006520019.3
XP_006520083.1, XM_006520020.3
UniGeneiMm.439758

Genome annotation databases

EnsembliENSMUST00000026432; ENSMUSP00000026432; ENSMUSG00000025370
ENSMUST00000228307; ENSMUSP00000154022; ENSMUSG00000025370
GeneIDi12565
KEGGimmu:12565
UCSCiuc011zro.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116724 Genomic DNA No translation available.
AC123645 Genomic DNA No translation available.
RefSeqiNP_033999.1, NM_009869.1
XP_006520082.1, XM_006520019.3
XP_006520083.1, XM_006520020.3
UniGeneiMm.439758

3D structure databases

ProteinModelPortaliF8WHU6
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000026432; ENSMUSP00000026432; ENSMUSG00000025370
ENSMUST00000228307; ENSMUSP00000154022; ENSMUSG00000025370
GeneIDi12565
KEGGimmu:12565
UCSCiuc011zro.1 mouse

Organism-specific databases

CTDi1007
MGIiMGI:107433 Cdh9

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00760000118954
KOiK06801
OMAiNNPPRFP
OrthoDBiEOG091G0298
TreeFamiTF329887

Enzyme and pathway databases

ReactomeiR-MMU-418990 Adherens junctions interactions

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000025370 Expressed in 116 organ(s), highest expression level in striatum
GenevisibleiF8WHU6 MM

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR039808 Cadherin
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PANTHERiPTHR24027 PTHR24027, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8WHU6_MOUSE
AccessioniPrimary (citable) accession number: F8WHU6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 7, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again