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Entry version 69 (29 Sep 2021)
Sequence version 1 (21 Sep 2011)
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Protein

Golgi apparatus protein 1

Gene

Glg1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandSialic acidARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Golgi apparatus protein 1ARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Glg1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:104967, Glg1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000003316

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1131 – 1151HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500337960028 – 1163Golgi apparatus protein 1Sequence analysisAdd BLAST1136

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F8WHM5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
F8WHM5

PeptideAtlas

More...
PeptideAtlasi
F8WHM5

PRoteomics IDEntifications database

More...
PRIDEi
F8WHM5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
349533

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
F8WHM5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000003316, Expressed in striatum and 314 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F8WHM5, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati271 – 331Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST61
Repeati399 – 458Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST60
Repeati460 – 522Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST63
Repeati594 – 653Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST60
Repeati714 – 773Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST60
Repeati781 – 841Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST61
Repeati897 – 964Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST68
Repeati1026 – 1086Cys-rich GLG1PROSITE-ProRule annotationAdd BLAST61

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni30 – 83DisorderedSequence analysisAdd BLAST54
Regioni89 – 108DisorderedSequence analysisAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili649 – 669Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi53 – 83Polar residuesSequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011262

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001893, Cys-rich_GLG1_repeat
IPR017873, Cys-rich_GLG1_repeat_euk
IPR039728, GLG1

The PANTHER Classification System

More...
PANTHERi
PTHR11884, PTHR11884, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00839, Cys_rich_FGFR, 15 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51289, GLG1_C_RICH, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F8WHM5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVCGRVRGM FRLSAALPLL LLAAAGAQNG HGQGQGPGTN FGPFPGQGGG
60 70 80 90 100
GSPAGQQPPQ QPQLSQQQQQ PPPQQQQQQQ QQSLFAAGGL PARRGGAGPG
110 120 130 140 150
GTGGGWKLAE EESCREDVTR VCPKHTWSNN LAVLECLQDV RELLWNYKLN
160 170 180 190 200
LTTDPKFESV AREVCKSTIS EIKECAEEPV GKGYMVSCLV DHRGNITEYQ
210 220 230 240 250
CHQYITKMTA IIFSDYRLIC GFMDDCKNDI NLLKCGSIRL GEKDAHSQGE
260 270 280 290 300
VVSCLEKGLV KEAEEKEPKI QVSELCKKAI LRVAELSSDD FHLDRHLYFA
310 320 330 340 350
CRDDRERFCE NTQAGEGRVY KCLFNHKFEE SMSEKCREAL TTRQKLIAQD
360 370 380 390 400
YKVSYSLAKS CKSDLKKYRC NVENLPRSRE ARLSYLLMCL ESAVHRGRQV
410 420 430 440 450
SSECQGEMLD YRRMLMEDFS LSPEIILSCR GEIEHHCSGL HRKGRTLHCL
460 470 480 490 500
MKVVRGEKGN LGMNCQQALQ TLIQETDPGA DYRIDRALNE ACESVIQTAC
510 520 530 540 550
KHIRSGDPMI LSCLMEHLYT EKMVEDCEHR LLELQYFISR DWKLDPVLYR
560 570 580 590 600
KCQGDASRLC HTHGWNETSE LMPPGAVFSC LYRHAYRTEE QGRRLSRECR
610 620 630 640 650
AEVQRILHQR AMDVKLDPAL QDKCLIDLGK WCSEKTETGQ ELECLQDHLD
660 670 680 690 700
DLAVECRDIV GNLTELESED IQIEALLMRA CEPIIQNFCH DVADNQIDSG
710 720 730 740 750
DLMECLIQNK HQKDMNEKCA IGVTHFQLVQ MKDFRFSYKF KMACKEDVLK
760 770 780 790 800
LCPNIKKKVD VVICLSTTVR NDTLQEAKEH RVSLKCRKQL RVEELEMTED
810 820 830 840 850
IRLEPDLYEA CKSDIKNYCS TVQYGNAQII ECLKENKKQL STRCHQKVFK
860 870 880 890 900
LQETEMMDPE LDYTLMRVCK QMIKRFCPEA DSKTMLQCLK QNKNSELMDP
910 920 930 940 950
KCKQMITKRQ ITQNTDYRLN PVLRKACKAD IPKFCHGILT KAKDDSELEG
960 970 980 990 1000
QVISCLKLRY ADQRLSSDCE DQIRIIIQES ALDYRLDPQL QLHCSDEIAN
1010 1020 1030 1040 1050
LCAEEAAAQE QTGQVEECLK VNLLKIKTEL CKKEVLNMLK ESKADIFVDP
1060 1070 1080 1090 1100
VLHTACALDI KHHCAAITPG RGRQMSCLME ALEDKRVRLQ PECKKRLNDR
1110 1120 1130 1140 1150
IEMWSYAAKV APADGFSDLA MQVMTSPSKN YILSVISGSI CILFLIGLMC
1160
GRITKRVTRE LKD
Length:1,163
Mass (Da):132,351
Last modified:September 21, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA18EA9C9E50A0C4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q61543GSLG1_MOUSE
Golgi apparatus protein 1
Glg1 Esl1, Mg160, Selel
1,175Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PWD8E9PWD8_MOUSE
Golgi apparatus protein 1
Glg1
302Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6RSH1F6RSH1_MOUSE
Golgi apparatus protein 1
Glg1
591Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1163Imported1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000003404; ENSMUSP00000003404; ENSMUSG00000003316

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiF8WHM5

Proteomic databases

jPOSTiF8WHM5
MaxQBiF8WHM5
PeptideAtlasiF8WHM5
PRIDEiF8WHM5
ProteomicsDBi349533

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2273, 312 antibodies

Genome annotation databases

EnsembliENSMUST00000003404; ENSMUSP00000003404; ENSMUSG00000003316

Organism-specific databases

MGIiMGI:104967, Glg1
VEuPathDBiHostDB:ENSMUSG00000003316

Phylogenomic databases

GeneTreeiENSGT00390000011262

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Glg1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000003316, Expressed in striatum and 314 other tissues
ExpressionAtlasiF8WHM5, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001893, Cys-rich_GLG1_repeat
IPR017873, Cys-rich_GLG1_repeat_euk
IPR039728, GLG1
PANTHERiPTHR11884, PTHR11884, 1 hit
PfamiView protein in Pfam
PF00839, Cys_rich_FGFR, 15 hits
PROSITEiView protein in PROSITE
PS51289, GLG1_C_RICH, 8 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF8WHM5_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F8WHM5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 29, 2021
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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