UniProtKB - F8WHB5 (F8WHB5_MOUSE)
Protein
Submitted name:
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Gene
Camk2a
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- calmodulin binding Source: InterPro
- calmodulin-dependent protein kinase activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Calcium/calmodulin-dependent protein kinase type II subunit alphaImported |
Gene namesi | Name:Camk2aImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:88256, Camk2a |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 27 | Sequence analysisAdd BLAST | 27 | |
ChainiPRO_5003379505 | 28 – 189 | Sequence analysisAdd BLAST | 162 |
Proteomic databases
MaxQBi | F8WHB5 |
PeptideAtlasi | F8WHB5 |
PRIDEi | F8WHB5 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000024617, Expressed in dentate gyrus of hippocampal formation granule cell and 211 other tissues |
ExpressionAtlasi | F8WHB5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 57 – 184 | CaMKII_ADInterPro annotationAdd BLAST | 128 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 27 – 52 | DisorderedSequence analysisAdd BLAST | 26 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 33 – 52 | PolyampholyteSequence analysisAdd BLAST | 20 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000155150 |
HOGENOMi | CLU_000288_71_2_1 |
Family and domain databases
InterProi | View protein in InterPro IPR013543, Ca/CaM-dep_prot_kinase-assoc IPR032710, NTF2-like_dom_sf |
Pfami | View protein in Pfam PF08332, CaMKII_AD, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F8WHB5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLFLTLWAL VPCLVLLTLY FLSSTGGKSG GNKKNDGVKE SSESTNTTIE
60 70 80 90 100
DEDTKVRKQE IIKVTEQLIE AISNGDFESY TKMCDPGMTA FEPEALGNLV
110 120 130 140 150
EGLDFHRFYF ENLWSRNSKP VHTTILNPHI HLMGDESACI AYIRITQYLD
160 170 180
AGGIPRTAQS EETRVWHRRD GKWQIVHFHR SGAPSVLPH
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP11798 | KCC2A_MOUSE | Calcium/calmodulin-dependent protei... | Camk2a | 478 | Annotation score: | ||
F8WIS9 | F8WIS9_MOUSE | Calcium/calmodulin-dependent protei... | Camk2a | 489 | Annotation score: | ||
F6WHR9 | F6WHR9_MOUSE | Calcium/calmodulin-dependent protei... | Camk2a | 177 | Annotation score: | ||
D3Z7K9 | D3Z7K9_MOUSE | Calcium/calmodulin-dependent protei... | Camk2a | 108 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC124431 Genomic DNA No translation available. |
RefSeqi | NP_001273738.1, NM_001286809.1 |
Genome annotation databases
Ensembli | ENSMUST00000039904; ENSMUSP00000048325; ENSMUSG00000024617 |
GeneIDi | 12322 |
UCSCi | uc033hhl.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC124431 Genomic DNA No translation available. |
RefSeqi | NP_001273738.1, NM_001286809.1 |
3D structure databases
SMRi | F8WHB5 |
ModBasei | Search... |
Proteomic databases
MaxQBi | F8WHB5 |
PeptideAtlasi | F8WHB5 |
PRIDEi | F8WHB5 |
Protocols and materials databases
Antibodypediai | 3814, 847 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000039904; ENSMUSP00000048325; ENSMUSG00000024617 |
GeneIDi | 12322 |
UCSCi | uc033hhl.1, mouse |
Organism-specific databases
CTDi | 815 |
MGIi | MGI:88256, Camk2a |
Phylogenomic databases
GeneTreei | ENSGT00940000155150 |
HOGENOMi | CLU_000288_71_2_1 |
Miscellaneous databases
BioGRID-ORCSi | 12322, 1 hit in 15 CRISPR screens |
ChiTaRSi | Camk2a, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000024617, Expressed in dentate gyrus of hippocampal formation granule cell and 211 other tissues |
ExpressionAtlasi | F8WHB5, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR013543, Ca/CaM-dep_prot_kinase-assoc IPR032710, NTF2-like_dom_sf |
Pfami | View protein in Pfam PF08332, CaMKII_AD, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8WHB5_MOUSE | |
Accessioni | F8WHB5Primary (citable) accession number: F8WHB5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | December 2, 2020 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |