UniProtKB - F8WDR7 (F8WDR7_HUMAN)
Protein
Submitted name:
Actin-related protein 3
Gene
ACTR3
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
GO - Biological processi
- Arp2/3 complex-mediated actin nucleation Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Actin-related protein 3Imported |
Gene namesi | Name:ACTR3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000115091.11 |
HGNCi | HGNC:170, ACTR3 |
Subcellular locationi
Other locations
- Cell projection ARBA annotation
Cytoskeleton
- Arp2/3 protein complex Source: InterPro
Other locations
- cell projection Source: UniProtKB-SubCell
Expressioni
Gene expression databases
Bgeei | ENSG00000115091, Expressed in esophagus squamous epithelium and 245 other tissues |
ExpressionAtlasi | F8WDR7, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00940000155065 |
HOGENOMi | CLU_027965_7_5_1 |
Family and domain databases
InterProi | View protein in InterPro IPR004000, Actin IPR020902, Actin/actin-like_CS IPR015623, Arp3 IPR043129, ATPase_NBD |
PANTHERi | PTHR11937, PTHR11937, 1 hit PTHR11937:SF175, PTHR11937:SF175, 1 hit |
Pfami | View protein in Pfam PF00022, Actin, 1 hit |
SUPFAMi | SSF53067, SSF53067, 1 hit |
PROSITEi | View protein in PROSITE PS01132, ACTINS_ACT_LIKE, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F8WDR7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKGVDDLDFF IGDEAIEKPT YATKWPIRHG IVEDWDLMER FMEQVIFKYL
60 70 80
RAEPEDHYFL LTEPPLNTPE NREYTAEIMF ESFN
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP61158 | ARP3_HUMAN | Actin-related protein 3 | ACTR3 ARP3 | 418 | Annotation score: | ||
B4DXW1 | B4DXW1_HUMAN | Actin-related protein 3 | ACTR3 | 367 | Annotation score: | ||
F8WE84 | F8WE84_HUMAN | Actin-related protein 3 | ACTR3 | 41 | Annotation score: | ||
F8WEW2 | F8WEW2_HUMAN | Actin-related protein 3 | ACTR3 | 34 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 84 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC110769 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000443297; ENSP00000403125; ENSG00000115091 |
UCSCi | uc061nfe.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC110769 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | F8WDR7 |
PRIDEi | F8WDR7 |
ProteomicsDBi | 31589 |
Protocols and materials databases
Antibodypediai | 3913, 319 antibodies |
Genome annotation databases
Ensembli | ENST00000443297; ENSP00000403125; ENSG00000115091 |
UCSCi | uc061nfe.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000115091.11 |
HGNCi | HGNC:170, ACTR3 |
OpenTargetsi | ENSG00000115091 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155065 |
HOGENOMi | CLU_027965_7_5_1 |
Miscellaneous databases
ChiTaRSi | ACTR3, human |
Gene expression databases
Bgeei | ENSG00000115091, Expressed in esophagus squamous epithelium and 245 other tissues |
ExpressionAtlasi | F8WDR7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR004000, Actin IPR020902, Actin/actin-like_CS IPR015623, Arp3 IPR043129, ATPase_NBD |
PANTHERi | PTHR11937, PTHR11937, 1 hit PTHR11937:SF175, PTHR11937:SF175, 1 hit |
Pfami | View protein in Pfam PF00022, Actin, 1 hit |
SUPFAMi | SSF53067, SSF53067, 1 hit |
PROSITEi | View protein in PROSITE PS01132, ACTINS_ACT_LIKE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8WDR7_HUMAN | |
Accessioni | F8WDR7Primary (citable) accession number: F8WDR7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | October 29, 2014 | |
Last modified: | October 7, 2020 | |
This is version 49 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |