UniProtKB - F8WD60 (F8WD60_HUMAN)
Protein
Submitted name:
E3 ubiquitin-protein ligase RNF168
Gene
RNF168
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: E3 ubiquitin-protein ligase RNF168Imported |
Gene namesi | Name:RNF168Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000163961.4 |
HGNCi | HGNC:26661, RNF168 |
PTM / Processingi
Proteomic databases
MaxQBi | F8WD60 |
PeptideAtlasi | F8WD60 |
PRIDEi | F8WD60 |
ProteomicsDBi | 31386 |
Expressioni
Gene expression databases
Bgeei | ENSG00000163961, Expressed in pancreas and 213 other tissues |
ExpressionAtlasi | F8WD60, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 55 | RING-typeInterPro annotationAdd BLAST | 40 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 92 – 116 | DisorderedSequence analysisAdd BLAST | 25 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000153680 |
HOGENOMi | CLU_160798_0_0_1 |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
PROSITEi | View protein in PROSITE PS50089, ZF_RING_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F8WD60-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALPKDAIPS LSECQCGICM EILVEPVTLP CNHTLCKPCF QSTVEKASLC
60 70 80 90 100
CPFCRRRVSS WTRYHTRRNS LVNVELWTII QKHYPRECKL RASGQESEEV
110
GGGRATGQRG RRKQSQ
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ8IYW5 | RN168_HUMAN | E3 ubiquitin-protein ligase RNF168 | RNF168 | 571 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092933 Genomic DNA No translation available. AC117490 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000437070; ENSP00000396712; ENSG00000163961 |
UCSCi | uc062sbp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092933 Genomic DNA No translation available. AC117490 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | F8WD60 |
PeptideAtlasi | F8WD60 |
PRIDEi | F8WD60 |
ProteomicsDBi | 31386 |
Genome annotation databases
Ensembli | ENST00000437070; ENSP00000396712; ENSG00000163961 |
UCSCi | uc062sbp.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000163961.4 |
HGNCi | HGNC:26661, RNF168 |
OpenTargetsi | ENSG00000163961 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000153680 |
HOGENOMi | CLU_160798_0_0_1 |
Miscellaneous databases
ChiTaRSi | RNF168, human |
Gene expression databases
Bgeei | ENSG00000163961, Expressed in pancreas and 213 other tissues |
ExpressionAtlasi | F8WD60, baseline and differential |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
PROSITEi | View protein in PROSITE PS50089, ZF_RING_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8WD60_HUMAN | |
Accessioni | F8WD60Primary (citable) accession number: F8WD60 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | October 7, 2020 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |