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Protein
Submitted name:

Hepatocyte nuclear factor 4-alpha

Gene

HNF4A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatocyte nuclear factor 4-alphaImported
Gene namesi
Name:HNF4AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000101076.16
HGNCiHGNC:5024 HNF4A

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101076

PTM / Processingi

Proteomic databases

PRIDEiF8WBS7

Expressioni

Gene expression databases

BgeeiENSG00000101076 Expressed in 113 organ(s), highest expression level in liver
ExpressionAtlasiF8WBS7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8WBS7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118948

Family and domain databases

InterProiView protein in InterPro
IPR039067 HNF4A
PANTHERiPTHR24083:SF41 PTHR24083:SF41, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F8WBS7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDF VAAASRQIEA
60 70 80 90 100
SPPTSLEHIW RGGQFSTGRH VPIRRHQPQR AQQPGCQRPV CHLRGPGHGQ

TLRCLEL
Length:107
Mass (Da):11,954
Last modified:September 21, 2011 - v1
Checksum:iF13B9E01A30366B9
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P41235HNF4A_HUMAN
Hepatocyte nuclear factor 4-alpha
HNF4A HNF4, NR2A1, TCF14
474Annotation score:
A0A087WXV4A0A087WXV4_HUMAN
Hepatocyte nuclear factor 4-alpha
HNF4A
449Annotation score:
B9VVT8B9VVT8_HUMAN
HNF4alpha10/11/12
HNF4A HNF4alpha
103Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117382 Genomic DNA No translation available.
AL132772 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000372920; ENSP00000362011; ENSG00000101076
UCSCiuc061xew.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117382 Genomic DNA No translation available.
AL132772 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF8WBS7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiF8WBS7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000372920; ENSP00000362011; ENSG00000101076
UCSCiuc061xew.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000101076.16
HGNCiHGNC:5024 HNF4A
OpenTargetsiENSG00000101076
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118948

Miscellaneous databases

ChiTaRSiHNF4A human

Gene expression databases

BgeeiENSG00000101076 Expressed in 113 organ(s), highest expression level in liver
ExpressionAtlasiF8WBS7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR039067 HNF4A
PANTHERiPTHR24083:SF41 PTHR24083:SF41, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8WBS7_HUMAN
AccessioniPrimary (citable) accession number: F8WBS7
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 12, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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