UniProtKB - F8WA34 (F8WA34_HUMAN)
Protein
Acylphosphatase
Gene
ACYP2
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- EC:3.6.1.7PROSITE-ProRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 52 | PROSITE-ProRule annotation | 1 | |
Active sitei | 70 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- acylphosphatase activity Source: UniProtKB-EC
Keywordsi
Molecular function | HydrolasePROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ACYP2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000170634.12 |
HGNCi | HGNC:180, ACYP2 |
PTM / Processingi
Proteomic databases
MaxQBi | F8WA34 |
PeptideAtlasi | F8WA34 |
PRIDEi | F8WA34 |
ProteomicsDBi | 30424 |
Expressioni
Gene expression databases
Bgeei | ENSG00000170634, Expressed in quadriceps femoris and 235 other tissues |
ExpressionAtlasi | F8WA34, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 37 – 98 | Acylphosphatase-likeInterPro annotationAdd BLAST | 62 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 74 – 98 | DisorderedSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the acylphosphatase family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00390000011103 |
HOGENOMi | CLU_2503685_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR020456, Acylphosphatase IPR001792, Acylphosphatase-like_dom IPR036046, Acylphosphatase-like_dom_sf IPR017968, Acylphosphatase_CS |
PANTHERi | PTHR10029, PTHR10029, 1 hit |
Pfami | View protein in Pfam PF00708, Acylphosphatase, 1 hit |
PRINTSi | PR00112, ACYLPHPHTASE |
SUPFAMi | SSF54975, SSF54975, 1 hit |
PROSITEi | View protein in PROSITE PS00150, ACYLPHOSPHATASE_1, 1 hit PS00151, ACYLPHOSPHATASE_2, 1 hit PS51160, ACYLPHOSPHATASE_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
F8WA34-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCPLPLAAAA VAAPRAPLRL LNRGLAAAMS TAQSLKSVDY EVFGRVQGVC
60 70 80 90
FRMYTEDEAR KIGVVGWVKN TSKGTVTGQV QGPEDKVNSM NSSAPEAG
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP14621 | ACYP2_HUMAN | Acylphosphatase-2 | ACYP2 ACYP | 99 | Annotation score: | ||
U3KQL2 | U3KQL2_HUMAN | Acylphosphatase | ACYP2 | 172 | Annotation score: | ||
E9PF46 | E9PF46_HUMAN | Acylphosphatase | ACYP2 | 97 | Annotation score: | ||
U3KPX1 | U3KPX1_HUMAN | Acylphosphatase | ACYP2 | 66 | Annotation score: | ||
U3KPX8 | U3KPX8_HUMAN | Acylphosphatase-2 | ACYP2 | 83 | Annotation score: | ||
U3KQ09 | U3KQ09_HUMAN | Acylphosphatase-2 | ACYP2 | 40 | Annotation score: | ||
U3KQ94 | U3KQ94_HUMAN | Acylphosphatase-2 | ACYP2 hCG_2040114 | 116 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008068 Genomic DNA No translation available. AC008280 Genomic DNA No translation available. AC073879 Genomic DNA No translation available. AC092622 Genomic DNA No translation available. AC108929 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000303536; ENSP00000306448; ENSG00000170634 |
UCSCi | uc061jdy.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008068 Genomic DNA No translation available. AC008280 Genomic DNA No translation available. AC073879 Genomic DNA No translation available. AC092622 Genomic DNA No translation available. AC108929 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | F8WA34 |
PeptideAtlasi | F8WA34 |
PRIDEi | F8WA34 |
ProteomicsDBi | 30424 |
Protocols and materials databases
Antibodypediai | 30250, 100 antibodies |
Genome annotation databases
Ensembli | ENST00000303536; ENSP00000306448; ENSG00000170634 |
UCSCi | uc061jdy.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000170634.12 |
HGNCi | HGNC:180, ACYP2 |
OpenTargetsi | ENSG00000170634 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000011103 |
HOGENOMi | CLU_2503685_0_0_1 |
Miscellaneous databases
ChiTaRSi | ACYP2, human |
Gene expression databases
Bgeei | ENSG00000170634, Expressed in quadriceps femoris and 235 other tissues |
ExpressionAtlasi | F8WA34, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR020456, Acylphosphatase IPR001792, Acylphosphatase-like_dom IPR036046, Acylphosphatase-like_dom_sf IPR017968, Acylphosphatase_CS |
PANTHERi | PTHR10029, PTHR10029, 1 hit |
Pfami | View protein in Pfam PF00708, Acylphosphatase, 1 hit |
PRINTSi | PR00112, ACYLPHPHTASE |
SUPFAMi | SSF54975, SSF54975, 1 hit |
PROSITEi | View protein in PROSITE PS00150, ACYLPHOSPHATASE_1, 1 hit PS00151, ACYLPHOSPHATASE_2, 1 hit PS51160, ACYLPHOSPHATASE_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8WA34_HUMAN | |
Accessioni | F8WA34Primary (citable) accession number: F8WA34 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | August 12, 2020 | |
This is version 55 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |