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Entry version 71 (31 Jul 2019)
Sequence version 1 (21 Sep 2011)
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Protein
Submitted name:

Dystonin

Gene

DST

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi7101 – 7112PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi7137 – 7148PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingSAAS annotation
LigandCalciumPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DystoninImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DSTImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1090 DST

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonPROSITE-ProRule annotation

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000151914

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F8W9J4

MaxQB - The MaxQuant DataBase

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MaxQBi
F8W9J4

PeptideAtlas

More...
PeptideAtlasi
F8W9J4

PRoteomics IDEntifications database

More...
PRIDEi
F8W9J4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
30335

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
F8W9J4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000151914 Expressed in 236 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F8W9J4 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 138Calponin-homology (CH)InterPro annotationAdd BLAST104
Domaini151 – 255Calponin-homology (CH)InterPro annotationAdd BLAST105
Domaini887 – 944SH3InterPro annotationAdd BLAST58
Domaini7088 – 7123EF-handInterPro annotationAdd BLAST36
Domaini7124 – 7159EF-handInterPro annotationAdd BLAST36
Domaini7164 – 7242GARInterPro annotationAdd BLAST79

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2317 – 2346DisorderedSequence analysisAdd BLAST30
Regioni2383 – 2422DisorderedSequence analysisAdd BLAST40
Regioni2585 – 2616DisorderedSequence analysisAdd BLAST32
Regioni3190 – 3221DisorderedSequence analysisAdd BLAST32
Regioni7249 – 7270DisorderedSequence analysisAdd BLAST22
Regioni7286 – 7343DisorderedSequence analysisAdd BLAST58
Regioni7372 – 7461DisorderedSequence analysisAdd BLAST90

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili12 – 39Sequence analysisAdd BLAST28
Coiled coili459 – 479Sequence analysisAdd BLAST21
Coiled coili677 – 697Sequence analysisAdd BLAST21
Coiled coili734 – 768Sequence analysisAdd BLAST35
Coiled coili840 – 863Sequence analysisAdd BLAST24
Coiled coili1109 – 1129Sequence analysisAdd BLAST21
Coiled coili1208 – 1242Sequence analysisAdd BLAST35
Coiled coili1418 – 1448Sequence analysisAdd BLAST31
Coiled coili1504 – 1531Sequence analysisAdd BLAST28
Coiled coili3415 – 3438Sequence analysisAdd BLAST24
Coiled coili3679 – 3699Sequence analysisAdd BLAST21
Coiled coili3723 – 3757Sequence analysisAdd BLAST35
Coiled coili3843 – 3863Sequence analysisAdd BLAST21
Coiled coili3890 – 3910Sequence analysisAdd BLAST21
Coiled coili3939 – 3966Sequence analysisAdd BLAST28
Coiled coili4254 – 4274Sequence analysisAdd BLAST21
Coiled coili4346 – 4373Sequence analysisAdd BLAST28
Coiled coili4501 – 4525Sequence analysisAdd BLAST25
Coiled coili4558 – 4585Sequence analysisAdd BLAST28
Coiled coili4772 – 4806Sequence analysisAdd BLAST35
Coiled coili4813 – 4833Sequence analysisAdd BLAST21
Coiled coili4943 – 4963Sequence analysisAdd BLAST21
Coiled coili5057 – 5084Sequence analysisAdd BLAST28
Coiled coili5104 – 5131Sequence analysisAdd BLAST28
Coiled coili5204 – 5234Sequence analysisAdd BLAST31
Coiled coili5248 – 5286Sequence analysisAdd BLAST39
Coiled coili6085 – 6112Sequence analysisAdd BLAST28
Coiled coili6143 – 6163Sequence analysisAdd BLAST21
Coiled coili6191 – 6235Sequence analysisAdd BLAST45
Coiled coili6337 – 6375Sequence analysisAdd BLAST39
Coiled coili6464 – 6484Sequence analysisAdd BLAST21
Coiled coili6846 – 6876Sequence analysisAdd BLAST31
Coiled coili7054 – 7074Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2408 – 2422PolyampholyteSequence analysisAdd BLAST15
Compositional biasi2587 – 2605AcidicSequence analysisAdd BLAST19
Compositional biasi3190 – 3214PolarSequence analysisAdd BLAST25
Compositional biasi7252 – 7269PolarSequence analysisAdd BLAST18
Compositional biasi7302 – 7337PolarSequence analysisAdd BLAST36
Compositional biasi7406 – 7452PolarSequence analysisAdd BLAST47

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155008

Database of Orthologous Groups

More...
OrthoDBi
24858at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 2 hits
cd00051 EFh, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits
3.30.920.20, 1 hit
3.90.1290.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR041573 Desmoplakin_Spectrin-like
IPR029926 Dystonin-like
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR003108 GAR_dom
IPR036534 GAR_dom_sf
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR23169:SF24 PTHR23169:SF24, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 2 hits
PF13499 EF-hand_7, 1 hit
PF02187 GAS2, 1 hit
PF00681 Plectin, 2 hits
PF17902 SH3_10, 1 hit
PF00435 Spectrin, 20 hits
PF18373 Spectrin_like, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 2 hits
SM00054 EFh, 2 hits
SM00243 GAS2, 1 hit
SM00250 PLEC, 8 hits
SM00150 SPEC, 31 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF143575 SSF143575, 1 hit
SSF47473 SSF47473, 1 hit
SSF47576 SSF47576, 1 hit
SSF75399 SSF75399, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 2 hits
PS51460 GAR, 1 hit
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

F8W9J4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGYLSPAAY LYVEEQEYLQ AYEDVLERYK DERDKVQKKT FTKWINQHLM
60 70 80 90 100
KVRKHVNDLY EDLRDGHNLI SLLEVLSGDT LPREKGRMRF HRLQNVQIAL
110 120 130 140 150
DYLKRRQVKL VNIRNDDITD GNPKLTLGLI WTIILHFQIS DIHVTGESED
160 170 180 190 200
MSAKERLLLW TQQATEGYAG IRCENFTTCW RDGKLFNAII HKYRPDLIDM
210 220 230 240 250
NTVAVQSNLA NLEHAFYVAE KIGVIRLLDP EDVDVSSPDE KSVITYVSSL
260 270 280 290 300
YDAFPKVPEG GEGIGANDVE VKWIEYQNMV NYLIQWIRHH VTTMSERTFP
310 320 330 340 350
NNPVELKALY NQYLQFKETE IPPKETEKSK IKRLYKLLEI WIEFGRIKLL
360 370 380 390 400
QGYHPNDIEK EWGKLIIAML EREKALRPEV ERLEMLQQIA NRVQRDSVIC
410 420 430 440 450
EDKLILAGNA LQSDSKRLES GVQFQNEAEI AGYILECENL LRQHVIDVQI
460 470 480 490 500
LIDGKYYQAD QLVQRVAKLR DEIMALRNEC SSVYSKGRIL TTEQTKLMIS
510 520 530 540 550
GITQSLNSGF AQTLHPSLTS GLTQSLTPSL TSSSMTSGLS SGMTSRLTPS
560 570 580 590 600
VTPAYTPGFP SGLVPNFSSG VEPNSLQTLK LMQIRKPLLK SSLLDQNLTE
610 620 630 640 650
EEINMKFVQD LLNWVDEMQV QLDRTEWGSD LPSVESHLEN HKNVHRAIEE
660 670 680 690 700
FESSLKEAKI SEIQMTAPLK LTYAEKLHRL ESQYAKLLNT SRNQERHLDT
710 720 730 740 750
LHNFVSRATN ELIWLNEKEE EEVAYDWSER NTNIARKKDY HAELMRELDQ
760 770 780 790 800
KEENIKSVQE IAEQLLLENH PARLTIEAYR AAMQTQWSWI LQLCQCVEQH
810 820 830 840 850
IKENTAYFEF FNDAKEATDY LRNLKDAIQR KYSCDRSSSI HKLEDLVQES
860 870 880 890 900
MEEKEELLQY KSTIANLMGK AKTIIQLKPR NSDCPLKTSI PIKAICDYRQ
910 920 930 940 950
IEITIYKDDE CVLANNSHRA KWKVISPTGN EAMVPSVCFT VPPPNKEAVD
960 970 980 990 1000
LANRIEQQYQ NVLTLWHESH INMKSVVSWH YLINEIDRIR ASNVASIKTM
1010 1020 1030 1040 1050
LPGEHQQVLS NLQSRFEDFL EDSQESQVFS GSDITQLEKE VNVCKQYYQE
1060 1070 1080 1090 1100
LLKSAEREEQ EESVYNLYIS EVRNIRLRLE NCEDRLIRQI RTPLERDDLH
1110 1120 1130 1140 1150
ESVFRITEQE KLKKELERLK DDLGTITNKC EEFFSQAAAS SSVPTLRSEL
1160 1170 1180 1190 1200
NVVLQNMNQV YSMSSTYIDK LKTVNLVLKN TQAAEALVKL YETKLCEEEA
1210 1220 1230 1240 1250
VIADKNNIEN LISTLKQWRS EVDEKRQVFH ALEDELQKAK AISDEMFKTY
1260 1270 1280 1290 1300
KERDLDFDWH KEKADQLVER WQNVHVQIDN RLRDLEGIGK SLKYYRDTYH
1310 1320 1330 1340 1350
PLDDWIQQVE TTQRKIQENQ PENSKTLATQ LNQQKMLVSE IEMKQSKMDE
1360 1370 1380 1390 1400
CQKYAEQYSA TVKDYELQTM TYRAMVDSQQ KSPVKRRRMQ SSADLIIQEF
1410 1420 1430 1440 1450
MDLRTRYTAL VTLMTQYIKF AGDSLKRLEE EEKSLEEEKK EHVEKAKELQ
1460 1470 1480 1490 1500
KWVSNISKTL KDAEKAGKPP FSKQKISSEE ISTKKEQLSE ALQTIQLFLA
1510 1520 1530 1540 1550
KHGDKMTDEE RNELEKQVKT LQESYNLLFS ESLKQLQESQ TSGDVKVEEK
1560 1570 1580 1590 1600
LDKVIAGTID QTTGEVLSVF QAVLRGLIDY DTGIRLLETQ LMISGLISPE
1610 1620 1630 1640 1650
LRKCFDLKDA KSHGLIDEQI LCQLKELSKA KEIISAASPT TIPVLDALAQ
1660 1670 1680 1690 1700
SMITESMAIK VLEILLSTGS LVIPATGEQL TLQKAFQQNL VSSALFSKVL
1710 1720 1730 1740 1750
ERQNMCKDLI DPCTSEKVSL IDMVQRSTLQ ENTGMWLLPV RPQEGGRITL
1760 1770 1780 1790 1800
KCGRNISILR AAHEGLIDRE TMFRLLSAQL LSGGLINSNS GQRMTVEEAV
1810 1820 1830 1840 1850
REGVIDRDTA SSILTYQVQT GGIIQSNPAK RLTVDEAVQC DLITSSSALL
1860 1870 1880 1890 1900
VLEAQRGYVG LIWPHSGEIF PTSSSLQQEL ITNELAYKIL NGRQKIAALY
1910 1920 1930 1940 1950
IPESSQVIGL DAAKQLGIID NNTASILKNI TLPDKMPDLG DLEACKNARR
1960 1970 1980 1990 2000
WLSFCKFQPS TVHDYRQEED VFDGEEPVTT QTSEETKKLF LSYLMINSYM
2010 2020 2030 2040 2050
DANTGQRLLL YDGDLDEAVG MLLEGCHAEF DGNTAIKECL DVLSSSGVFL
2060 2070 2080 2090 2100
NNASGREKDE CTATPSSFNK CHCGEPEHEE TPENRKCAID EEFNEMRNTV
2110 2120 2130 2140 2150
INSEFSQSGK LASTISIDPK VNSSPSVCVP SLISYLTQTE LADISMLRSD
2160 2170 2180 2190 2200
SENILTNYEN QSRVETNERA NECSHSKNIQ NFPSDLIENP IMKSKMSKFC
2210 2220 2230 2240 2250
GVNETENEDN TNRDSPIFDY SPRLSALLSH DKLMHSQGSF NDTHTPESNG
2260 2270 2280 2290 2300
NKCEAPALSF SDKTMLSGQR IGEKFQDQFL GIAAINISLP GEQYGQKSLN
2310 2320 2330 2340 2350
MISSNPQVQY HNDKYISNTS GEDEKTHPGF QQMPEDKEDE SEIEEYSCAV
2360 2370 2380 2390 2400
TPGGDTDNAI VSLTCATPLL DETISASDYE TSLLNDQQNN TGTDTDSDDD
2410 2420 2430 2440 2450
FYDTPLFEDD DHDSLLLDGD DRDCLHPEDY DTLQEENDET ASPADVFYDV
2460 2470 2480 2490 2500
SKENENSMVP QGAPVGSLSV KNKAHCLQDF LMDVEKDELD SGEKIHLNPV
2510 2520 2530 2540 2550
GSDKVNGQSL ETGSERECTN ILEGDESDSL TDYDIVGGKE SFTASLKFDD
2560 2570 2580 2590 2600
SGSWRGRKEE YVTGQEFHSD TDHLDSMQSE ESYGDYIYDS NDQDDDDDDG
2610 2620 2630 2640 2650
IDEEGGGIRD ENGKPRCQNV AEDMDIQLCA SILNENSDEN ENINTMILLD
2660 2670 2680 2690 2700
KMHSCSSLEK QQRVNVVQLA SPSENNLVTE KSNLPEYTTE IAGKSKENLL
2710 2720 2730 2740 2750
NHEMVLKDVL PPIIKDTESE KTFGPASISH DNNNISSTSE LGTDLANTKV
2760 2770 2780 2790 2800
KLIQGSELPE LTDSVKGKDE YFKNMTPKVD SSLDHIICTE PDLIGKPAEE
2810 2820 2830 2840 2850
SHLSLIASVT DKDPQGNGSD LIKGRDGKSD ILIEDETSIQ KMYLGEGEVL
2860 2870 2880 2890 2900
VEGLVEEENR HLKLLPGKNT RDSFKLINSQ FPFPQITNNE ELNQKGSLKK
2910 2920 2930 2940 2950
ATVTLKDEPN NLQIIVSKSP VQFENLEEIF DTSVSKEISD DITSDITSWE
2960 2970 2980 2990 3000
GNTHFEESFT DGPEKELDLF TYLKHCAKNI KAKDVAKPNE DVPSHVLITA
3010 3020 3030 3040 3050
PPMKEHLQLG VNNTKEKSTS TQKDSPLNDM IQSNDLCSKE SISGGGTEIS
3060 3070 3080 3090 3100
QFTPESIEAT LSILSRKHVE DVGKNDFLQS ERCANGLGND NSSNTLNTDY
3110 3120 3130 3140 3150
SFLEINNKKE RIEQQLPKEQ ALSPRSQEKE VQIPELSQVF VEDVKDILKS
3160 3170 3180 3190 3200
RLKEGHMNPQ EVEEPSACAD TKILIQNLIK RITTSQLVNE ASTVPSDSQM
3210 3220 3230 3240 3250
SDSSGVSPMT NSSELKPESR DDPFCIGNLK SELLLNILKQ DQHSQKITGV
3260 3270 3280 3290 3300
FELMRELTHM EYDLEKRGIT SKVLPLQLEN IFYKLLADGY SEKIEHVGDF
3310 3320 3330 3340 3350
NQKACSTSEM MEEKPHILGD IKSKEGNYYS PNLETVKEIG LESSTVWAST
3360 3370 3380 3390 3400
LPRDEKLKDL CNDFPSHLEC TSGSKEMASG DSSTEQFSSE LQQCLQHTEK
3410 3420 3430 3440 3450
MHEYLTLLQD MKPPLDNQES LDNNLEALKN QLRQLETFEL GLAPIAVILR
3460 3470 3480 3490 3500
KDMKLAEEFL KSLPSDFPRG HVEELSISHQ SLKTAFSSLS NVSSERTKQI
3510 3520 3530 3540 3550
MLAIDSEMSK LAVSHEEFLH KLKSFSDWVS EKSKSVKDIE IVNVQDSEYV
3560 3570 3580 3590 3600
KKRLEFLKNV LKDLGHTKMQ LETTAFDVQF FISEYAQDLS PNQSKQLLRL
3610 3620 3630 3640 3650
LNTTQKCFLD VQESVTTQVE RLETQLHLEQ DLDDQKIVAE RQQEYKEKLQ
3660 3670 3680 3690 3700
GICDLLTQTE NRLIGHQEAF MIGDGTVELK KYQSKQEELQ KDMQGSAQAL
3710 3720 3730 3740 3750
AEVVKNTENF LKENGEKLSQ EDKALIEQKL NEAKIKCEQL NLKAEQSKKE
3760 3770 3780 3790 3800
LDKVVTTAIK EETEKVAAVK QLEESKTKIE NLLDWLSNVD KDSERAGTKH
3810 3820 3830 3840 3850
KQVIEQNGTH FQEGDGKSAI GEEDEVNGNL LETDVDGQVG TTQENLNQQY
3860 3870 3880 3890 3900
QKVKAQHEKI ISQHQAVIIA TQSAQVLLEK QGQYLSPEEK EKLQKNMKEL
3910 3920 3930 3940 3950
KVHYETALAE SEKKMKLTHS LQEELEKFDA DYTEFEHWLQ QSEQELENLE
3960 3970 3980 3990 4000
AGADDINGLM TKLKRQKSFS EDVISHKGDL RYITISGNRV LEAAKSCSKR
4010 4020 4030 4040 4050
DGGKVDTSAT HREVQRKLDH ATDRFRSLYS KCNVLGNNLK DLVDKYQHYE
4060 4070 4080 4090 4100
DASCGLLAGL QACEATASKH LSEPIAVDPK NLQRQLEETK ALQGQISSQQ
4110 4120 4130 4140 4150
VAVEKLKKTA EVLLDARGSL LPAKNDIQKT LDDIVGRYED LSKSVNERNE
4160 4170 4180 4190 4200
KLQITLTRSL SVQDGLDEML DWMGNVESSL KEQGQVPLNS TALQDIISKN
4210 4220 4230 4240 4250
IMLEQDIAGR QSSINAMNEK VKKFMETTDP STASSLQAKM KDLSARFSEA
4260 4270 4280 4290 4300
SHKHKETLAK MEELKTKVEL FENLSEKLQT FLETKTQALT EVDVPGKDVT
4310 4320 4330 4340 4350
ELSQYMQEST SEFLEHKKHL EVLHSLLKEI SSHGLPSDKA LVLEKTNNLS
4360 4370 4380 4390 4400
KKFKEMEDTI KEKKEAVTSC QEQLDAFQVL VKSLKSWIKE TTKKVPIVQP
4410 4420 4430 4440 4450
SFGAEDLGKS LEDTKKLQEK WSLKTPEIQK VNNSGISLCN LISAVTTPAK
4460 4470 4480 4490 4500
AIAAVKSGGA VLNGEGTATN TEEFWANKGL TSIKKDMTDI SHGYEDLGLL
4510 4520 4530 4540 4550
LKDKIAELNT KLSKLQKAQE ESSAMMQWLQ KMNKTATKWQ QTPAPTDTEA
4560 4570 4580 4590 4600
VKTQVEQNKS FEAELKQNVN KVQELKDKLT ELLEENPDTP EAPRWKQMLT
4610 4620 4630 4640 4650
EIDSKWQELN QLTIDRQQKL EESSNNLTQF QTVEAQLKQW LVEKELMVSV
4660 4670 4680 4690 4700
LGPLSIDPNM LNTQRQQVQI LLQEFATRKP QYEQLTAAGQ GILSRPGEDP
4710 4720 4730 4740 4750
SLRGIVKEQL AAVTQKWDSL TGQLSDRCDW IDQAIVKSTQ YQSLLRSLSD
4760 4770 4780 4790 4800
KLSDLDNKLS SSLAVSTHPD AMNQQLETAQ KMKQEIQQEK KQIKVAQALC
4810 4820 4830 4840 4850
EDLSALVKEE YLKAELSRQL EGILKSFKDV EQKAENHVQH LQSACASSHQ
4860 4870 4880 4890 4900
FQQMSRDFQA WLDTKKEEQN KSHPISAKLD VLESLIKDHK DFSKTLTAQS
4910 4920 4930 4940 4950
HMYEKTIAEG ENLLLKTQGS EKAALQLQLN TIKTNWDTFN KQVKERENKL
4960 4970 4980 4990 5000
KESLEKALKY KEQVETLWPW IDKCQNNLEE IKFCLDPAEG ENSIAKLKSL
5010 5020 5030 5040 5050
QKEMDQHFGM VELLNNTANS LLSVCEIDKE VVTDENKSLI QKVDMVTEQL
5060 5070 5080 5090 5100
HSKKFCLENM TQKFKEFQEV SKESKRQLQC AKEQLDIHDS LGSQAYSNKY
5110 5120 5130 5140 5150
LTMLQTQQKS LQALKHQVDL AKRLAQDLVV EASDSKGTSD VLLQVETIAQ
5160 5170 5180 5190 5200
EHSTLSQQVD EKCSFLETKL QGIGHFQNTI REMFSQFAEF DDELDSMAPV
5210 5220 5230 5240 5250
GRDAETLQKQ KETIKAFLKK LEALMASNDN ANKTCKMMLA TEETSPDLVG
5260 5270 5280 5290 5300
IKRDLEALSK QCNKLLDRAQ AREEQVEGTI KRLEEFYSKL KEFSILLQKA
5310 5320 5330 5340 5350
EEHEESQGPV GMETETINQQ LNMFKVFQKE EIEPLQGKQQ DVNWLGQGLI
5360 5370 5380 5390 5400
QSAAKSTSTQ GLEHDLDDVN ARWKTLNKKV AQRAAQLQEA LLHCGRFQDA
5410 5420 5430 5440 5450
LESLLSWMVD TEELVANQKP PSAEFKVVKA QIQEQKLLQR LLDDRKSTVE
5460 5470 5480 5490 5500
VIKREGEKIA TTAEPADKVK ILKQLSLLDS RWEALLNKAE TRNRQLEGIS
5510 5520 5530 5540 5550
VVAQQFHETL EPLNEWLTTI EKRLVNCEPI GTQASKLEEQ IAQHKVLQED
5560 5570 5580 5590 5600
ILLRKQNVDQ ALLNGLELLK QTTGDEVLII QDKLEAIKAR YKDITKLSTD
5610 5620 5630 5640 5650
VAKTLEQALQ LARRLHSTHE ELCTWLDKVE VELLSYETQV LKGEEASQAQ
5660 5670 5680 5690 5700
MRPKELKKEA KNNKALLDSL NEVSSALLEL VPWRAREGLE KMVAEDNERY
5710 5720 5730 5740 5750
RLVSDTITQK VEEIDAAILR SQQFDQAADA ELSWITETEK KLMSLGDIRL
5760 5770 5780 5790 5800
EQDQTSAQLQ VQKTFTMEIL RHKDIIDDLV KSGHKIMTAC SEEEKQSMKK
5810 5820 5830 5840 5850
KLDKVLKNYD TICQINSERY LQLERAQSLV NQFWETYEEL WPWLTETQSI
5860 5870 5880 5890 5900
ISQLPAPALE YETLRQQQEE HRQLRELIAE HKPHIDKMNK TGPQLLELSP
5910 5920 5930 5940 5950
GEGFSIQEKY VAADTLYSQI KEDVKKRAVA LDEAISQSTQ FHDKIDQILE
5960 5970 5980 5990 6000
SLERIVERLR QPPSISAEVE KIKEQISENK NVSVDMEKLQ PLYETLKQRG
6010 6020 6030 6040 6050
EEMIARSGGT DKDISAKAVQ DKLDQMVFIW ENIHTLVEER EAKLLDVMEL
6060 6070 6080 6090 6100
AEKFWCDHMS LIVTIKDTQD FIRDLEDPGI DPSVVKQQQE AAETIREEID
6110 6120 6130 6140 6150
GLQEELDIVI NLGSELIAAC GEPDKPIVKK SIDELNSAWD SLNKAWKDRI
6160 6170 6180 6190 6200
DKLEEAMQAA VQYQDGLQAV FDWVDIAGGK LASMSPIGTD LETVKQQIEE
6210 6220 6230 6240 6250
LKQFKSEAYQ QQIEMERLNH QAELLLKKVT EESDKHTVQD PLMELKLIWD
6260 6270 6280 6290 6300
SLEERIINRQ HKLEGALLAL GQFQHALDEL LAWLTHTEGL LSEQKPVGGD
6310 6320 6330 6340 6350
PKAIEIELAK HHVLQNDVLA HQSTVEAVNK AGNDLIESSA GEEASNLQNK
6360 6370 6380 6390 6400
LEVLNQRWQN VLEKTEQRKQ QLDGALRQAK GFHGEIEDLQ QWLTDTERHL
6410 6420 6430 6440 6450
LASKPLGGLP ETAKEQLNVH MEVCAAFEAK EETYKSLMQK GQQMLARCPK
6460 6470 6480 6490 6500
SAETNIDQDI NNLKEKWESV ETKLNERKTK LEEALNLAME FHNSLQDFIN
6510 6520 6530 6540 6550
WLTQAEQTLN VASRPSLILD TVLFQIDEHK VFANEVNSHR EQIIELDKTG
6560 6570 6580 6590 6600
THLKYFSQKQ DVVLIKNLLI SVQSRWEKVV QRLVERGRSL DDARKRAKQF
6610 6620 6630 6640 6650
HEAWSKLMEW LEESEKSLDS ELEIANDPDK IKTQLAQHKE FQKSLGAKHS
6660 6670 6680 6690 6700
VYDTTNRTGR SLKEKTSLAD DNLKLDDMLS ELRDKWDTIC GKSVERQNKL
6710 6720 6730 6740 6750
EEALLFSGQF TDALQALIDW LYRVEPQLAE DQPVHGDIDL VMNLIDNHKA
6760 6770 6780 6790 6800
FQKELGKRTS SVQALKRSAR ELIEGSRDDS SWVKVQMQEL STRWETVCAL
6810 6820 6830 6840 6850
SISKQTRLEA ALRQAEEFHS VVHALLEWLA EAEQTLRFHG VLPDDEDALR
6860 6870 6880 6890 6900
TLIDQHKEFM KKLEEKRAEL NKATTMGDTV LAICHPDSIT TIKHWITIIR
6910 6920 6930 6940 6950
ARFEEVLAWA KQHQQRLASA LAGLIAKQEL LEALLAWLQW AETTLTDKDK
6960 6970 6980 6990 7000
EVIPQEIEEV KALIAEHQTF MEEMTRKQPD VDKVTKTYKR RAADPSSLQS
7010 7020 7030 7040 7050
HIPVLDKGRA GRKRFPASSL YPSGSQTQIE TKNPRVNLLV SKWQQVWLLA
7060 7070 7080 7090 7100
LERRRKLNDA LDRLEELREF ANFDFDIWRK KYMRWMNHKK SRVMDFFRRI
7110 7120 7130 7140 7150
DKDQDGKITR QEFIDGILSS KFPTSRLEMS AVADIFDRDG DGYIDYYEFV
7160 7170 7180 7190 7200
AALHPNKDAY KPITDADKIE DEVTRQVAKC KCAKRFQVEQ IGDNKYRFFL
7210 7220 7230 7240 7250
GNQFGDSQQL RLVRILRSTV MVRVGGGWMA LDEFLVKNDP CRVHHHGSKM
7260 7270 7280 7290 7300
LRSESNSSIT TTQPTIAKGR TNMELREKFI LADGASQGMA AFRPRGRRSR
7310 7320 7330 7340 7350
PSSRGASPNR STSVSSQAAQ AASPQVPATT TPKGTPIQGS KLRLPGYLSG
7360 7370 7380 7390 7400
KGFHSGEDSG LITTAAARVR TQFADSKKTP SRPGSRAGSK AGSRASSRRG
7410 7420 7430 7440 7450
SDASDFDISE IQSVCSDVET VPQTHRPTPR AGSRPSTAKP SKIPTPQRKS
7460
PASKLDKSSK R
Length:7,461
Mass (Da):847,971
Last modified:September 21, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i96DC92B65F844758
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q03001DYST_HUMAN
Dystonin
DST BP230, BP240, BPAG1, DMH, DT
7,570Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PHM6E9PHM6_HUMAN
Dystonin
DST
5,497Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6QMI7F6QMI7_HUMAN
Dystonin
DST
5,537Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RQJ2A0A0U1RQJ2_HUMAN
Dystonin
DST
2,676Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C073A0A494C073_HUMAN
Dystonin
DST
1,347Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1U5A0A494C1U5_HUMAN
Dystonin
DST
625Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5T0V7Q5T0V7_HUMAN
Dystonin
DST
689Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7ETB9E7ETB9_HUMAN
Dystonin
DST
1,479Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1D7A0A494C1D7_HUMAN
Dystonin
DST
2,383Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6P0N6Q6P0N6_HUMAN
DST protein
DST
1,143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL096710 Genomic DNA No translation available.
AL137008 Genomic DNA No translation available.
AL512422 Genomic DNA No translation available.
AL512448 Genomic DNA No translation available.
AL590005 Genomic DNA No translation available.
AL590037 Genomic DNA No translation available.
KF458172 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_011513128.1, XM_011514826.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361203; ENSP00000354508; ENSG00000151914

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
667

UCSC genome browser

More...
UCSCi
uc063peq.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096710 Genomic DNA No translation available.
AL137008 Genomic DNA No translation available.
AL512422 Genomic DNA No translation available.
AL512448 Genomic DNA No translation available.
AL590005 Genomic DNA No translation available.
AL590037 Genomic DNA No translation available.
KF458172 Genomic DNA No translation available.
RefSeqiXP_011513128.1, XM_011514826.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiF8W9J4

Proteomic databases

jPOSTiF8W9J4
MaxQBiF8W9J4
PeptideAtlasiF8W9J4
PRIDEiF8W9J4
ProteomicsDBi30335

Genome annotation databases

EnsembliENST00000361203; ENSP00000354508; ENSG00000151914
GeneIDi667
UCSCiuc063peq.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
667
HGNCiHGNC:1090 DST
OpenTargetsiENSG00000151914

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000155008
OrthoDBi24858at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
DST human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
667

Gene expression databases

BgeeiENSG00000151914 Expressed in 236 organ(s), highest expression level in corpus callosum
ExpressionAtlasiF8W9J4 baseline and differential

Family and domain databases

CDDicd00014 CH, 2 hits
cd00051 EFh, 1 hit
Gene3Di1.10.418.10, 2 hits
3.30.920.20, 1 hit
3.90.1290.10, 1 hit
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR041573 Desmoplakin_Spectrin-like
IPR029926 Dystonin-like
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR003108 GAR_dom
IPR036534 GAR_dom_sf
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
PANTHERiPTHR23169:SF24 PTHR23169:SF24, 1 hit
PfamiView protein in Pfam
PF00307 CH, 2 hits
PF13499 EF-hand_7, 1 hit
PF02187 GAS2, 1 hit
PF00681 Plectin, 2 hits
PF17902 SH3_10, 1 hit
PF00435 Spectrin, 20 hits
PF18373 Spectrin_like, 1 hit
SMARTiView protein in SMART
SM00033 CH, 2 hits
SM00054 EFh, 2 hits
SM00243 GAS2, 1 hit
SM00250 PLEC, 8 hits
SM00150 SPEC, 31 hits
SUPFAMiSSF143575 SSF143575, 1 hit
SSF47473 SSF47473, 1 hit
SSF47576 SSF47576, 1 hit
SSF75399 SSF75399, 2 hits
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS00018 EF_HAND_1, 2 hits
PS50222 EF_HAND_2, 2 hits
PS51460 GAR, 1 hit
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF8W9J4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F8W9J4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: July 31, 2019
This is version 71 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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