UniProtKB - F8W9I4 (F8W9I4_HUMAN)
Protein
Submitted name:
Afadin
Gene
AFDN
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: AfadinImported |
Gene namesi | Name:AFDNImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000130396.20 |
HGNCi | HGNC:7137, AFDN |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: HPA
Other locations
- cell junction Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000130396, Expressed in oviduct epithelium and 216 other tissues |
ExpressionAtlasi | F8W9I4, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 39 – 134 | Ras-associatingInterPro annotationAdd BLAST | 96 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 129 – 247 | DisorderedSequence analysisAdd BLAST | 119 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 144 – 202 | PolyampholyteSequence analysisAdd BLAST | 59 | |
Compositional biasi | 220 – 247 | PolyampholyteSequence analysisAdd BLAST | 28 |
Phylogenomic databases
GeneTreei | ENSGT00940000155237 |
HOGENOMi | CLU_062698_1_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR000159, RA_dom IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF00788, RA, 1 hit |
SMARTi | View protein in SMART SM00314, RA, 1 hit |
SUPFAMi | SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS50200, RA, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All
F8W9I4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAGGRDEER RKLADIIHHW NANRLDLFEI SQPTEDLEFH GVMRFYFQDK
60 70 80 90 100
AAGNFATKCI RVSSTATTQD VIETLAEKFR PDMRMLSSPK YSLYEVHVSG
110 120 130 140 150
EERRLDIDEK PLVVQLNWNK DDREGRFVLK NENDAIPPKK AQSNGPEKQE
160 170 180 190 200
KEGVIQNFKR TLSKKEKKEK KKREKEALRQ ASDKDDRPFQ GEDVENSRLA
210 220 230 240
AEVYKDMPET SFTRTISNPE VVMKRRRQQK LEKRMQEFRS SDGRPDS
Computationally mapped potential isoform sequencesi
There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP55196 | AFAD_HUMAN | Afadin | AFDN AF6, MLLT4 | 1,824 | Annotation score: | ||
A8MQ02 | A8MQ02_HUMAN | Afadin | AFDN | 1,781 | Annotation score: | ||
J3KN01 | J3KN01_HUMAN | Afadin | AFDN | 1,831 | Annotation score: | ||
Q5TIG5 | Q5TIG5_HUMAN | Afadin | AFDN | 1,665 | Annotation score: | ||
H0Y7R8 | H0Y7R8_HUMAN | Afadin | AFDN | 389 | Annotation score: | ||
E9PFY5 | E9PFY5_HUMAN | Afadin | AFDN | 250 | Annotation score: | ||
H0YA98 | H0YA98_HUMAN | Afadin | AFDN | 167 | Annotation score: | ||
H0Y8L4 | H0Y8L4_HUMAN | Afadin | AFDN | 313 | Annotation score: | ||
H0Y8U8 | H0Y8U8_HUMAN | Afadin | AFDN | 124 | Annotation score: | ||
H0Y948 | H0Y948_HUMAN | Afadin | AFDN | 191 | Annotation score: | ||
There is more potential isoformShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 247 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009178 Genomic DNA No translation available. AL049698 Genomic DNA No translation available. AL731868 Genomic DNA No translation available. KF458344 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000400824; ENSP00000383625; ENSG00000130396 |
UCSCi | uc063sxp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009178 Genomic DNA No translation available. AL049698 Genomic DNA No translation available. AL731868 Genomic DNA No translation available. KF458344 Genomic DNA No translation available. |
3D structure databases
SMRi | F8W9I4 |
ModBasei | Search... |
Proteomic databases
MaxQBi | F8W9I4 |
PeptideAtlasi | F8W9I4 |
ProteomicsDBi | 30329 |
Protocols and materials databases
Antibodypediai | 4608, 260 antibodies |
Genome annotation databases
Ensembli | ENST00000400824; ENSP00000383625; ENSG00000130396 |
UCSCi | uc063sxp.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000130396.20 |
HGNCi | HGNC:7137, AFDN |
OpenTargetsi | ENSG00000130396 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155237 |
HOGENOMi | CLU_062698_1_0_1 |
Miscellaneous databases
ChiTaRSi | AFDN, human |
Gene expression databases
Bgeei | ENSG00000130396, Expressed in oviduct epithelium and 216 other tissues |
ExpressionAtlasi | F8W9I4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000159, RA_dom IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF00788, RA, 1 hit |
SMARTi | View protein in SMART SM00314, RA, 1 hit |
SUPFAMi | SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS50200, RA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8W9I4_HUMAN | |
Accessioni | F8W9I4Primary (citable) accession number: F8W9I4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | October 7, 2020 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |