Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Acetyl-CoA carboxylase 2

Gene

ACACB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Acetyl-CoA carboxylase 2Imported
Gene namesi
Name:ACACBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000076555.15
HGNCiHGNC:85 ACACB

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000076555

PTM / Processingi

Proteomic databases

EPDiF8W8T8
MaxQBiF8W8T8
PeptideAtlasiF8W8T8
PRIDEiF8W8T8

Expressioni

Gene expression databases

BgeeiENSG00000076555
ExpressionAtlasiF8W8T8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8W8T8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini361 – 691CoA carboxyltransferase N-terminalInterPro annotationAdd BLAST331
Domaini695 – 858CoA carboxyltransferase C-terminalInterPro annotationAdd BLAST164

Phylogenomic databases

eggNOGiKOG0368 Eukaryota
COG0439 LUCA
COG0511 LUCA
COG4799 LUCA
GeneTreeiENSGT00550000074703

Family and domain databases

InterProiView protein in InterPro
IPR034733 AcCoA_carboxyl
IPR013537 AcCoA_COase_cen
IPR029045 ClpP/crotonase-like_dom_sf
IPR011763 COA_CT_C
IPR011762 COA_CT_N
PfamiView protein in Pfam
PF08326 ACC_central, 1 hit
PF01039 Carboxyl_trans, 1 hit
SUPFAMiSSF52096 SSF52096, 2 hits
PROSITEiView protein in PROSITE
PS50989 COA_CT_CTER, 1 hit
PS50980 COA_CT_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

F8W8T8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVPISITNP DLLRHSTELF MDSGFSPLCQ RMGAMVAFRR FEDFTRNFDE
60 70 80 90 100
VISCFANVPK DTPLFSEART SLYSEDDCKS LREEPIHILN VSIQCADHLE
110 120 130 140 150
DEALVPILRT FVQSKKNILV DYGLRRITFL IAQEKEFPKF FTFRARDEFA
160 170 180 190 200
EDRIYRHLEP ALAFQLELNR MRNFDLTAVP CANHKMHLYL GAAKVKEGVE
210 220 230 240 250
VTDHRFFIRA IIRHSDLITK EASFEYLQNE GERLLLEAMD ELEVAFNNTS
260 270 280 290 300
VRTDCNHIFL NFVPTVIMDP FKIEESVRYM VMRYGSRLWK LRVLQAEVKI
310 320 330 340 350
NIRQTTTGSA VPIRLFITNE SGYYLDISLY KEVTDSRSGN IMFHSFGNKQ
360 370 380 390 400
GPQHGMLINT PYVTKDLLQA KRFQAQTLGT TYIYDFPEMF RQALFKLWGS
410 420 430 440 450
PDKYPKDILT YTELVLDSQG QLVEMNRLPG GNEVGMVAFK MRFKTQEYPE
460 470 480 490 500
GRDVIVIGND ITFRIGSFGP GEDLLYLRAS EMARAEGIPK IYVAANSGAR
510 520 530 540 550
IGMAEEIKHM FHVAWVDPED PHKGFKYLYL TPQDYTRISS LNSVHCKHIE
560 570 580 590 600
EGGESRYMIT DIIGKDDGLG VENLRGSGMI AGESSLAYEE IVTISLVTCR
610 620 630 640 650
AIGIGAYLVR LGQRVIQVEN SHIILTGASA LNKVLGREVY TSNNQLGGVQ
660 670 680 690 700
IMHYNGVSHI TVPDDFEGVY TILEWLSYMP KDNHSPVPII TPTDPIDREI
710 720 730 740 750
EFLPSRAPYD PRWMLAGRPH PTLKGTWQSG FFDHGSFKEI MAPWAQTVVT
760 770 780 790 800
GRARLGGIPV GVIAVETRTV EVAVPADPAN LDSEAKIIQQ AGQVWFPDSA
810 820 830 840 850
YKTAQAVKDF NREKLPLMIF ANWRGFSGGM KGCLGTWRDV SWWKIRAMLP

MHIGEGSV
Length:858
Mass (Da):97,372
Last modified:October 29, 2014 - v2
Checksum:i0ACCFDBC6C812B6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007637 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000377854; ENSP00000367085; ENSG00000076555
UCSCiuc058sxr.1 human

Similar proteinsi

Entry informationi

Entry nameiF8W8T8_HUMAN
AccessioniPrimary (citable) accession number: F8W8T8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: October 29, 2014
Last modified: March 28, 2018
This is version 49 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health