Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Eukaryotic translation initiation factor 2B subunit 4 delta transcript variant 4

Gene

EIF2B4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factorImported
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 2B subunit 4 delta transcript variant 4Imported
Submitted name:
Translation initiation factor eIF-2B subunit deltaImported
Gene namesi
Name:EIF2B4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000115211.15
HGNCiHGNC:3260 EIF2B4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000115211

PTM / Processingi

Proteomic databases

MaxQBiF8W8L6
PeptideAtlasiF8W8L6
PRIDEiF8W8L6

Expressioni

Gene expression databases

BgeeiENSG00000115211 Expressed in 226 organ(s), highest expression level in lower esophagus muscularis layer
ExpressionAtlasiF8W8L6 baseline and differential

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili29 – 56Sequence analysisAdd BLAST28
Coiled coili93 – 120Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1467 Eukaryota
COG1184 LUCA
GeneTreeiENSGT00550000075009

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

F8W8L6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAVAVAVRE DSGSGMKAEL PPGPGAVGRE MTKEEKLQLR KEKKQQKKKR
60 70 80 90 100
KEEKGAEPET GSAVSAAQCQ VGPTRELPES GIQLGTPREK VPAGRSKAEL
110 120 130 140 150
RAERRAKQEA ERALKQARKG EQGGPPPKAS PSTAGETPSG VKRLPEYPQV
160 170 180 190 200
DDLLLRRLVK KPERQQVPTR KDYGSKVSLF SHLPQYSRQN SLTQFMSHGA
210 220 230
TRPAVLPGPG QWLQCPVYCP ASCLAAGDSG LHNTA
Length:235
Mass (Da):25,389
Last modified:September 21, 2011 - v1
Checksum:i470492A86957AC9A
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UI10EI2BD_HUMAN
Translation initiation factor eIF-2...
EIF2B4 EIF2BD
523Annotation score:
E7ERK9E7ERK9_HUMAN
Translation initiation factor eIF-2...
EIF2B4
544Annotation score:
A0A087WTA5A0A087WTA5_HUMAN
Translation initiation factor eIF-2...
EIF2B4
520Annotation score:
H7C2L8H7C2L8_HUMAN
Translation initiation factor eIF-2...
EIF2B4
194Annotation score:
A0A087WW69A0A087WW69_HUMAN
Translation initiation factor eIF-2...
EIF2B4
228Annotation score:
F8WEV6F8WEV6_HUMAN
Translation initiation factor eIF-2...
EIF2B4
12Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC074117 Genomic DNA No translation available.
JQ991007 mRNA Translation: AFM43698.1
RefSeqiNP_001305896.1, NM_001318967.1
UniGeneiHs.169474

Genome annotation databases

EnsembliENST00000405940; ENSP00000384375; ENSG00000115211
GeneIDi8890
UCSCiuc061hop.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC074117 Genomic DNA No translation available.
JQ991007 mRNA Translation: AFM43698.1
RefSeqiNP_001305896.1, NM_001318967.1
UniGeneiHs.169474

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF8W8L6
PeptideAtlasiF8W8L6
PRIDEiF8W8L6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000405940; ENSP00000384375; ENSG00000115211
GeneIDi8890
UCSCiuc061hop.1 human

Organism-specific databases

CTDi8890
EuPathDBiHostDB:ENSG00000115211.15
HGNCiHGNC:3260 EIF2B4
OpenTargetsiENSG00000115211
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1467 Eukaryota
COG1184 LUCA
GeneTreeiENSGT00550000075009

Gene expression databases

BgeeiENSG00000115211 Expressed in 226 organ(s), highest expression level in lower esophagus muscularis layer
ExpressionAtlasiF8W8L6 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiF8W8L6_HUMAN
AccessioniPrimary (citable) accession number: F8W8L6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 12, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again