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Protein
Submitted name:

Cytohesin-2

Gene

CYTH2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Cytohesin-2Imported
Gene namesi
Name:CYTH2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000105443.13
HGNCiHGNC:9502 CYTH2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105443

PTM / Processingi

Proteomic databases

MaxQBiF8W8E2
PeptideAtlasiF8W8E2
PRIDEiF8W8E2

Expressioni

Gene expression databases

BgeeiENSG00000105443 Expressed in 224 organ(s), highest expression level in left testis
ExpressionAtlasiF8W8E2 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF8W8E2
SMRiF8W8E2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 253SEC7InterPro annotationAdd BLAST178

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili41 – 75Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0930 Eukaryota
COG5307 LUCA
GeneTreeiENSGT00760000119036

Family and domain databases

CDDicd00171 Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
InterProiView protein in InterPro
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf
PfamiView protein in Pfam
PF01369 Sec7, 1 hit
SMARTiView protein in SMART
SM00222 Sec7, 1 hit
SUPFAMiSSF48425 SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50190 SEC7, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

F8W8E2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPVVRITRS PATSPVMESE NQGLSPLPKP PDLTPEERME LENIRRRKQE
60 70 80 90 100
LLVEIQRLRE ELSEAMSEVE GLEANEGSKT LQRNRKMAMG RKKFNMDPKK
110 120 130 140 150
GIQFLVENEL LQNTPEEIAR FLYKGEGLNK TAIGDYLGER EELNLAVLHA
160 170 180 190 200
FVDLHEFTDL NLVQALRQFL WSFRLPGEAQ KIDRMMEAFA QRYCLCNPGV
210 220 230 240 250
FQSTDTCYVL SFAVIMLNTS LHNPNVRDKP GLERFVAMNR GINEGGDLPE

ELLR
Length:254
Mass (Da):29,134
Last modified:September 21, 2011 - v1
Checksum:i264D85925AD8F3BE
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99418CYH2_HUMAN
Cytohesin-2
CYTH2 ARNO, PSCD2, PSCD2L
400Annotation score:
G5E9B7G5E9B7_HUMAN
Pleckstrin homology, Sec7 and coile...
CYTH2 PSCD2, hCG_1998017
292Annotation score:
A0A0D9SFG6A0A0D9SFG6_HUMAN
Cytohesin-2
CYTH2
400Annotation score:
A0A286YF81A0A286YF81_HUMAN
Cytohesin-2
CYTH2
274Annotation score:
M0R2J0M0R2J0_HUMAN
Cytohesin-2
CYTH2
214Annotation score:
Q8WYS2Q8WYS2_HUMAN
Cytohesin-2
CYTH2 pp9943
139Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei254Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008403 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000325139; ENSP00000314566; ENSG00000105443
UCSCiuc061atu.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008403 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF8W8E2
SMRiF8W8E2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF8W8E2
PeptideAtlasiF8W8E2
PRIDEiF8W8E2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000325139; ENSP00000314566; ENSG00000105443
UCSCiuc061atu.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000105443.13
HGNCiHGNC:9502 CYTH2
OpenTargetsiENSG00000105443
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0930 Eukaryota
COG5307 LUCA
GeneTreeiENSGT00760000119036

Miscellaneous databases

ChiTaRSiCYTH2 human

Gene expression databases

BgeeiENSG00000105443 Expressed in 224 organ(s), highest expression level in left testis
ExpressionAtlasiF8W8E2 baseline and differential

Family and domain databases

CDDicd00171 Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
InterProiView protein in InterPro
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf
PfamiView protein in Pfam
PF01369 Sec7, 1 hit
SMARTiView protein in SMART
SM00222 Sec7, 1 hit
SUPFAMiSSF48425 SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50190 SEC7, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8W8E2_HUMAN
AccessioniPrimary (citable) accession number: F8W8E2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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