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Protein
Submitted name:

Voltage-gated potassium channel subunit beta-1

Gene

KCNAB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-gated potassium channel subunit beta-1Imported
Gene namesi
Name:KCNAB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000169282.17
HGNCiHGNC:6228 KCNAB1

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000169282

PTM / Processingi

Proteomic databases

MaxQBiF8W6W4
PeptideAtlasiF8W6W4
PRIDEiF8W6W4

Expressioni

Gene expression databases

BgeeiENSG00000169282 Expressed in 214 organ(s), highest expression level in putamen
ExpressionAtlasiF8W6W4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8W6W4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 172Aldo_ket_redInterPro annotationAdd BLAST87
Domaini171 – 360Aldo_ket_redInterPro annotationAdd BLAST190

Phylogenomic databases

GeneTreeiENSGT00550000074567

Family and domain databases

CDDicd06660 Aldo_ket_red, 1 hit
Gene3Di3.20.20.100, 2 hits
InterProiView protein in InterPro
IPR005399 K_chnl_volt-dep_bsu_KCNAB-rel
IPR005400 K_chnl_volt-dep_bsu_KCNAB1
IPR023210 NADP_OxRdtase_dom
IPR036812 NADP_OxRdtase_dom_sf
PfamiView protein in Pfam
PF00248 Aldo_ket_red, 2 hits
PRINTSiPR01578 KCNAB1CHANEL
PR01577 KCNABCHANNEL
SUPFAMiSSF51430 SSF51430, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

F8W6W4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQVSIACTEH NLKSRNGEDR LLSKQSSTAP NVVNAARAKF RTVAIIARSL
60 70 80 90 100
GTFTPQHHIS LKESTAKQTG MKYRNLGKSG LRVSCLGLGT WVTFGGQISD
110 120 130 140 150
EVAERLMTIA YESGVNLFDT AEVYAAGKAE VILGSIIKKK GWRRSSLVIT
160 170 180 190 200
TKLYWGGKAE TERGLSRKHI IEEIVRAMTH VINQGMAMYW GTSRWSAMEI
210 220 230 240 250
MEAYSVARQF NMIPPVCEQA EYHLFQREKV EVQLPELYHK IGVGAMTWSP
260 270 280 290 300
LACGIISGKY GNGVPESSRA SLKCYQWLKE RIVSEEGRKQ QNKLKDLSPI
310 320 330 340 350
AERLGCTLPQ LAVAWCLRNE GVSSVLLGSS TPEQLIENLG AIQVLPKMTS
360 370
HVVNEIDNIL RNKPYSKKDY RS
Length:372
Mass (Da):41,450
Last modified:September 21, 2011 - v1
Checksum:i38C108102454C9CE
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q14722KCAB1_HUMAN
Voltage-gated potassium channel sub...
KCNAB1 KCNA1B
419Annotation score:
B7Z8E5B7Z8E5_HUMAN
cDNA FLJ59247, highly similar to Vo...
KCNAB1
390Annotation score:
A0A087X1P8A0A087X1P8_HUMAN
Voltage-gated potassium channel sub...
KCNAB1
304Annotation score:
C9JQ60C9JQ60_HUMAN
Voltage-gated potassium channel sub...
KCNAB1
177Annotation score:
C9JBV8C9JBV8_HUMAN
Voltage-gated potassium channel sub...
KCNAB1
128Annotation score:
H7C4S9H7C4S9_HUMAN
Voltage-gated potassium channel sub...
KCNAB1
81Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022013 Genomic DNA No translation available.
AC067721 Genomic DNA No translation available.
AC069413 Genomic DNA No translation available.
AC084036 Genomic DNA No translation available.
AC091607 Genomic DNA No translation available.
AC092927 Genomic DNA No translation available.
AC112772 Genomic DNA No translation available.
AC125607 Genomic DNA No translation available.
RefSeqiNP_001295151.1, NM_001308222.1
UniGeneiHs.654519
Hs.703187

Genome annotation databases

EnsembliENST00000389634; ENSP00000374285; ENSG00000169282
GeneIDi7881
UCSCiuc010hvt.2 human

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022013 Genomic DNA No translation available.
AC067721 Genomic DNA No translation available.
AC069413 Genomic DNA No translation available.
AC084036 Genomic DNA No translation available.
AC091607 Genomic DNA No translation available.
AC092927 Genomic DNA No translation available.
AC112772 Genomic DNA No translation available.
AC125607 Genomic DNA No translation available.
RefSeqiNP_001295151.1, NM_001308222.1
UniGeneiHs.654519
Hs.703187

3D structure databases

ProteinModelPortaliF8W6W4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF8W6W4
PeptideAtlasiF8W6W4
PRIDEiF8W6W4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000389634; ENSP00000374285; ENSG00000169282
GeneIDi7881
UCSCiuc010hvt.2 human

Organism-specific databases

CTDi7881
EuPathDBiHostDB:ENSG00000169282.17
HGNCiHGNC:6228 KCNAB1
OpenTargetsiENSG00000169282
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00550000074567

Miscellaneous databases

ChiTaRSiKCNAB1 human
GenomeRNAii7881

Gene expression databases

BgeeiENSG00000169282 Expressed in 214 organ(s), highest expression level in putamen
ExpressionAtlasiF8W6W4 baseline and differential

Family and domain databases

CDDicd06660 Aldo_ket_red, 1 hit
Gene3Di3.20.20.100, 2 hits
InterProiView protein in InterPro
IPR005399 K_chnl_volt-dep_bsu_KCNAB-rel
IPR005400 K_chnl_volt-dep_bsu_KCNAB1
IPR023210 NADP_OxRdtase_dom
IPR036812 NADP_OxRdtase_dom_sf
PfamiView protein in Pfam
PF00248 Aldo_ket_red, 2 hits
PRINTSiPR01578 KCNAB1CHANEL
PR01577 KCNABCHANNEL
SUPFAMiSSF51430 SSF51430, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8W6W4_HUMAN
AccessioniPrimary (citable) accession number: F8W6W4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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