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UniProtKB - F8W111 (F8W111_HUMAN)
Protein
Submitted name:
Carboxypeptidase M
Gene
CPM
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- metallocarboxypeptidase activity Source: InterPro
- zinc ion binding Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Carboxypeptidase MImported |
Gene namesi | Name:CPMImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2311, CPM |
VEuPathDBi | HostDB:ENSG00000135678 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 17 | Sequence analysisAdd BLAST | 17 | |
ChainiPRO_5003379537 | 18 – 249 | Sequence analysisAdd BLAST | 232 |
Proteomic databases
MaxQBi | F8W111 |
PeptideAtlasi | F8W111 |
PRIDEi | F8W111 |
ProteomicsDBi | 29541 |
Expressioni
Gene expression databases
Bgeei | ENSG00000135678, Expressed in upper lobe of lung and 217 other tissues |
ExpressionAtlasi | F8W111, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 74 – 96 | Peptidase_M14InterPro annotationAdd BLAST | 23 | |
Domaini | 190 – 200 | Peptidase_M14InterPro annotationAdd BLAST | 11 |
Sequence similaritiesi
Belongs to the peptidase M14 family.ARBA annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000158580 |
HOGENOMi | CLU_006722_1_1_1 |
OMAi | KGQQLWV |
Family and domain databases
InterProi | View protein in InterPro IPR000834, Peptidase_M14 |
Pfami | View protein in Pfam PF00246, Peptidase_M14, 1 hit |
PRINTSi | PR00765, CRBOXYPTASEA |
SMARTi | View protein in SMART SM00631, Zn_pept, 1 hit |
PROSITEi | View protein in PROSITE PS00132, CARBOXYPEPT_ZN_1, 1 hit PS00133, CARBOXYPEPT_ZN_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
F8W111-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDFPCLWLGL LLPLVAALDF NYHRQEGMEA FLKTVAQNYS SVTHLHSIGK
60 70 80 90 100
SVKGRNLWVL VVGRFPKEHR IGIPEFKYVA NMHGDETVGR ELLLHLIDYL
110 120 130 140 150
VTSDGKDPEI TNLINSTRIH IMPSMNPDGF EAVKKPDCYY SIGRENYNQY
160 170 180 190 200
DLNRNFPDAF EYNNVSRQPE TVAVMKWLKT ETFVLSANLH GGALVASYPF
210 220 230 240
DNGVQATGAL YSRSLTPDDD VFQYLAHTYA SRNPNMKKGD ECKNKMNFP
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP14384 | CBPM_HUMAN | Carboxypeptidase M | CPM | 443 | Annotation score: | ||
F8VVI6 | F8VVI6_HUMAN | Carboxypeptidase M | CPM | 136 | Annotation score: | ||
H0YHN7 | H0YHN7_HUMAN | Carboxypeptidase M | CPM | 198 | Annotation score: | ||
H0YHG6 | H0YHG6_HUMAN | Carboxypeptidase M | CPM | 35 | Annotation score: | ||
F8VU13 | F8VU13_HUMAN | Carboxypeptidase M | CPM | 72 | Annotation score: | ||
F8VR29 | F8VR29_HUMAN | Carboxypeptidase M | CPM | 64 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 249 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025423 Genomic DNA No translation available. AC133749 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000548954; ENSP00000446799; ENSG00000135678 |
UCSCi | uc058qss.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC025423 Genomic DNA No translation available. AC133749 Genomic DNA No translation available. |
3D structure databases
SMRi | F8W111 |
ModBasei | Search... |
Proteomic databases
MaxQBi | F8W111 |
PeptideAtlasi | F8W111 |
PRIDEi | F8W111 |
ProteomicsDBi | 29541 |
Protocols and materials databases
Antibodypediai | 975, 342 antibodies from 35 providers |
Genome annotation databases
Ensembli | ENST00000548954; ENSP00000446799; ENSG00000135678 |
UCSCi | uc058qss.1, human |
Organism-specific databases
HGNCi | HGNC:2311, CPM |
OpenTargetsi | ENSG00000135678 |
VEuPathDBi | HostDB:ENSG00000135678 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158580 |
HOGENOMi | CLU_006722_1_1_1 |
OMAi | KGQQLWV |
Miscellaneous databases
ChiTaRSi | CPM, human |
Gene expression databases
Bgeei | ENSG00000135678, Expressed in upper lobe of lung and 217 other tissues |
ExpressionAtlasi | F8W111, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000834, Peptidase_M14 |
Pfami | View protein in Pfam PF00246, Peptidase_M14, 1 hit |
PRINTSi | PR00765, CRBOXYPTASEA |
SMARTi | View protein in SMART SM00631, Zn_pept, 1 hit |
PROSITEi | View protein in PROSITE PS00132, CARBOXYPEPT_ZN_1, 1 hit PS00133, CARBOXYPEPT_ZN_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F8W111_HUMAN | |
Accessioni | F8W111Primary (citable) accession number: F8W111 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | January 19, 2022 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |