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UniProtKB - F8VZY7 (F8VZY7_HUMAN)
Protein
Submitted name:
RNA-binding protein fox-1 homolog 1
Gene
RBFOX1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
GO - Biological processi
- mRNA processing Source: UniProtKB-KW
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: RNA-binding protein fox-1 homolog 1 |
Gene namesi | Name:RBFOX1 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:18222, RBFOX1 |
VEuPathDBi | HostDB:ENSG00000078328 |
Expressioni
Gene expression databases
Bgeei | ENSG00000078328, Expressed in putamen and 197 other tissues |
ExpressionAtlasi | F8VZY7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 117 – 193 | RRMInterPro annotationAdd BLAST | 77 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 121 | DisorderedSequence analysisAdd BLAST | 121 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 55 – 119 | Polar residuesSequence analysisAdd BLAST | 65 |
Phylogenomic databases
GeneTreei | ENSGT00940000160685 |
HOGENOMi | CLU_048440_1_0_1 |
OMAi | DXNAFAP |
Family and domain databases
CDDi | cd12407, RRM_FOX1_like, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR034237, FOX1_RRM IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 18 potential isoforms that are computationally mapped.Show allAlign All
F8VZY7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNCEREQLRG NQEAAAAPDT MAQPYASAQF APPQNGIPAE YTAPHPHPAP
60 70 80 90 100
EYTGQTTVPE HTLNLYPPAQ THSEQSPADT SAQTVSGTAT QTDDAAPTDG
110 120 130 140 150
QPQTQPSENT ENKSQPKRLH VSNIPFRFRD PDLRQMFGQF GKILDVEIIF
160 170 180 190 200
NERGSKGFGF VTFENSADAD RAREKLHGTV VEGRKIEVNN ATARVMTNKK
210 220 230 240 250
TVNPYTNGWK LNPVVGAVYS PEFYAGTVLL CQANQEGSSM YSAPSSLVYT
260
SAMPGFPYPA ATA
Computationally mapped potential isoform sequencesi
There are 18 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NWB1 | RFOX1_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 A2BP, A2BP1, FOX1, HRNBP1 | 397 | Annotation score: | ||
A0A6Q8PGE0 | A0A6Q8PGE0_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 A2BP1, hCG_1811870 | 354 | Annotation score: | ||
B7Z1U7 | B7Z1U7_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 425 | Annotation score: | ||
J3KNW3 | J3KNW3_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 402 | Annotation score: | ||
A0A087X2B1 | A0A087X2B1_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 375 | Annotation score: | ||
A0A6Q8PH77 | A0A6Q8PH77_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 374 | Annotation score: | ||
A0A6Q8PFM4 | A0A6Q8PFM4_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 415 | Annotation score: | ||
A0A6Q8PHA3 | A0A6Q8PHA3_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 351 | Annotation score: | ||
I3L1D4 | I3L1D4_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 372 | Annotation score: | ||
F8VRS4 | F8VRS4_HUMAN | RNA binding protein fox-1 homolog 1 | RBFOX1 | 391 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 263 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005347 Genomic DNA No translation available. AC005364 Genomic DNA No translation available. AC005563 Genomic DNA No translation available. AC005569 Genomic DNA No translation available. AC005737 Genomic DNA No translation available. AC012175 Genomic DNA No translation available. AC023822 Genomic DNA No translation available. AC074051 Genomic DNA No translation available. KF495794 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000551752.5; ENSP00000447281.1; ENSG00000078328.23 |
UCSCi | uc059qmt.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005347 Genomic DNA No translation available. AC005364 Genomic DNA No translation available. AC005563 Genomic DNA No translation available. AC005569 Genomic DNA No translation available. AC005737 Genomic DNA No translation available. AC012175 Genomic DNA No translation available. AC023822 Genomic DNA No translation available. AC074051 Genomic DNA No translation available. KF495794 Genomic DNA No translation available. |
3D structure databases
SMRi | F8VZY7 |
ModBasei | Search... |
Proteomic databases
MaxQBi | F8VZY7 |
PeptideAtlasi | F8VZY7 |
ProteomicsDBi | 29404 |
Protocols and materials databases
Antibodypediai | 24505, 375 antibodies from 32 providers |
Genome annotation databases
Ensembli | ENST00000551752.5; ENSP00000447281.1; ENSG00000078328.23 |
UCSCi | uc059qmt.1, human |
Organism-specific databases
HGNCi | HGNC:18222, RBFOX1 |
OpenTargetsi | ENSG00000078328 |
VEuPathDBi | HostDB:ENSG00000078328 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000160685 |
HOGENOMi | CLU_048440_1_0_1 |
OMAi | DXNAFAP |
Miscellaneous databases
ChiTaRSi | RBFOX1, human |
Gene expression databases
Bgeei | ENSG00000078328, Expressed in putamen and 197 other tissues |
ExpressionAtlasi | F8VZY7, baseline and differential |
Family and domain databases
CDDi | cd12407, RRM_FOX1_like, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR034237, FOX1_RRM IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F8VZY7_HUMAN | |
Accessioni | F8VZY7Primary (citable) accession number: F8VZY7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | May 25, 2022 | |
This is version 58 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |