UniProtKB - F8VZG5 (F8VZG5_HUMAN)
Protein
Nucleoside-diphosphate kinase
Gene
AK2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- nucleoside diphosphate kinase activity Source: UniProtKB-EC
Keywordsi
Molecular function | KinaseUniRule annotationARBA annotation, Transferase |
Ligand | Nucleotide-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:AK2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000004455.16 |
HGNCi | HGNC:362, AK2 |
PTM / Processingi
Proteomic databases
MaxQBi | F8VZG5 |
PeptideAtlasi | F8VZG5 |
PRIDEi | F8VZG5 |
ProteomicsDBi | 29324 |
Expressioni
Gene expression databases
Bgeei | ENSG00000004455, Expressed in adult mammalian kidney and 228 other tissues |
ExpressionAtlasi | F8VZG5, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00940000154576 |
HOGENOMi | CLU_032354_8_0_1 |
Family and domain databases
CDDi | cd01428, ADK, 1 hit |
HAMAPi | MF_00235, Adenylate_kinase_Adk, 1 hit |
InterProi | View protein in InterPro IPR000850, Adenylat/UMP-CMP_kin IPR033690, Adenylat_kinase_CS IPR027417, P-loop_NTPase |
PANTHERi | PTHR23359, PTHR23359, 1 hit |
PRINTSi | PR00094, ADENYLTKNASE |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00113, ADENYLATE_KINASE, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
F8VZG5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML
60 70 80 90 100
RAMVASGSEL GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG
110 120 130 140 150
FPRTVRQAEM LDDLMEKRKE KLDSVIEFSI PDSLLIRRIT GSIEHRNASA
160
SGHVCSDRPT LL
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP54819 | KAD2_HUMAN | Adenylate kinase 2, mitochondrial | AK2 ADK2 | 239 | Annotation score: | ||
F8W1A4 | F8W1A4_HUMAN | Adenylate kinase 2, mitochondrial | AK2 | 232 | Annotation score: | ||
F8VY04 | F8VY04_HUMAN | Nucleoside-diphosphate kinase | AK2 | 190 | Annotation score: | ||
G3V213 | G3V213_HUMAN | Nucleoside-diphosphate kinase | AK2 hCG_2032090 | 133 | Annotation score: | ||
A0A5K1VW67 | A0A5K1VW67_HUMAN | Nucleoside-diphosphate kinase | AK2 | 197 | Annotation score: | ||
A0A5F9ZHP2 | A0A5F9ZHP2_HUMAN | Nucleoside-diphosphate kinase | AK2 | 162 | Annotation score: | ||
F8VPP1 | F8VPP1_HUMAN | Nucleoside-diphosphate kinase | AK2 | 42 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL020995 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000487289; ENSP00000446849; ENSG00000004455 |
UCSCi | uc057eoa.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL020995 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | F8VZG5 |
PeptideAtlasi | F8VZG5 |
PRIDEi | F8VZG5 |
ProteomicsDBi | 29324 |
Protocols and materials databases
Antibodypediai | 17047, 445 antibodies |
Genome annotation databases
Ensembli | ENST00000487289; ENSP00000446849; ENSG00000004455 |
UCSCi | uc057eoa.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000004455.16 |
HGNCi | HGNC:362, AK2 |
OpenTargetsi | ENSG00000004455 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154576 |
HOGENOMi | CLU_032354_8_0_1 |
Miscellaneous databases
ChiTaRSi | AK2, human |
Gene expression databases
Bgeei | ENSG00000004455, Expressed in adult mammalian kidney and 228 other tissues |
ExpressionAtlasi | F8VZG5, baseline and differential |
Family and domain databases
CDDi | cd01428, ADK, 1 hit |
HAMAPi | MF_00235, Adenylate_kinase_Adk, 1 hit |
InterProi | View protein in InterPro IPR000850, Adenylat/UMP-CMP_kin IPR033690, Adenylat_kinase_CS IPR027417, P-loop_NTPase |
PANTHERi | PTHR23359, PTHR23359, 1 hit |
PRINTSi | PR00094, ADENYLTKNASE |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00113, ADENYLATE_KINASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8VZG5_HUMAN | |
Accessioni | F8VZG5Primary (citable) accession number: F8VZG5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | October 7, 2020 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |