UniProtKB - F8VX09 (F8VX09_HUMAN)
Protein
Submitted name:
Tubulin alpha-1B chain
Gene
TUBA1B
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: UniProtKB-KW
- structural constituent of cytoskeleton Source: InterPro
GO - Biological processi
- microtubule-based process Source: InterPro
Keywordsi
Ligand | GTP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Tubulin alpha-1B chainImported |
Gene namesi | Name:TUBA1BImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:18809, TUBA1B |
VEuPathDBi | HostDB:ENSG00000123416.15 |
Subcellular locationi
Cytoskeleton
- cytoskeleton ARBA annotation
Cytoskeleton
- microtubule Source: UniProtKB-KW
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonARBA annotation, MicrotubuleARBA annotationPTM / Processingi
Proteomic databases
EPDi | F8VX09 |
MaxQBi | F8VX09 |
PeptideAtlasi | F8VX09 |
PRIDEi | F8VX09 |
ProteomicsDBi | 29048 |
Expressioni
Gene expression databases
Bgeei | ENSG00000123416, Expressed in ventricular zone and 140 other tissues |
ExpressionAtlasi | F8VX09, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 9 – 75 | TubulinInterPro annotationAdd BLAST | 67 |
Sequence similaritiesi
Belongs to the tubulin family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00950000182825 |
HOGENOMi | CLU_015718_4_5_1 |
Family and domain databases
Gene3Di | 3.40.50.1440, 1 hit |
InterProi | View protein in InterPro IPR002452, Alpha_tubulin IPR000217, Tubulin IPR036525, Tubulin/FtsZ_GTPase_sf IPR003008, Tubulin_FtsZ_GTPase |
PANTHERi | PTHR11588, PTHR11588, 1 hit |
Pfami | View protein in Pfam PF00091, Tubulin, 1 hit |
PRINTSi | PR01162, ALPHATUBULIN PR01161, TUBULIN |
SUPFAMi | SSF52490, SSF52490, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
F8VX09-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPSDKTIGGG DDSFNTFFSE TGAGKHVPRA VFVDLEPTVI DEVRTGTYRQ
60 70
LFHPEQLITG KEDAANNYAR GHYTI
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP68363 | TBA1B_HUMAN | Tubulin alpha-1B chain | TUBA1B | 451 | Annotation score: | ||
F8VVB9 | F8VVB9_HUMAN | Tubulin alpha-1B chain | TUBA1B | 246 | Annotation score: | ||
F8VWV9 | F8VWV9_HUMAN | Tubulin alpha-1B chain | TUBA1B | 81 | Annotation score: | ||
F8VRK0 | F8VRK0_HUMAN | Tubulin alpha-1B chain | TUBA1B | 49 | Annotation score: | ||
F8VU66 | F8VU66_HUMAN | Tubulin alpha-1B chain | TUBA1B | 49 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 75 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011603 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000547476; ENSP00000449748; ENSG00000123416 |
UCSCi | uc058nod.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011603 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
EPDi | F8VX09 |
MaxQBi | F8VX09 |
PeptideAtlasi | F8VX09 |
PRIDEi | F8VX09 |
ProteomicsDBi | 29048 |
Protocols and materials databases
Antibodypediai | 3156, 631 antibodies |
Genome annotation databases
Ensembli | ENST00000547476; ENSP00000449748; ENSG00000123416 |
UCSCi | uc058nod.1, human |
Organism-specific databases
HGNCi | HGNC:18809, TUBA1B |
OpenTargetsi | ENSG00000123416 |
VEuPathDBi | HostDB:ENSG00000123416.15 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00950000182825 |
HOGENOMi | CLU_015718_4_5_1 |
Miscellaneous databases
ChiTaRSi | TUBA1B, human |
Gene expression databases
Bgeei | ENSG00000123416, Expressed in ventricular zone and 140 other tissues |
ExpressionAtlasi | F8VX09, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.1440, 1 hit |
InterProi | View protein in InterPro IPR002452, Alpha_tubulin IPR000217, Tubulin IPR036525, Tubulin/FtsZ_GTPase_sf IPR003008, Tubulin_FtsZ_GTPase |
PANTHERi | PTHR11588, PTHR11588, 1 hit |
Pfami | View protein in Pfam PF00091, Tubulin, 1 hit |
PRINTSi | PR01162, ALPHATUBULIN PR01161, TUBULIN |
SUPFAMi | SSF52490, SSF52490, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8VX09_HUMAN | |
Accessioni | F8VX09Primary (citable) accession number: F8VX09 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | February 10, 2021 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |