Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Bromodomain adjacent to zinc finger domain protein 2A

Gene

BAZ2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Bromodomain adjacent to zinc finger domain protein 2AImported
Gene namesi
Name:BAZ2AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000076108.11
HGNCiHGNC:962 BAZ2A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000076108

PTM / Processingi

Proteomic databases

MaxQBiF8VU39
PRIDEiF8VU39

Expressioni

Gene expression databases

BgeeiENSG00000076108 Expressed in 234 organ(s), highest expression level in cingulate cortex
ExpressionAtlasiF8VU39 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8VU39
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini544 – 615MBDInterPro annotationAdd BLAST72
Domaini846 – 911DDTInterPro annotationAdd BLAST66
Domaini1674 – 1724PHD-typeInterPro annotationAdd BLAST51
Domaini1808 – 1878BromoInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili694 – 714Sequence analysisAdd BLAST21
Coiled coili737 – 783Sequence analysisAdd BLAST47
Coiled coili1074 – 1094Sequence analysisAdd BLAST21

Keywords - Domaini

BromodomainPROSITE-ProRule annotationSAAS annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1245 Eukaryota
COG5076 LUCA
GeneTreeiENSGT00930000150850

Family and domain databases

CDDicd05503 Bromo_BAZ2A_B_like, 1 hit
Gene3Di1.20.920.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR017956 AT_hook_DNA-bd_motif
IPR037374 BAZ2A/B_Bromo
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR018501 DDT_dom
IPR016177 DNA-bd_dom_sf
IPR001739 Methyl_CpG_DNA-bd
IPR028940 TIP5
IPR028942 WHIM1_dom
IPR028941 WHIM2_dom
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR22880:SF141 PTHR22880:SF141, 1 hit
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF02791 DDT, 1 hit
PF01429 MBD, 1 hit
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit
PF15613 WSD, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00384 AT_hook, 4 hits
SM00297 BROMO, 1 hit
SM00571 DDT, 1 hit
SM00391 MBD, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF54171 SSF54171, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS50827 DDT, 1 hit
PS50982 MBD, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

F8VU39-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEANDHFNFT GLPPAPAASG LKPSPSSGEG LYTNGSPMNF PQQGKSLNGD
60 70 80 90 100
VNVNGLSTVS HTTTSGILNS APHSSSTSHL HHPSVAYDCL WNYSQYPSAN
110 120 130 140 150
PGSNLKDPPL LSQFSGGQYP LNGILGGSRQ PSSPSHNTNL RAGSQEFWAN
160 170 180 190 200
GTQSPMGLNF DSQELYDSFP DQNFEVMPNG PPSFFTSPQT SPMLGSSIQT
210 220 230 240 250
FAPSQEVGSG IHPDEAAEKE MTSVVAENGT GLVGSLELEE EQPELKMCGY
260 270 280 290 300
NGSVPSVESL HQEVSVLVPD PTVSCLDDPS HLPDQLEDTP ILSEDSLEPF
310 320 330 340 350
NSLAPEPVSG GLYGIDDTEL MGAEDKLPLE DSPVISALDC PSLNNATAFS
360 370 380 390 400
LLADDSQTST SIFASPTSPP VLGESVLQDN SFDLNNGSDA EQEEMETQSS
410 420 430 440 450
DFPPSLTQPA PDQSSTIQLH PATSPAVSPT TSPAVSLVVS PAASPEISPE
460 470 480 490 500
VCPAASTVVS PAVFSVVSPA SSAVLPAVSL EVPLTASVTS PKASPVTSPA
510 520 530 540 550
AAFPTASPAN KDVSSFLETT ADVEEITGEG LTASGSGDVM RRRIATPEEV
560 570 580 590 600
RLPLQHGWRR EVRIKKGSHR WQGETWYYGP CGKRMKQFPE VIKYLSRNVV
610 620 630 640 650
HSVRREHFSF SPRMPVGDFF EERDTPEGLQ WVQLSAEEIP SRIQAITGKR
660 670 680 690 700
GRPRNTEKAK TKEVPKVKRG RGRPPKVKIT ELLNKTDNRP LKKLEAQETL
710 720 730 740 750
NEEDKAKIAK SKKKMRQKVQ RGECQTTIQG QARNKRKQET KSLKQKEAKK
760 770 780 790 800
KSKAEKEKGK TKQEKLKEKV KREKKEKVKM KEKEEVTKAK PACKADKTLA
810 820 830 840 850
TQRRLEERQR QQMILEEMKK PTEDMCLTDH QPLPDFSRVP GLTLPSGAFS
860 870 880 890 900
DCLTIVEFLH SFGKVLGFDP AKDVPSLGVL QEGLLCQGDS LGEVQDLLVR
910 920 930 940 950
LLKAALHDPG FPSYCQSLKI LGEKVSEIPL TRDNVSEILR CFLMAYGVEP
960 970 980 990 1000
ALCDRLRTQP FQAQPPQQKA AVLAFLVHEL NGSTLIINEI DKTLESMSSY
1010 1020 1030 1040 1050
RKNKWIVEGR LRRLKTVLAK RTGRSEVEME GPEECLGRRR SSRIMEETSG
1060 1070 1080 1090 1100
MEEEEEEESI AAVPGRRGRR DGEVDATASS IPELERQIEK LSKRQLFFRK
1110 1120 1130 1140 1150
KLLHSSQMLR AVSLGQDRYR RRYWVLPYLA GIFVEGTEGN LVPEEVIKKE
1160 1170 1180 1190 1200
TDSLKVAAHA SLNPALFSMK MELAGSNTTA SSPARARGRP RKTKPGSMQP
1210 1220 1230 1240 1250
RHLKSPVRGQ DSEQPQAQLQ PEAQLHAPAQ PQPQLQLQLQ SHKGFLEQEG
1260 1270 1280 1290 1300
SPLSLGQSQH DLSQSAFLSW LSQTQSHSSL LSSSVLTPDS SPGKLDPAPS
1310 1320 1330 1340 1350
QPPEEPEPDE AESSPDPQAL WFNISAQMPC NAAPTPPPAV SEDQPTPSPQ
1360 1370 1380 1390 1400
QLASSKPMNR PSAANPCSPV QFSSTPLAGL APKRRAGDPG EMPQSPTGLG
1410 1420 1430 1440 1450
QPKRRGRPPS KFFKQMEQRY LTQLTAQPVP PEMCSGWWWI RDPEMLDAML
1460 1470 1480 1490 1500
KALHPRGIRE KALHKHLNKH RDFLQEVCLR PSADPIFEPR QLPAFQEGIM
1510 1520 1530 1540 1550
SWSPKEKTYE TDLAVLQWVE ELEQRVIMSD LQIRGWTCPS PDSTREDLAY
1560 1570 1580 1590 1600
CEHLSDSQED ITWRGRGREG LAPQRKTTNP LDLAVMRLAA LEQNVERRYL
1610 1620 1630 1640 1650
REPLWPTHEV VLEKALLSTP NGAPEGTTTE ISYEITPRIR VWRQTLERCR
1660 1670 1680 1690 1700
SAAQVCLCLG QLERSIAWEK SVNKVTCLVC RKGDNDEFLL LCDGCDRGCH
1710 1720 1730 1740 1750
IYCHRPKMEA VPEGDWFCTV CLAQQVEGEF TQKPGFPKRG QKRKSGYSLN
1760 1770 1780 1790 1800
FSEGDGRRRR VLLRGRESPA AGPRYSEEGL SPSKRRRLSM RNHHSDLTFC
1810 1820 1830 1840 1850
EIILMEMESH DAAWPFLEPV NPRLVSGYRR IIKNPMDFST MRERLLRGGY
1860 1870 1880 1890 1900
TSSEEFAADA LLVFDNCQTF NEDDSEVGKA GHIMRRFFES RWEEFYQGKQ

ANL
Length:1,903
Mass (Da):210,937
Last modified:September 21, 2011 - v1
Checksum:iB8DABA59162490D9
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UIF9BAZ2A_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A KIAA0314, TIP5
1,905Annotation score:
J3KPG5J3KPG5_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A
1,875Annotation score:
H0YII3H0YII3_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A
205Annotation score:
A0A0C4DGI9A0A0C4DGI9_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A
837Annotation score:
H0YHQ7H0YHQ7_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A
277Annotation score:
H0YHL2H0YHL2_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A
162Annotation score:
F8W053F8W053_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A
116Annotation score:
F8VWQ3F8VWQ3_HUMAN
Bromodomain adjacent to zinc finger...
BAZ2A
131Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090681 Genomic DNA No translation available.
RefSeqiNP_001287834.1, NM_001300905.1
UniGeneiHs.314263

Genome annotation databases

EnsembliENST00000549884; ENSP00000447941; ENSG00000076108
GeneIDi11176
UCSCiuc001slp.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090681 Genomic DNA No translation available.
RefSeqiNP_001287834.1, NM_001300905.1
UniGeneiHs.314263

3D structure databases

ProteinModelPortaliF8VU39
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF8VU39
PRIDEiF8VU39

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000549884; ENSP00000447941; ENSG00000076108
GeneIDi11176
UCSCiuc001slp.2 human

Organism-specific databases

CTDi11176
EuPathDBiHostDB:ENSG00000076108.11
HGNCiHGNC:962 BAZ2A
OpenTargetsiENSG00000076108
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1245 Eukaryota
COG5076 LUCA
GeneTreeiENSGT00930000150850

Miscellaneous databases

ChiTaRSiBAZ2A human
GenomeRNAii11176

Gene expression databases

BgeeiENSG00000076108 Expressed in 234 organ(s), highest expression level in cingulate cortex
ExpressionAtlasiF8VU39 baseline and differential

Family and domain databases

CDDicd05503 Bromo_BAZ2A_B_like, 1 hit
Gene3Di1.20.920.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR017956 AT_hook_DNA-bd_motif
IPR037374 BAZ2A/B_Bromo
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR018501 DDT_dom
IPR016177 DNA-bd_dom_sf
IPR001739 Methyl_CpG_DNA-bd
IPR028940 TIP5
IPR028942 WHIM1_dom
IPR028941 WHIM2_dom
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR22880:SF141 PTHR22880:SF141, 1 hit
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF02791 DDT, 1 hit
PF01429 MBD, 1 hit
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit
PF15613 WSD, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00384 AT_hook, 4 hits
SM00297 BROMO, 1 hit
SM00571 DDT, 1 hit
SM00391 MBD, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF54171 SSF54171, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS50827 DDT, 1 hit
PS50982 MBD, 1 hit
PS50016 ZF_PHD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8VU39_HUMAN
AccessioniPrimary (citable) accession number: F8VU39
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 7, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again