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Protein
Submitted name:

Nuclear transcription factor Y subunit beta

Gene

NFYB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiF8VSL3

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear transcription factor Y subunit betaImported
Gene namesi
Name:NFYBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000120837.7
HGNCiHGNC:7805 NFYB

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120837

PTM / Processingi

Proteomic databases

MaxQBiF8VSL3
PeptideAtlasiF8VSL3
PRIDEiF8VSL3

Expressioni

Gene expression databases

BgeeiENSG00000120837 Expressed in 233 organ(s), highest expression level in substantia nigra
ExpressionAtlasiF8VSL3 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiF8VSL3, 2 interactors

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 123CBFD_NFYB_HMFInterPro annotationAdd BLAST65

Phylogenomic databases

eggNOGiKOG0869 Eukaryota
COG2036 LUCA
GeneTreeiENSGT00550000074689

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR003958 CBFA_NFYB_domain
IPR009072 Histone-fold
IPR003956 Transcrpt_fac_NFYB/HAP3_CS
PfamiView protein in Pfam
PF00808 CBFD_NFYB_HMF, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS00685 NFYB_HAP3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F8VSL3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLMDGDSST TDASQLGISA DYIGGSHYVI QPHDDTEDSM NDHEDTNGSK
60 70 80 90 100
ESFREQDIYL PIANVARIMK NAIPQTGKIA KDAKECVQEC VSEFISFITS
110 120 130
EASERCHQEK RKTINGEDIL FAMSTLGFDS Y
Length:131
Mass (Da):14,548
Last modified:September 21, 2011 - v1
Checksum:i2959BA12EF3C8DC3
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P25208NFYB_HUMAN
Nuclear transcription factor Y subu...
NFYB HAP3
207Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei131Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC089983 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000551446; ENSP00000448250; ENSG00000120837
UCSCiuc058snr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC089983 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiF8VSL3, 2 interactors

Proteomic databases

MaxQBiF8VSL3
PeptideAtlasiF8VSL3
PRIDEiF8VSL3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000551446; ENSP00000448250; ENSG00000120837
UCSCiuc058snr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000120837.7
HGNCiHGNC:7805 NFYB
OpenTargetsiENSG00000120837
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0869 Eukaryota
COG2036 LUCA
GeneTreeiENSGT00550000074689

Enzyme and pathway databases

SignaLinkiF8VSL3

Miscellaneous databases

ChiTaRSiNFYB human

Gene expression databases

BgeeiENSG00000120837 Expressed in 233 organ(s), highest expression level in substantia nigra
ExpressionAtlasiF8VSL3 baseline and differential

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR003958 CBFA_NFYB_domain
IPR009072 Histone-fold
IPR003956 Transcrpt_fac_NFYB/HAP3_CS
PfamiView protein in Pfam
PF00808 CBFD_NFYB_HMF, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS00685 NFYB_HAP3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8VSL3_HUMAN
AccessioniPrimary (citable) accession number: F8VSL3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 12, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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