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Protein
Submitted name:

Suppressor of cytokine-signaling 2

Gene

SOCS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiF8VRV3

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine-signaling 2Imported
Gene namesi
Name:SOCS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000120833.13
HGNCiHGNC:19382 SOCS2

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120833

PTM / Processingi

Proteomic databases

EPDiF8VRV3
MaxQBiF8VRV3
PeptideAtlasiF8VRV3
PRIDEiF8VRV3

Expressioni

Gene expression databases

BgeeiENSG00000120833
ExpressionAtlasiF8VRV3 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF8VRV3
SMRiF8VRV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 156SH2InterPro annotationAdd BLAST109

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
GeneTreeiENSGT00760000119136

Family and domain databases

CDDicd10383 SH2_SOCS2, 1 hit
Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR028410 SOCS2
IPR035862 SOCS2_SH2
PANTHERiPTHR44396 PTHR44396, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SUPFAMiSSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit

Sequencei

Sequence statusi: Fragment.

F8VRV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRCLEPSG NGGEGTRSQW GTAGSAEEPS PQAARLAKAL RELGQTGWYW
60 70 80 90 100
GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ
110 120 130 140 150
DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL
160
YLTKPLYTSA P
Length:161
Mass (Da):17,841
Last modified:September 21, 2011 - v1
Checksum:i6C293510EE542117
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei161Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012085 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000549887; ENSP00000448611; ENSG00000120833
UCSCiuc058rtl.1 human

Similar proteinsi

Entry informationi

Entry nameiF8VRV3_HUMAN
AccessioniPrimary (citable) accession number: F8VRV3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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