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Protein
Submitted name:

DNA-directed RNA polymerase III subunit RPC2

Gene

POLR3B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-directed RNA polymerase III subunit RPC2Imported
Gene namesi
Name:POLR3BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000013503.9
HGNCiHGNC:30348 POLR3B

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000013503

PTM / Processingi

Proteomic databases

PeptideAtlasiF8VRU2
PRIDEiF8VRU2

Expressioni

Gene expression databases

BgeeiENSG00000013503 Expressed in 189 organ(s), highest expression level in endometrium
ExpressionAtlasiF8VRU2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8VRU2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 121RNA_pol_Rpb2_2InterPro annotationAdd BLAST121

Phylogenomic databases

eggNOGiKOG0215 Eukaryota
COG0085 LUCA
GeneTreeiENSGT00920000149102

Family and domain databases

Gene3Di3.90.1110.10, 1 hit
InterProiView protein in InterPro
IPR015712 DNA-dir_RNA_pol_su2
IPR007642 RNA_pol_Rpb2_2
IPR037034 RNA_pol_Rpb2_2_sf
PANTHERiPTHR20856 PTHR20856, 1 hit
PfamiView protein in Pfam
PF04561 RNA_pol_Rpb2_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F8VRU2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVESDQEIV QMIGTEEHVM AAFGPSLEEC QKAQIFTQMQ ALKYIGNKVR
60 70 80 90 100
RQRMWGGGPK KTKIEEAREL LASTILTHVP VKEFNFRAKC IYTAVMVRRV
110 120 130 140 150
ILAQGDNKVD DRDYYGNKRL ELAGQLLSLL FEDLFKKFNS EMKKIADQVI
160
PKQRAAQFDV VKHMRQDQI
Length:169
Mass (Da):19,479
Last modified:October 5, 2016 - v8
Checksum:i8ED5665471E199C1
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NW08RPC2_HUMAN
DNA-directed RNA polymerase III sub...
POLR3B
1,133Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei169Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009721 Genomic DNA No translation available.
AC078992 Genomic DNA No translation available.
AC080012 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000549569; ENSP00000448398; ENSG00000013503
UCSCiuc058sri.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009721 Genomic DNA No translation available.
AC078992 Genomic DNA No translation available.
AC080012 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF8VRU2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiF8VRU2
PRIDEiF8VRU2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000549569; ENSP00000448398; ENSG00000013503
UCSCiuc058sri.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000013503.9
HGNCiHGNC:30348 POLR3B
OpenTargetsiENSG00000013503
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0215 Eukaryota
COG0085 LUCA
GeneTreeiENSGT00920000149102

Miscellaneous databases

ChiTaRSiPOLR3B human

Gene expression databases

BgeeiENSG00000013503 Expressed in 189 organ(s), highest expression level in endometrium
ExpressionAtlasiF8VRU2 baseline and differential

Family and domain databases

Gene3Di3.90.1110.10, 1 hit
InterProiView protein in InterPro
IPR015712 DNA-dir_RNA_pol_su2
IPR007642 RNA_pol_Rpb2_2
IPR037034 RNA_pol_Rpb2_2_sf
PANTHERiPTHR20856 PTHR20856, 1 hit
PfamiView protein in Pfam
PF04561 RNA_pol_Rpb2_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8VRU2_HUMAN
AccessioniPrimary (citable) accession number: F8VRU2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 50 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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