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Protein

POU domain protein

Gene

Pou2f1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi394 – 453HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Pou2f1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:101898 Pou2f1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiF8VQL7
PeptideAtlasiF8VQL7
PRIDEiF8VQL7

Expressioni

Gene expression databases

BgeeiENSMUSG00000026565
ExpressionAtlasiF8VQL7 baseline and differential
GenevisibleiF8VQL7 MM

Structurei

3D structure databases

ProteinModelPortaliF8VQL7
SMRiF8VQL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini293 – 367POU-specificInterPro annotationAdd BLAST75
Domaini392 – 452HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802 Eukaryota
ENOG410XQ7X LUCA
GeneTreeiENSGT00760000118935

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
IPR013847 POU
IPR000327 POU_dom
IPR000972 TF_octamer
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF00157 Pou, 1 hit
PRINTSiPR00029 OCTAMER
PR00028 POUDOMAIN
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00352 POU, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS00035 POU_1, 1 hit
PS00465 POU_2, 1 hit
PS51179 POU_3, 1 hit

Sequencei

Sequence statusi: Complete.

F8VQL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDCSDCVLD SRMNNPSETN KSSMESEDAS TGTQTNGLDF QKQPVPVGGA
60 70 80 90 100
ISTAQAQAFL GHLHQVQLAG TSLQAAAQSL NVQSKSSEES GDSQQSSQPS
110 120 130 140 150
SQPPSVQSAI PQTQLMLAGG QITGLTLTPA QQQLLLQQAQ AQAQLLAAAV
160 170 180 190 200
QQHSASQQHS AAGATISASA ATPMTQIPLS QPIQIAQDLQ QLQQLQQQNL
210 220 230 240 250
NLQQFVLVHP TTNLQPAQFI ISQTPQGQQG LLQAQNLLTQ LPQQSQANLL
260 270 280 290 300
QPQPSITLTS QPTTPTRTIA AASVQTLPQS QSTPKRIDTP SLEEPSDLEE
310 320 330 340 350
LEQFAKTFKQ RRIKLGFTQG DVGLAMGKLY GNDFSQTTIS RFEALNLSFK
360 370 380 390 400
NMCKLKPLLE KWLNDAENLS SDSTASSPSA LNSPGLGAEG LNRRRKKRTS
410 420 430 440 450
IETNIRVALE KSFMENQKPT SEDITLIAEQ LNMEKEVIRV WFCNRRQKEK
460 470 480 490 500
RINPPSSGGT SSSPIKAIFP SPASLVATTP SLVTSSTATT LTVNPVLPLT
510 520 530 540 550
SAAVTNLSLT DQDLRRGCSW EVLRSLPDRV TTTAGTTDST SNNNTATVIS
560 570 580 590 600
TAPPASSAVT SPSLSPSPSA SASTSEASSA SETNTTQTTS TPLPSPLGAS
610 620 630 640 650
QVMVTTPGLQ TAAAALQGAA QLPANASLAA MAAAAGLSPG LMAPSQFAAG
660 670 680 690 700
GALLSLSPGT LGSALSPALM SNSTLATIQA LASSGSLPIT SLDATGNLVF
710 720 730 740 750
ANAGGAPNIV TAPLFLNPQN LSLLTSNPVS LVSAAAASTG NSAPTASLHA
760 770 780
SSTSTESIQS SLFTVASASG PASTTTAASK AQ
Length:782
Mass (Da):80,885
Last modified:September 21, 2011 - v1
Checksum:i006E1499AB276590
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093371 Genomic DNA No translation available.
RefSeqiNP_945152.2, NM_198934.3
UniGeneiMm.245261

Genome annotation databases

EnsembliENSMUST00000111427; ENSMUSP00000107056; ENSMUSG00000026565
GeneIDi18986
UCSCiuc007djw.2 mouse

Similar proteinsi

Entry informationi

Entry nameiF8VQL7_MOUSE
AccessioniPrimary (citable) accession number: F8VQL7
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: July 18, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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