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Protein
Submitted name:

Kinesin-like protein KIF13A

Gene

Kif13a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi102 – 109ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin-like protein KIF13AImported
Gene namesi
Name:Kif13aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:1098264 Kif13a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiF8VQ75
PeptideAtlasiF8VQ75
PRIDEiF8VQ75

Expressioni

Gene expression databases

BgeeiENSMUSG00000021375 Expressed in 260 organ(s), highest expression level in heart
ExpressionAtlasiF8VQ75 baseline and differential
GenevisibleiF8VQ75 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF8VQ75
SMRiF8VQ75
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 352Kinesin motorInterPro annotationAdd BLAST348

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili364 – 387Sequence analysisAdd BLAST24
Coiled coili389 – 409Sequence analysisAdd BLAST21
Coiled coili552 – 572Sequence analysisAdd BLAST21
Coiled coili607 – 634Sequence analysisAdd BLAST28
Coiled coili745 – 765Sequence analysisAdd BLAST21
Coiled coili1093 – 1120Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0245 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00930000150817
KOiK17914
OMAiPAGMETH
OrthoDBiEOG091G0091
TreeFamiTF105221

Family and domain databases

CDDicd00060 FHA, 1 hit
Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR000253 FHA_dom
IPR032923 KIF13A
IPR022164 Kinesin-like
IPR027640 Kinesin-like_fam
IPR022140 Kinesin-like_KIF1-typ
IPR032405 Kinesin_assoc
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR24115 PTHR24115, 1 hit
PTHR24115:SF458 PTHR24115:SF458, 1 hit
PfamiView protein in Pfam
PF12473 DUF3694, 1 hit
PF12423 KIF1B, 1 hit
PF00225 Kinesin, 1 hit
PF16183 Kinesin_assoc, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

F8VQ75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDTKVKVAV RVRPMNRREL ELNTKCVVEM EGNQTVLHPP PSNTKQGERK
60 70 80 90 100
PPKVFAFDYC FWSMDESNTT KYAGQEVVFK CLGEGILEKA FQGYNACIFA
110 120 130 140 150
YGQTGSGKSF SMMGHAEQLG LIPRLCCALF QRIALEQNES QTFKVEVSYM
160 170 180 190 200
EIYNEKVRDL LDPKGSRQSL KVREHKVLGP YVDGLSQLAV TSFEDIESLM
210 220 230 240 250
SEGNKSRTVA ATNMNEESSR SHAVFNIIIT QTLYDLQSGN SGEKVSKVSL
260 270 280 290 300
VDLAGSERVS KTGAAGERLK EGSNINKSLT TLGLVISSLA DQAAGKGKNK
310 320 330 340 350
FVPYRDSVLT WLLKDNLGGN SQTSMIATIS PAADNYEETL STLRYADRAK
360 370 380 390 400
RIVNHAVVNE DPNAKVIREL REEVEKLREQ LSQAEAMKAP ELKEKLEESE
410 420 430 440 450
KLIKELTVTW EEKLRKTEAI AQERQRQLES MGISLETSGI KVGDDKCYLV
460 470 480 490 500
NLNADPALNE LLVYYLKDHT RVGADTSQDI QLFGIGIQPE HCEIDIAADG
510 520 530 540 550
DITLTPKENA RSCVNGTLVC STTQLWHGDR ILWGNNHFFR INLPKRKRRD
560 570 580 590 600
WLKDFERETS SAEHDLDAAS EASSEPDYNY EFAQMEVIMK TLNSNDPVQN
610 620 630 640 650
VVQVLEKQYL EEKRTALEEQ RLMYERELEQ LRQQLSPERQ PPSSASDRLA
660 670 680 690 700
YSSQTAQQKV TQWAEERDEL FRQSLAKLRE QLVKANTLVR EANFLAEEMS
710 720 730 740 750
KLTDYQVTLQ IPAANLSANR KRGAIVSEPA IQARRKGKGT QVWTIEKLEN
760 770 780 790 800
KLIDMRDLYQ EWKENVPEAK RLYGKRGDPF YEAQENHNLI GVANVFLECL
810 820 830 840 850
FCDVKLQYAV PIISQQGEVA GRLHVEVTRI TGTIPERMAE DDSSENSSES
860 870 880 890 900
GSLEVVDSSG EVIHRVKKLT CRVIIKEATG LPISLSNFVF CQYTFWDQCE
910 920 930 940 950
STVAAPVVDP DVPSPQSKDA QYTVTFSHCK DYVVTVTEEF LEFISDGALA
960 970 980 990 1000
IEVWGHRCAG NGSPIWEVDS LHAKTRTLHD RWNEVTRRIE VWISILELNE
1010 1020 1030 1040 1050
LGDYAAVELH QAKDVNTGGV FQLRQGHSRR VQVTVKPVQH SGTLPLMVEA
1060 1070 1080 1090 1100
ILSVSIGCVT ARSTKLQRGL DSYQEEDLNC VRERWSDALI KRREYLDEQI
1110 1120 1130 1140 1150
KKVSNKKEKT EDDMEREARL VEQWVGLTEE RNAVLVPAPG SGIPGAPADW
1160 1170 1180 1190 1200
VPPPGMETHI PVLFLDLNAD DLSANEQLVG PHASGVNSIL PKEHGSQFFY
1210 1220 1230 1240 1250
LPIIKHSDDE VSATASWDSS VHDSLHLNRV TPQNERIYLI VKTTVQLSHP
1260 1270 1280 1290 1300
AAMELVLRKR IAANIYNKQS FTQSLKRRIS LINICYSCGV TYEIVSNIPK
1310 1320 1330 1340 1350
ATEEIEDRET LALLAARSEN EGTLDGETYI EKYTRGVLQV ENILSLERLR
1360 1370 1380 1390 1400
QAVTVKEALS TKARHIRRSL STPNVHNVSS SRPDLSGFDE DDKGWPENQL
1410 1420 1430 1440 1450
DVSDYSSSYQ DVACYGTLPR DSPRRSKEGC PSENPHALTV SPFKAFSPQP
1460 1470 1480 1490 1500
PKFFKPLMPV KEEHKKRLAL EARPLLSQED SEEEENELEA LSRKLMLTQP
1510 1520 1530 1540 1550
YVPVEFADFS VYNASLENRE WSSSKADLTD SRALEKAVSR SPTTSSLTSG
1560 1570 1580 1590 1600
YFSHSASNAT LSDMAVPSSD SSDQLAVSTK EVECAEPPGP SLAPDVRPAS
1610 1620 1630 1640 1650
NQELTEVGRG SGKDETIAVP LEENSALPKG TPSPQSIPEE SSRMPCRTAS
1660 1670 1680 1690 1700
CSELDVGPSK DGHQAREFCP GEVTIEHTTN ILEDHSFTEF MGVSDGKDFD
1710 1720 1730 1740
GLADCSVGEP SRRRALTNET DHKGIPERPP DADRLHPKIE NDQEATATR
Length:1,749
Mass (Da):195,701
Last modified:September 21, 2011 - v1
Checksum:i3C6AD300B6C59DFD
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9EQW7KI13A_MOUSE
Kinesin-like protein KIF13A
Kif13a
1,749Annotation score:
A0A286YDX6A0A286YDX6_MOUSE
Kinesin-like protein KIF13A
Kif13a
1,041Annotation score:
A0A286YEC5A0A286YEC5_MOUSE
Kinesin-like protein KIF13A
Kif13a
801Annotation score:
A0A286YDD6A0A286YDD6_MOUSE
Kinesin-like protein KIF13A
Kif13a
229Annotation score:
A0A286YCH2A0A286YCH2_MOUSE
Kinesin-like protein KIF13A
Kif13a
125Annotation score:
A0A286YDR8A0A286YDR8_MOUSE
Kinesin-like protein KIF13A
Kif13a
164Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124598 Genomic DNA No translation available.
AC134913 Genomic DNA No translation available.
RefSeqiNP_034747.2, NM_010617.2
UniGeneiMm.342703

Genome annotation databases

EnsembliENSMUST00000056978; ENSMUSP00000055304; ENSMUSG00000021375
GeneIDi16553
KEGGimmu:16553
UCSCiuc007qhn.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124598 Genomic DNA No translation available.
AC134913 Genomic DNA No translation available.
RefSeqiNP_034747.2, NM_010617.2
UniGeneiMm.342703

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5DJNX-ray2.82A/C355-445[»]
ProteinModelPortaliF8VQ75
SMRiF8VQ75
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF8VQ75
PeptideAtlasiF8VQ75
PRIDEiF8VQ75

Protocols and materials databases

DNASUi16553
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000056978; ENSMUSP00000055304; ENSMUSG00000021375
GeneIDi16553
KEGGimmu:16553
UCSCiuc007qhn.1 mouse

Organism-specific databases

CTDi63971
MGIiMGI:1098264 Kif13a

Phylogenomic databases

eggNOGiKOG0245 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00930000150817
KOiK17914
OMAiPAGMETH
OrthoDBiEOG091G0091
TreeFamiTF105221

Miscellaneous databases

ChiTaRSiKif13a mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021375 Expressed in 260 organ(s), highest expression level in heart
ExpressionAtlasiF8VQ75 baseline and differential
GenevisibleiF8VQ75 MM

Family and domain databases

CDDicd00060 FHA, 1 hit
Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR000253 FHA_dom
IPR032923 KIF13A
IPR022164 Kinesin-like
IPR027640 Kinesin-like_fam
IPR022140 Kinesin-like_KIF1-typ
IPR032405 Kinesin_assoc
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR24115 PTHR24115, 1 hit
PTHR24115:SF458 PTHR24115:SF458, 1 hit
PfamiView protein in Pfam
PF12473 DUF3694, 1 hit
PF12423 KIF1B, 1 hit
PF00225 Kinesin, 1 hit
PF16183 Kinesin_assoc, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8VQ75_MOUSE
AccessioniPrimary (citable) accession number: F8VQ75
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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