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Protein

FERM, ARHGEF and pleckstrin domain-containing protein 1

Gene

Farp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Guanine-nucleotide releasing factor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FERM, ARHGEF and pleckstrin domain-containing protein 1
Alternative name(s):
FERM, RhoGEF and pleckstrin domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Farp1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2446173 Farp1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse, Synaptosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004223361 – 1048FERM, ARHGEF and pleckstrin domain-containing protein 1Add BLAST1048

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei20PhosphoserineCombined sources1
Modified residuei23PhosphoserineCombined sources1
Modified residuei24PhosphothreonineCombined sources1
Modified residuei340PhosphoserineBy similarity1
Modified residuei373PhosphoserineCombined sources1
Modified residuei389PhosphoserineCombined sources1
Modified residuei403PhosphoserineCombined sources1
Modified residuei427PhosphoserineCombined sources1
Modified residuei433PhosphoserineCombined sources1
Modified residuei437PhosphoserineCombined sources1
Modified residuei512PhosphoserineCombined sources1
Modified residuei516PhosphoserineBy similarity1
Modified residuei836PhosphoserineBy similarity1
Modified residuei875PhosphoserineCombined sources1
Modified residuei881PhosphoserineCombined sources1
Modified residuei886PhosphothreonineBy similarity1
Modified residuei892PhosphoserineCombined sources1
Modified residuei899PhosphoserineCombined sources1
Modified residuei902PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F8VPU2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
F8VPU2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F8VPU2

PeptideAtlas

More...
PeptideAtlasi
F8VPU2

PRoteomics IDEntifications database

More...
PRIDEi
F8VPU2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F8VPU2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
F8VPU2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in brain cortex, hippocampus, striatum, olfactory bulb, cerebellum and hindbrain (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000025555 Expressed in 257 organ(s), highest expression level in dorsal pancreas

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F8VPU2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F8VPU2 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CADM1. Interacts with RAC1 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
230134, 3 interactors

Protein interaction database and analysis system

More...
IntActi
F8VPU2, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000026635

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
F8VPU2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F8VPU2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini40 – 320FERMPROSITE-ProRule annotationAdd BLAST281
Domaini542 – 733DHPROSITE-ProRule annotationAdd BLAST192
Domaini762 – 859PH 1PROSITE-ProRule annotationAdd BLAST98
Domaini935 – 1032PH 2PROSITE-ProRule annotationAdd BLAST98

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi449 – 455Poly-Glu7

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Intramolecular interaction between the DH domain and the PH domains can stabilize the protein in an autoinhibited conformation.By similarity

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3531 Eukaryota
ENOG410XP7Q LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155318

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007957

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F8VPU2

KEGG Orthology (KO)

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KOi
K17477

Identification of Orthologs from Complete Genome Data

More...
OMAi
MSIKIQM

Database of Orthologous Groups

More...
OrthoDBi
476668at2759

TreeFam database of animal gene trees

More...
TreeFami
TF351276

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14473 FERM_B-lobe, 1 hit
cd00160 RhoGEF, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.80.10, 1 hit
1.20.900.10, 1 hit
2.30.29.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019749 Band_41_domain
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR000798 Ez/rad/moesin-like
IPR014847 FERM-adjacent
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR029071 Ubiquitin-like_domsf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08736 FA, 1 hit
PF09380 FERM_C, 1 hit
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PF00169 PH, 2 hits
PF00621 RhoGEF, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00935 BAND41
PR00661 ERMFAMILY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00295 B41, 1 hit
SM01195 FA, 1 hit
SM01196 FERM_C, 1 hit
SM00233 PH, 2 hits
SM00325 RhoGEF, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47031 SSF47031, 1 hit
SSF48065 SSF48065, 1 hit
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50010 DH_2, 1 hit
PS00660 FERM_1, 1 hit
PS50057 FERM_3, 1 hit
PS50003 PH_DOMAIN, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F8VPU2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGEIEQKPTP ASRLGAPENS GISTLERGQK PPPTPSGKLM TVKIQMLDDT
60 70 80 90 100
QEAFEVPQRA PGKVLFDAVC NHLNLVEGDY FGLEFPDHRK IVVWLDLLKP
110 120 130 140 150
IVKQIRRPKH VVVKFVVKFF PPDHTQLQEE LTRYLFALQV KQDLAQGRLT
160 170 180 190 200
CNDTSAALLI SHIVQSEIGD FDEALDREHL AKNKYVPQQD ALEDRIMEFH
210 220 230 240 250
HSHVGQTPAE SDFQLLEVAR RLEMYGIRLH PAKDREGTKI NLAVANTGIL
260 270 280 290 300
VFQGFTKINA FNWAKVRKLS FKRKRFLIKL RPDVNSSYQD TLEFLMAGRD
310 320 330 340 350
FCKSFWKICV EHHAFFRLFE EPKPKPKPVL FSRGSSFRFS GRTQKQVLDY
360 370 380 390 400
VKEGGHKKVQ FERKHSKIHS TRSLVSQPTA PNSEVPKQSP QSASLTFGEG
410 420 430 440 450
TESPGGQSCQ QAKETKACTL ELGPHQSPAL PKSPPGSKAA DGTTVVPPEE
460 470 480 490 500
EEEEEGGKDG IRPSNPQPPQ PSTGSLTGSP HLSELSINSQ GGAAPANVTL
510 520 530 540 550
SPNLSPDNKQ ASPLISPLLN DQACPRTDDE EEGRRKRFPT DKAYYIAKEV
560 570 580 590 600
STTERTYLKD LEVIASWFQS TVSKEDSMPE ALKSLIFPNF EPLHKFHTNF
610 620 630 640 650
LKEIEQRLAL WEGRSNAHVR GDYQRIGDVM LKNIQGMKHL AAHLWKHSEA
660 670 680 690 700
LEALETSIKG SRRLEHFCRD FELQKVCYLP LNTFLLRPLH RLMHYKHVLE
710 720 730 740 750
RLCKHHPPNH ADFRDCRAAL AEITEMVAQL HGTMIKMENF QKLHELKKDL
760 770 780 790 800
IGIDNLVTPG REFIRLGSLS KLSGKGLQQR MFFLFNDVLL YTSRGLTASN
810 820 830 840 850
QFKVHGQLPL YGMTIEESEE EWGVPHCLTL RGQRQSIIVA ASSRSEMEKW
860 870 880 890 900
MEDIQMAIDL AEKSNGPTPE LLASSPPDNK SPDEATAADQ ESEDDLSASR
910 920 930 940 950
TSLERQAPHR GNTMVHVCWH RSTSVSMVDF SIAVENQLSG NLLRKFKNSN
960 970 980 990 1000
GWQKLWVVFT NFCLFFYKSH QDSHPLASLP LLGYSLTIPS ESENIHKDYV
1010 1020 1030 1040
FKLHFKSHVY YFRAESEYTF ERWMEVIRSA TSSASRAHIL SHKESHLY
Length:1,048
Mass (Da):118,875
Last modified:September 21, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6F626F96959B735A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q805E9Q805_MOUSE
FERM, ARHGEF and pleckstrin domain-...
Farp1
211Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti619V → I in AAI41230 (PubMed:15489334).Curated1
Sequence conflicti751I → V in AAI41230 (PubMed:15489334).Curated1
Sequence conflicti758T → I in AAI41230 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC154618 Genomic DNA No translation available.
AC165163 Genomic DNA No translation available.
AC167566 Genomic DNA No translation available.
BC141229 mRNA Translation: AAI41230.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37015.1

NCBI Reference Sequences

More...
RefSeqi
NP_598843.3, NM_134082.3
XP_006518977.1, XM_006518914.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.223980

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000026635; ENSMUSP00000026635; ENSMUSG00000025555

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
223254

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:223254

UCSC genome browser

More...
UCSCi
uc007vaa.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154618 Genomic DNA No translation available.
AC165163 Genomic DNA No translation available.
AC167566 Genomic DNA No translation available.
BC141229 mRNA Translation: AAI41230.1
CCDSiCCDS37015.1
RefSeqiNP_598843.3, NM_134082.3
XP_006518977.1, XM_006518914.3
UniGeneiMm.223980

3D structure databases

ProteinModelPortaliF8VPU2
SMRiF8VPU2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi230134, 3 interactors
IntActiF8VPU2, 2 interactors
STRINGi10090.ENSMUSP00000026635

PTM databases

iPTMnetiF8VPU2
PhosphoSitePlusiF8VPU2

Proteomic databases

jPOSTiF8VPU2
MaxQBiF8VPU2
PaxDbiF8VPU2
PeptideAtlasiF8VPU2
PRIDEiF8VPU2

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
223254
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000026635; ENSMUSP00000026635; ENSMUSG00000025555
GeneIDi223254
KEGGimmu:223254
UCSCiuc007vaa.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10160
MGIiMGI:2446173 Farp1

Phylogenomic databases

eggNOGiKOG3531 Eukaryota
ENOG410XP7Q LUCA
GeneTreeiENSGT00940000155318
HOGENOMiHOG000007957
InParanoidiF8VPU2
KOiK17477
OMAiMSIKIQM
OrthoDBi476668at2759
TreeFamiTF351276

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Farp1 mouse

Protein Ontology

More...
PROi
PR:F8VPU2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000025555 Expressed in 257 organ(s), highest expression level in dorsal pancreas
ExpressionAtlasiF8VPU2 baseline and differential
GenevisibleiF8VPU2 MM

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
cd00160 RhoGEF, 1 hit
Gene3Di1.20.80.10, 1 hit
1.20.900.10, 1 hit
2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR000798 Ez/rad/moesin-like
IPR014847 FERM-adjacent
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF08736 FA, 1 hit
PF09380 FERM_C, 1 hit
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PF00169 PH, 2 hits
PF00621 RhoGEF, 1 hit
PRINTSiPR00935 BAND41
PR00661 ERMFAMILY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SM01195 FA, 1 hit
SM01196 FERM_C, 1 hit
SM00233 PH, 2 hits
SM00325 RhoGEF, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF48065 SSF48065, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS00660 FERM_1, 1 hit
PS50057 FERM_3, 1 hit
PS50003 PH_DOMAIN, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFARP1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F8VPU2
Secondary accession number(s): C4IXU2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2013
Last sequence update: September 21, 2011
Last modified: January 16, 2019
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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